A Conserved Non-Canonical Docking Mechanism Regulates the Binding of Dual Specificity Phosphatases to Cell Integrity Mitogen-Activated Protein Kinases (MAPKs) in Budding and Fissio...

por Sacristán-Reviriego, Almudena, Madrid, Marisa, Cansado, José, Martín, Humberto, Molina, María
Publicado 2014

Retinal Organoids from an AIPL1 CRISPR/Cas9 Knockout Cell Line Successfully Recapitulate the Molecular Features of LCA4 Disease

por Perdigão, Pedro R. L., Ollington, Bethany, Sai, Hali, Leung, Amy, Sacristan-Reviriego, Almudena, van der Spuy, Jacqueline
Publicado 2023

Distinct Docking Mechanisms Mediate Interactions between the Msg5 Phosphatase and Mating or Cell Integrity Mitogen-activated Protein Kinases (MAPKs) in Saccharomyces cerevisiae

por Palacios, Lorena, Dickinson, Robin J., Sacristán-Reviriego, Almudena, Didmon, Mark P., Marín, María José, Martín, Humberto, Keyse, Stephen M., Molina, María
Publicado 2011

The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6

por Sacristan-Reviriego, Almudena, Bellingham, James, Prodromou, Chrisostomos, Boehm, Annika N, Aichem, Annette, Kumaran, Neruban, Bainbridge, James, Michaelides, Michel, van der Spuy, Jacqueline
Publicado 2017

The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6

por Sacristan-Reviriego, Almudena, Bellingham, James, Prodromou, Chrisostomos, Boehm, Annika N, Aichem, Annette, Kumaran, Neruban, Bainbridge, James, Michaelides, Michel, van der Spuy, Jacqueline
Publicado 2018

Clinical and functional analyses of AIPL1 variants reveal mechanisms of pathogenicity linked to different forms of retinal degeneration

por Sacristan-Reviriego, Almudena, Le, Hoang Mai, Georgiou, Michalis, Meunier, Isabelle, Bocquet, Beatrice, Roux, Anne-Françoise, Prodromou, Chrisostomos, Bainbridge, James, Michaelides, Michel, van der Spuy, Jacqueline
Publicado 2020

Investigation of PTC124-mediated translational readthrough in a retinal organoid model of AIPL1-associated Leber congenital amaurosis

por Leung, Amy, Sacristan-Reviriego, Almudena, Perdigão, Pedro R.L., Sai, Hali, Georgiou, Michalis, Kalitzeos, Angelos, Carr, Amanda-Jayne F., Coffey, Peter J., Michaelides, Michel, Bainbridge, James, Cheetham, Michael E., van der Spuy, Jacqueline
Publicado 2022