Experimental Hybridization in Leishmania: Tools for the Study of Genetic Exchange

por Ferreira, Tiago R., Sacks, David L.
Publicado 2022

A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes

por Huynh, Chau, Sacks, David L., Andrews, Norma W.
Publicado 2006

CRISPR/Cas9 Mutagenesis in Phlebotomus papatasi: the Immune Deficiency Pathway Impacts Vector Competence for Leishmania major

por Louradour, Isabelle, Ghosh, Kashinath, Inbar, Ehud, Sacks, David L.
Publicado 2019

Leishmania Sexual Reproductive Strategies as Resolved through Computational Methods Designed for Aneuploid Genomes

por Shaik, Jahangheer S., Dobson, Deborah E., Sacks, David L., Beverley, Stephen M.
Publicado 2021

Efficient Capture of Infected Neutrophils by Dendritic Cells in the Skin Inhibits the Early Anti-Leishmania Response

por Ribeiro-Gomes, Flavia L., Peters, Nathan C., Debrabant, Alain, Sacks, David L.
Publicado 2012

Uptake of Leishmania major Amastigotes Results in Activation and Interleukin 12 Release from Murine Skin–derived Dendritic Cells: Implications for the Initiation of Anti-Leishmania...

por von Stebut, Esther, Belkaid, Yasmine, Jakob, Thilo, Sacks, David L., Udey, Mark C.
Publicado 1998

Vector Transmission of Leishmania Abrogates Vaccine-Induced Protective Immunity

por Peters, Nathan C., Kimblin, Nicola, Secundino, Nagila, Kamhawi, Shaden, Lawyer, Phillip, Sacks, David L.
Publicado 2009

Leishmania major Survival in Selective Phlebotomus papatasi Sand Fly Vector Requires a Specific SCG-Encoded Lipophosphoglycan Galactosylation Pattern

por Dobson, Deborah E., Kamhawi, Shaden, Lawyer, Phillip, Turco, Salvatore J., Beverley, Stephen M., Sacks, David L.
Publicado 2010

The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti–IL-10 Receptor Antibody for Sterile Cure

por Belkaid, Yasmine, Hoffmann, Karl F., Mendez, Susana, Kamhawi, Shaden, Udey, Mark C., Wynn, Tom A., Sacks, David L.
Publicado 2001

Vaccination with DNA Encoding the Immunodominant LACK Parasite Antigen Confers Protective Immunity to Mice Infected with Leishmania major

por Gurunathan, Sanjay, Sacks, David L., Brown, Daniel R., Reiner, Steven L., Charest, Hughes, Glaichenhaus, Nicolas, Seder, Robert A.
Publicado 1997

Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of  Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the M...

por Belkaid, Yasmine, Kamhawi, Shaden, Modi, Govind, Valenzuela, Jesus, Noben-Trauth, Nancy, Rowton, Edgar, Ribeiro, José, Sacks, David L.
Publicado 1998

The Transcriptome of Leishmania major Developmental Stages in Their Natural Sand Fly Vector

por Inbar, Ehud, Hughitt, V. Keith, Dillon, Laura A. L., Ghosh, Kashinath, El-Sayed, Najib M., Sacks, David L.
Publicado 2017

Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment

por Lee, Sang Hun, Charmoy, Melanie, Romano, Audrey, Paun, Andrea, Chaves, Mariana M., Cope, Frederick O., Ralph, David A., Sacks, David L.
Publicado 2018

Dermis resident macrophages orchestrate localized ILC2-eosinophil circuitries to maintain their M2-like properties and promote non-healing cutaneous leishmaniasis

por Lee, Sang Hun, Kang, Byunghyun, Kamenyeva, Olena, Ferreira, Tiago Rodrigues, Cho, Kyoungin, Khillan, Jaspal S., Kabat, Juraj, Kelsall, Brian L., Sacks, David L.
Publicado 2023

Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis

por Lee, Sang Hun, Kang, Byunghyun, Kamenyeva, Olena, Ferreira, Tiago Rodrigues, Cho, Kyoungin, Khillan, Jaspal S., Kabat, Juraj, Kelsall, Brian L., Sacks, David L.
Publicado 2023

Toward a Defined Anti-Leishmania Vaccine Targeting Vector Antigens: Characterization of a Protective Salivary Protein

por Valenzuela, Jesus G., Belkaid, Yasmine, Garfield, Mark K., Mendez, Susana, Kamhawi, Shaden, Rowton, Edgar D., Sacks, David L., Ribeiro, José M.C.
Publicado 2001

Chronic Parasitic Infection Maintains High Frequencies of Short-Lived Ly6C(+)CD4(+) Effector T Cells That Are Required for Protection against Re-infection

por Peters, Nathan C., Pagán, Antonio J., Lawyer, Phillip G., Hand, Timothy W., Henrique Roma, Eric, Stamper, Lisa W., Romano, Audrey, Sacks, David L.
Publicado 2014

Infection Parameters in the Sand Fly Vector That Predict Transmission of Leishmania major

por Stamper, Lisa W., Patrick, Rachel L., Fay, Michael P., Lawyer, Phillip G., Elnaiem, Dia-Eldin A., Secundino, Nagila, Debrabant, Alain, Sacks, David L., Peters, Nathan C.
Publicado 2011

Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage

por Iantorno, Stefano A., Durrant, Caroline, Khan, Asis, Sanders, Mandy J., Beverley, Stephen M., Warren, Wesley C., Berriman, Matthew, Sacks, David L., Cotton, James A., Grigg, Michael E.
Publicado 2017

Fatal progression of experimental visceral leishmaniasis is associated with intestinal parasitism and secondary infection by commensal bacteria, and is delayed by antibiotic prophy...

por Lewis, Michael D., Paun, Andrea, Romano, Audrey, Langston, Harry, Langner, Charlotte A., Moore, Ian N., Bock, Kevin W., Francisco, Amanda Fortes, Brenchley, Jason M., Sacks, David L.
Publicado 2020