Therapeutic options for treatment of human papillomavirus-associated cancers - novel immunologic vaccines: ADXS11–001

por Miles, Brett, Safran, Howard P., Monk, Bradley J.
Publicado 2017

Mechanistic insights into ADXS11-001 human papillomavirus-associated cancer immunotherapy

por Miles, Brett A., Monk, Bradley J., Safran, Howard P.
Publicado 2017

AMG-232 sensitizes high MDM2-expressing tumor cells to T-cell-mediated killing

por Sahin, Ilyas, Zhang, Shengliang, Navaraj, Arunasalam, Zhou, Lanlan, Dizon, Don, Safran, Howard, El-Deiry, Wafik S.
Publicado 2020

Correction: AMG-232 sensitizes high MDM2-expressing tumor cells to T-cell-mediated killing

por Sahin, Ilyas, Zhang, Shengliang, Navaraj, Arunasalam, Zhou, Lanlan, Dizon, Don, Safran, Howard, El-Deiry, Wafik S.
Publicado 2020

Strategies to sensitize cancer cells to immunotherapy

por George, Andrew, Sahin, Ilyas, Carneiro, Benedito A., Dizon, Don S., Safran, Howard P., El-Deiry, Wafik S.
Publicado 2021

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma

por Marks, Eric I., Pamarthy, Sahithi, Dizon, Don, Birnbaum, Ari, Yakirevich, Evgeny, Safran, Howard, Carneiro, Benedito A.
Publicado 2023

Nonengraftment Haploidentical Cellular Therapy for Hematologic Malignancies

por Reagan, John L., Fast, Loren D., Winer, Eric S., Safran, Howard, Butera, James N., Quesenberry, Peter J.
Publicado 2012

ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma

por Marks, Eric I., Pamarthy, Sahithi, Dizon, Don, Birnbaum, Ari, Yakirevich, Evgeny, Safran, Howard, Carneiro, Benedito A.
Publicado 2019

Dosimetric Feasibility of Dose Escalation Using SBRT Boost for Stage III Non-Small Cell Lung Cancer

por Hepel, Jaroslaw T., Peter, Justin, Hiatt, Jessica R., Patel, Salil, Osibanjo, Oluwademilade, Safran, Howard, Curran, Bruce, DiPetrillo, Thomas
Publicado 2012

Informed consent in oncology clinical trials: A Brown University Oncology Research Group prospective cross-sectional pilot study

por Schumacher, Andrew, Sikov, William M., Quesenberry, Matthew I., Safran, Howard, Khurshid, Humera, Mitchell, Kristen M., Olszewski, Adam J.
Publicado 2017

EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor...

por Zhang, Yiqun, Zhou, Lanlan, Safran, Howard, Borsuk, Robyn, Lulla, Rishi, Tapinos, Nikos, Seyhan, Attila A., El-Deiry, Wafik S.
Publicado 2021

Commentary: GSK-3 Inhibition as a Therapeutic Approach Against SARs CoV2: Dual Benefit of Inhibiting Viral Replication While Potentiating the Immune Response

por De Souza, Andre, Tavora, Fabio A., Mahalingam, Devalingam, Munster, Pamela N., Safran, Howard P., El-Deiry, Wafik S., Carneiro, Benedito A.
Publicado 2020

Weekly paclitaxel, gemcitabine, and external irradiation followed by randomized farnesyl transferase inhibitor R115777 for locally advanced pancreatic cancer

por Rich, Tyvin A, Winter, Kathryn, Safran, Howard, Hoffman, John P, Erickson, Beth, Anne, Pramila R, Myerson, Robert J, Cline-Burkhardt, Vivian JM, Perez, Kimberly, Willett, Christopher
Publicado 2012

Cellular immunotherapy for refractory hematological malignancies

por Reagan, John L, Fast, Loren D, Safran, Howard, Nevola, Martha, Winer, Eric S, Castillo, Jorge J, Butera, James N, Quesenberry, Matthew I, Young, Carolyn T, Quesenberry, Peter J
Publicado 2013

Electrocardiographic Characterization of Ramucirumab on the Corrected QT Interval in a Phase II Study of Patients With Advanced Solid Tumors

por Olszanski, Anthony J., Smith, David C., Camacho, Luis H., Thompson, John, Ramalingam, Suresh S., Harvey, R. Donald, Campos, Luis, Ferry, David, Tang, Shande, Gao, Ling, Safran, Howard
Publicado 2016

A Phase I Study of Dasatinib with Concurrent Chemoradiation for Stage III Non-Small Cell Lung Cancer

por Khurshid, Humera, Dipetrillo, Thomas, Ng, Thomas, Mantripragada, Kalyan, Birnbaum, Ariel, Berz, David, Radie-Keane, Kathy, Perez, Kimberly, Constantinou, Maria, Luppe, Denise, Schumacher, Andrew, Leonard, Kara, Safran, Howard
Publicado 2012

Eltrombopag with gemcitabine-based chemotherapy in patients with advanced solid tumors: a randomized phase I study

por Winer, Eric S, Safran, Howard, Karaszewska, Boguslawa, Richards, Donald A, Hartner, Lee, Forget, Frederic, Ramlau, Rodryg, Kumar, Kirushna, Mayer, Bhabita, Johnson, Brendan M, Messam, Conrad A, Mostafa Kamel, Yasser
Publicado 2015

Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo

por Jhaveri, Aakash V., Zhou, Lanlan, Ralff, Marie D., Lee, Young S., Navaraj, Arunasalam, Carneiro, Benedito A., Safran, Howard, Prabhu, Varun V., Ross, Eric A., Lee, Seulki, El-Deiry, Wafik S.
Publicado 2021

The Brown University Oncology Group Experience With FOLFOX + Nab-paclitaxel [FOLFOX-A] for Metastatic and Locally Advanced Pancreatic, BrUOG-292 and BrUOG-318

por Breakstone, Rimini, Almhanna, Khaldoun, Raufi, Alexander, Beard, Rachel E., Leonard, Kara-Lynne, Renaud, Jennifer, Kastura, Michaela, Dionson, Sopha, Wood, Roxanne, Sturtevant, Ashlee, Dipetrillo, Thomas, Olszewski, Adam, Safran, Howard
Publicado 2022

Phase I study to assess the effect of adavosertib (AZD1775) on the pharmacokinetics of substrates of CYP1A2, CYP2C19, and CYP3A in patients with advanced solid tumors

por Någård, Mats, Ah-See, Mei-Lin, Strauss, James, Wise-Draper, Trisha, Safran, Howard P., Nadeau, Laura, Edenfield, William J., Lewis, Lionel D., Ottesen, Lone H., Li, Yan, Mugundu, Ganesh M.
Publicado 2023