Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease

por Sweeney, Melanie D, Sagare, Abhay P, Zlokovic, Berislav V
Publicado 2015

Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: the role, regulation and restoration of LRP1

por Ramanathan, Anita, Nelson, Amy R., Sagare, Abhay P., Zlokovic, Berislav V.
Publicado 2015

3K3A-activated protein C blocks amyloidogenic BACE1 pathway and improves functional outcome in mice

por Lazic, Divna, Sagare, Abhay P., Nikolakopoulou, Angeliki M., Griffin, John H., Vassar, Robert, Zlokovic, Berislav V.
Publicado 2019

Author Correction: Pericyte loss influences Alzheimer-like neurodegeneration in mice

por Sagare, Abhay P., Bell, Robert D., Zhao, Zhen, Ma, Qingyi, Winkler, Ethan A., Ramanathan, Anita, Zlokovic, Berislav V.
Publicado 2023

Pericyte loss influences Alzheimer-like neurodegeneration in mice

por Sagare, Abhay P., Bell, Robert D., Zhao, Zhen, Ma, Qingyi, Winkler, Ethan A., Ramanathan, Anita, Zlokovic, Berislav V.
Publicado 2013

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

por Ma, Qingyi, Zhao, Zhen, Sagare, Abhay P, Wu, Yingxi, Wang, Min, Owens, Nelly Chuqui, Verghese, Philip B, Herz, Joachim, Holtzman, David M, Zlokovic, Berislav V
Publicado 2018

Correction: Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

por Ma, Qingyi, Zhao, Zhen, Sagare, Abhay P., Wu, Yingxi, Wang, Min, Owens, Nelly Chuqui, Verghese, Philip B., Herz, Joachim, Holtzman, David M., Zlokovic, Berislav V.
Publicado 2022

Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier

por Kisler, Kassandra, Sagare, Abhay P., Lazic, Divna, Bazzi, Sam, Lawson, Erica, Hsu, Ching-Ju, Wang, Yaoming, Ramanathan, Anita, Nelson, Amy R., Zhao, Zhen, Zlokovic, Berislav V.
Publicado 2023

Correction: Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier

por Kisler, Kassandra, Sagare, Abhay P., Lazic, Divna, Bazzi, Sam, Lawson, Erica, Hsu, Ching-Ju, Wang, Yaoming, Ramanathan, Anita, Nelson, Amy R., Zhao, Zhen, Zlokovic, Berislav V.
Publicado 2023

Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C

por Huuskonen, Mikko T., Wang, Yaoming, Nikolakopoulou, Angeliki Maria, Montagne, Axel, Dai, Zhonghua, Lazic, Divna, Sagare, Abhay P., Zhao, Zhen, Fernandez, Jose A., Griffin, John H., Zlokovic, Berislav V.
Publicado 2021

Evidence that blood–CSF barrier transport, but not inflammatory biomarkers, change in migraine, while CSF sVCAM1 associates with migraine frequency and CSF fibrinogen

por Cowan, Robert P., Gross, Noah B., Sweeney, Melanie D., Sagare, Abhay P., Montagne, Axel, Arakaki, Xianghong, Fonteh, Alfred N., Zlokovic, Berislav V., Pogoda, Janice M., Harrington, Michael G.
Publicado 2021

Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A

por Nikolakopoulou, Angeliki Maria, Wang, Yaoming, Ma, Qingyi, Sagare, Abhay P., Montagne, Axel, Huuskonen, Mikko T., Rege, Sanket V., Kisler, Kassandra, Dai, Zhonghua, Körbelin, Jakob, Herz, Joachim, Zhao, Zhen, Zlokovic, Berislav V.
Publicado 2021

A “multi-omics” analysis of blood–brain barrier and synaptic dysfunction in APOE4 mice

por Barisano, Giuseppe, Kisler, Kassandra, Wilkinson, Brent, Nikolakopoulou, Angeliki Maria, Sagare, Abhay P., Wang, Yaoming, Gilliam, William, Huuskonen, Mikko T., Hung, Shu-Ting, Ichida, Justin K., Gao, Fan, Coba, Marcelo P., Zlokovic, Berislav V.
Publicado 2022

