Surgical Strikes on Host Defenses: Role of the Viral Protease Activity in Innate Immune Antagonism

por Chin, Chue Vin, Saeed, Mohsan
Publicado 2022

SARS-CoV-2 nonstructural protein 6 from Alpha to Omicron: evolution of a transmembrane protein

por Feng, Shuchen, O'Brien, Amornrat, Chen, Da-Yuan, Saeed, Mohsan, Baker, Susan C.
Publicado 2023

Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication

por Rusanov, Timur, Kent, Tatiana, Saeed, Mohsan, Hoang, Trung M., Thomas, Crystal, Rice, Charles M., Pomerantz, Richard T.
Publicado 2018

Epidemiology and clinical findings associated with enteroviral acute flaccid paralysis in Pakistan

por Saeed, Mohsan, Zaidi, Sohail Z, Naeem, Asif, Masroor, Muhammad, Sharif, Salmaan, Shaukat, Shahzad, Angez, Mehar, Khan, Anis
Publicado 2007

SEC14L2 enables pan-genotype HCV replication in cell culture

por Saeed, Mohsan, Andreo, Ursula, Chung, Hyo-Young, Espiritu, Christine, Branch, Andrea D., Silva, Jose M., Rice, Charles M.
Publicado 2015

Inhibition of Sars-Cov-2 Viral Replication and In Vivo Thrombus Formation By a Novel Plant Flavonoid

por Yang, Moua, Lin, Lin, Scartelli, Christina, Chen, Da-Yuan, Patel, Anika, Bekendam, Roelof, Sun, Lijun, Saeed, Mohsan, Flaumenhaft, Robert
Publicado 2021

Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication

por Lin, Lin, Chen, Da-Yuan, Scartelli, Christina, Xie, Huanzhang, Merrill-Skoloff, Glenn, Yang, Moua, Sun, Lijun, Saeed, Mohsan, Flaumenhaft, Robert
Publicado 2023

Detecting SARS-CoV-2 3CLpro expression and activity using a polyclonal antiserum and a luciferase-based biosensor

por O'Brien, Amornrat, Chen, Da-Yuan, Hackbart, Matthew, Close, Brianna J., O'Brien, Timothy E., Saeed, Mohsan, Baker, Susan C.
Publicado 2021

Drug repositioning candidates identified using in-silico quasi-quantum molecular simulation demonstrate reduced COVID-19 mortality in 1.5M patient records

por Alamgir, Joy, Yajima, Masanao, Ergas, Rosa, Chen, Xinci, Hill, Nicholas, Munir, Naved, Saeed, Mohsan, Gersing, Ken, Haendel, Melissa, Chute, Christopher G, Abid, M. Ruhul
Publicado 2021

Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease

por Serganov, Artem A., Udi, Yael, Stein, Milana E., Patel, Valay, Fridy, Peter C., Rice, Charles M., Saeed, Mohsan, Jacobs, Erica Y., Chait, Brian T., Rout, Michael P.
Publicado 2022

DNA templates with blocked long 3ʹ end single-stranded overhangs (BL3SSO) promote bona fide Cas9-stimulated homology-directed repair of long transgenes into endogenous gene loci

por Bandyopadhyay, Saptaparni, Douglass, Joseph, Kapell, Sebastian, Khan, Nazimuddin, Feitosa-Suntheimer, Fabiana, Klein, Jenny A, Temple, Jasmine, Brown-Culbertson, Jayce, Tavares, Alexander H, Saeed, Mohsan, Lau, Nelson C
Publicado 2021

The in-vitro effect of famotidine on sars-cov-2 proteases and virus replication

por Loffredo, Madeline, Lucero, Hector, Chen, Da-Yuan, O’Connell, Aoife, Bergqvist, Simon, Munawar, Ahmad, Bandara, Asanga, De Graef, Steff, Weeks, Stephen D., Douam, Florian, Saeed, Mohsan, Munawar, Ali H.
Publicado 2021

HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses

por Weingarten-Gabbay, Shira, Pearlman, Leah R., Chen, Da-Yuan, Klaeger, Susan, Taylor, Hannah B., Welch, Nicole L., Keskin, Derin B., Carr, Steven A., Abelin, Jennifer G., Saeed, Mohsan, Sabeti, Pardis C.
Publicado 2022

Developing a SARS-CoV-2 antigen test using engineered affinity proteins

por Kim, Seunghyeon, Yee, Emma, Miller, Eric A., Hao, Yining, Tay, Dousabel M. Y., Sung, Ki-Joo, Jia, Huan, Johnson, Joseph M., Saeed, Mohsan, Mace, Charles R., Yurt, Deniz Yüksel, Sikes, Hadley D.
Publicado 2021

Identification, Molecular Cloning, and Analysis of Full-Length Hepatitis C Virus Transmitted/Founder Genotypes 1, 3, and 4

por Stoddard, Mark B., Li, Hui, Wang, Shuyi, Saeed, Mohsan, Andrus, Linda, Ding, Wenge, Jiang, Xinpei, Learn, Gerald H., von Schaewen, Markus, Wen, Jessica, Goepfert, Paul A., Hahn, Beatrice H., Ploss, Alexander, Rice, Charles M., Shaw, George M.
Publicado 2015

Visualization of Positive and Negative Sense Viral RNA for Probing the Mechanism of Direct-Acting Antivirals against Hepatitis C Virus

por Liu, Dandan, Tedbury, Philip R., Lan, Shuiyun, Huber, Andrew D., Puray-Chavez, Maritza N., Ji, Juan, Michailidis, Eleftherios, Saeed, Mohsan, Ndongwe, Tanyaradzwa P., Bassit, Leda C., Schinazi, Raymond F., Ralston, Robert, Rice, Charles M., Sarafianos, Stefan G.
Publicado 2019

Defining the proteolytic landscape during enterovirus infection

por Saeed, Mohsan, Kapell, Sebastian, Hertz, Nicholas T., Wu, Xianfang, Bell, Kierstin, Ashbrook, Alison W., Mark, Milica Tesic, Zebroski, Henry A., Neal, Maxwell L., Flodström-Tullberg, Malin, MacDonald, Margaret R., Aitchison, John D., Molina, Henrik, Rice, Charles M.
Publicado 2020

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection

por Ren, Wenlin, Zhu, Yunkai, Lan, Jun, Chen, Hedi, Wang, Yuyan, Shi, Hongyang, Feng, Fei, Chen, Da-Yuan, Close, Brianna, Zhao, Xiaomin, Wu, Jianping, Tian, Boxue, Yuan, Zhenghong, Zhou, Dongming, Saeed, Mohsan, Wang, Xinquan, Zhang, Rong, Ding, Qiang
Publicado 2022

Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo

por Torchia, James A., Tavares, Alexander H., Carstensen, Laura S., Chen, Da-Yuan, Huang, Jessie, Xiao, Tianshu, Mukherjee, Sonia, Reeves, Patrick M., Tu, Hua, Sluder, Ann E., Chen, Bing, Kotton, Darrell N., Bowen, Richard A., Saeed, Mohsan, Poznansky, Mark C., Freeman, Gordon J.
Publicado 2022

SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

por Sanders, David W, Jumper, Chanelle C, Ackerman, Paul J, Bracha, Dan, Donlic, Anita, Kim, Hahn, Kenney, Devin, Castello-Serrano, Ivan, Suzuki, Saori, Tamura, Tomokazu, Tavares, Alexander H, Saeed, Mohsan, Holehouse, Alex S, Ploss, Alexander, Levental, Ilya, Douam, Florian, Padera, Robert F, Levy, Bruce D, Brangwynne, Clifford P
Publicado 2021