Activation of GPR40 attenuates chronic inflammation induced impact on pancreatic β-cells health and function

por Verma, Mahesh Kumar, Sadasivuni, Manoj Kumar, Yateesh, Aggunda N, Neelima, Korrapati, Mrudula, Srikanth, Reddy, Madhusudhan, Smitha, Rachapalli, Biswas, Sanghamitra, Chandravanshi, Bhawna, Pallavi, Puttrevana M, Oommen, Anup M, Jagannath, Madanahalli R, Somesh, Baggavalli B
Publicado 2014

Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity

por Somesh, Baggavalli P, Verma, Mahesh Kumar, Sadasivuni, Manoj Kumar, Mammen-Oommen, Anup, Biswas, Sanghamitra, Shilpa, Pavagada C, Reddy, Ashok Kumar, Yateesh, Aggunda N, Pallavi, Puttrevana M, Nethra, Siddaraju, Smitha, Rachapalli, Neelima, Korrapati, Narayanan, Usha, Jagannath, Madanahalli R
Publicado 2013

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potentia...

por Anil, Tharappel M, Dandu, Anilkumar, Harsha, KrishnaReddy, Singh, Jaideep, Shree, Nitya, Kumar, Venkatesh Satish, Lakshmi, Mudigere N, Sunil, Venkategowda, Harish, Chandrashekaran, Balamurali, Gundalmandikal V, Naveen Kumar, Baisani S, Gopala, Aralakuppe S, Pratibha, Shivakumar, Sadasivuni, ManojKumar, Anup, Mammen O, Moolemath, Yoganand, Venkataranganna, Marikunte V, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado 2014

CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridem...

por Sadasivuni, Manoj Kumar, Reddy, Bobbili Madhusudhan, Singh, Jaideep, Anup, Mammen O, Sunil, Venkategowda, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Chacko, Suni K, Pooja, Talanki Lokesh, Dandu, Anilkumar, Harish, Chandrashekaran, Gopala, Aralakuppe S, Pratibha, Shivakumar, Naveenkumar, Baisani S, Pallavi, Puttrevana M, Verma, Mahesh Kumar, Moolemath, Yoganand, Somesh, Baggavalli P, Venkataranganna, Marikunte V, Jagannath, Madanahalli R
Publicado 2014