Genetic association studies using disease liabilities from deep neural networks

por Yang, Lu, Sadler, Marie C., Altman, Russ B.
Publicado 2023

Multi-layered genetic approaches to identify approved drug targets

por Sadler, Marie C., Auwerx, Chiara, Deelen, Patrick, Kutalik, Zoltán
Publicado 2023

Promises and challenges in pharmacoepigenetics

por Smith, Delaney A., Sadler, Marie C., Altman, Russ B.
Publicado 2023

From pharmacogenetics to pharmaco-omics: Milestones and future directions

por Auwerx, Chiara, Sadler, Marie C., Reymond, Alexandre, Kutalik, Zoltán
Publicado 2022

Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases

por Sadler, Marie C., Auwerx, Chiara, Lepik, Kaido, Porcu, Eleonora, Kutalik, Zoltán
Publicado 2022

Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations

por Auwerx, Chiara, Sadler, Marie C, Woh, Tristan, Reymond, Alexandre, Kutalik, Zoltán, Porcu, Eleonora
Publicado 2023

The individual and global impact of copy-number variants on complex human traits

por Auwerx, Chiara, Lepamets, Maarja, Sadler, Marie C., Patxot, Marion, Stojanov, Miloš, Baud, David, Mägi, Reedik, Porcu, Eleonora, Reymond, Alexandre, Kutalik, Zoltán
Publicado 2022

The impact of 22q11.2 copy-number variants on human traits in the general population

por Zamariolli, Malú, Auwerx, Chiara, Sadler, Marie C., van der Graaf, Adriaan, Lepik, Kaido, Schoeler, Tabea, Moysés-Oliveira, Mariana, Dantas, Anelisa G., Melaragno, Maria Isabel, Kutalik, Zoltán
Publicado 2023

Chromosomal deletions on 16p11.2 encompassing SH2B1 are associated with accelerated metabolic disease

por Hanssen, Ruth, Auwerx, Chiara, Jõeloo, Maarja, Sadler, Marie C., Henning, Elana, Keogh, Julia, Bounds, Rebecca, Smith, Miriam, Firth, Helen V., Kutalik, Zoltán, Farooqi, I. Sadaf, Reymond, Alexandre, Lawler, Katherine
Publicado 2023

Author Correction: Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts

por Giannuzzi, Giuliana, Chatron, Nicolas, Mannik, Katrin, Auwerx, Chiara, Pradervand, Sylvain, Willemin, Gilles, Hoekzema, Kendra, Nuttle, Xander, Chrast, Jacqueline, Sadler, Marie C., Porcu, Eleonora, Herault, Yann, Isidor, Bertrand, Gilbert-Dussardier, Brigitte, Eichler, Evan E., Kutalik, Zoltan, Reymond, Alexandre
Publicado 2023

Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts

por Giannuzzi, Giuliana, Chatron, Nicolas, Mannik, Katrin, Auwerx, Chiara, Pradervand, Sylvain, Willemin, Gilles, Hoekzema, Kendra, Nuttle, Xander, Chrast, Jacqueline, Sadler, Marie C., Porcu, Eleonora, Herault, Yann, Isidor, Bertrand, Gilbert-Dussardier, Brigitte, Eichler, Evan E., Kutalik, Zoltan, Reymond, Alexandre
Publicado 2022

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

por Porcu, Eleonora, Sadler, Marie C., Lepik, Kaido, Auwerx, Chiara, Wood, Andrew R., Weihs, Antoine, Sleiman, Maroun S. Bou, Ribeiro, Diogo M., Bandinelli, Stefania, Tanaka, Toshiko, Nauck, Matthias, Völker, Uwe, Delaneau, Olivier, Metspalu, Andres, Teumer, Alexander, Frayling, Timothy, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán
Publicado 2021