Functional connectivity among brain regions affected in Alzheimer’s disease is associated with CSF TNF-α in APOE4 carriers

por Contreras, Joey Annette, Aslanyan, Vahan, Sweeney, Melanie D., Sanders, Lianne M.J., Sagare, Abhay P., Zlokovic, Berislav V., Toga, Arthur W., Han, S. Duke, Morris, John C., Fagan, Anne, Massoumzadeh, Parinaz, Benzinger, Tammie L., Pa, Judy
Publicado 2019

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

por Nikolakopoulou, Angeliki M., Montagne, Axel, Kisler, Kassandra, Dai, Zhonghua, Wang, Yaoming, Huuskonen, Mikko T., Sagare, Abhay P., Lazic, Divna, Sweeney, Melanie D., Kong, Pan, Wang, Min, Owens, Nelly Chuqui, Lawson, Erica J., Xie, Xiaochun, Zhao, Zhen, Zlokovic, Berislav V.
Publicado 2019

Correction: Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline

por Asanad, Samuel, Fantini, Michele, Sultan, William, Nassisi, Marco, Felix, Christian M., Wu, Jessica, Karanjia, Rustum, Ross-Cisneros, Fred N., Sagare, Abhay P., Zlokovic, Berislav V., Chui, Helena C., Pogoda, Janice M., Arakaki, Xianghong, Fonteh, Alfred N., Sadun, Alfredo A., Harrington, Michael G.
Publicado 2020

Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline

por Asanad, Samuel, Fantini, Michele, Sultan, William, Nassisi, Marco, Felix, Christian M., Wu, Jessica, Karanjia, Rustum, Ross-Cisneros, Fred N., Sagare, Abhay P., Zlokovic, Berislav V., Chui, Helena C., Pogoda, Janice M., Arakaki, Xianghong, Fonteh, Alfred N., Sadun A. A., Alfredo A., Harrington, Michael G.
Publicado 2020

Central role for PICALM in amyloid–β blood–brain barrier transcytosis and clearance

por Zhao, Zhen, Sagare, Abhay P., Ma, Qingyi, Halliday, Matthew R., Kong, Pan, Kisler, Kassandra, Winkler, Ethan A., Ramanathan, Anita, Kanekiyo, Takahisa, Bu, Guojun, Owens, Nelly Chuqui, Rege, Sanket V., Si, Gabriel, Ahuja, Ashim, Zhu, Donghui, Miller, Carol A., Schneider, Julie A., Maeda, Manami, Maeda, Takahiro, Sugawara, Tohru, Ichida, Justin K., Zlokovic, Berislav V.
Publicado 2015

Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction

por Nation, Daniel A., Sweeney, Melanie D., Montagne, Axel, Sagare, Abhay P., D’Orazio, Lina M., Pachicano, Maricarmen, Sepehrband, Farshid, Nelson, Amy R., Buennagel, David P., Harrington, Michael G., Benzinger, Tammie L.S., Fagan, Anne M., Ringman, John M., Schneider, Lon S., Morris, John C., Chui, Helena C., Law, Meng, Toga, Arthur W., Zlokovic, Berislav V.
Publicado 2019

APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline

por Montagne, Axel, Nation, Daniel A., Sagare, Abhay P., Barisano, Giuseppe, Sweeney, Melanie D., Chakhoyan, Ararat, Pachicano, Maricarmen, Joe, Elizabeth, Nelson, Amy R., D’Orazio, Lina M., Buennagel, David P., Harrington, Michael G., Benzinger, Tammie L. S., Fagan, Anne M., Ringman, John M., Schneider, Lon S., Morris, John C., Reiman, Eric M., Caselli, Richard J., Chui, Helena C., TCW, Julia, Chen, Yining, Pa, Judy, Conti, Peter S., Law, Meng, Toga, Arthur W., Zlokovic, Berislav V.
Publicado 2020