Sporadic renal angiomyolipoma in a patient with Birt-Hogg-Dubé: chaperones in pathogenesis

por Sager, Rebecca A., Woodford, Mark R., Shapiro, Oleg, Mollapour, Mehdi, Bratslavsky, Gennady
Publicado 2018

Emerging Link between Tsc1 and FNIP Co-Chaperones of Hsp90 and Cancer

por Backe, Sarah J., Sager, Rebecca A., Meluni, Katherine A., Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi
Publicado 2022

Targeting extracellular Hsp90: A unique frontier against cancer

por Sager, Rebecca A., Khan, Farzana, Toneatto, Lorenzo, Votra, SarahBeth D., Backe, Sarah J., Woodford, Mark R., Mollapour, Mehdi, Bourboulia, Dimitra
Publicado 2022

A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand

por Backe, Sarah J., Sager, Rebecca A., Regan, Bethany R., Sit, Julian, Major, Lauren A., Bratslavsky, Gennady, Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi
Publicado 2022

Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery

por Backe, Sarah J., Sager, Rebecca A., Heritz, Jennifer A., Wengert, Laura A., Meluni, Katherine A., Aran-Guiu, Xavier, Panaretou, Barry, Woodford, Mark R., Prodromou, Chrisostomos, Bourboulia, Dimitra, Mollapour, Mehdi
Publicado 2023

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity

por Woodford, Mark R., Hughes, Michael, Sager, Rebecca A., Backe, Sarah J., Baker-Williams, Alexander J., Bratslavsky, Michael S., Jacob, Joseph M., Shapiro, Oleg, Wong, Michael, Bratslavsky, Gennady, Bourboulia, Dimitra, Mollapour, Mehdi
Publicado 2019

Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients

por Woodford, Mark R, Sager, Rebecca A, Marris, Elijah, Dunn, Diana M, Blanden, Adam R, Murphy, Ryan L, Rensing, Nicholas, Shapiro, Oleg, Panaretou, Barry, Prodromou, Chrisostomos, Loh, Stewart N, Gutmann, David H, Bourboulia, Dimitra, Bratslavsky, Gennady, Wong, Michael, Mollapour, Mehdi
Publicado 2017

Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90

por Sager, Rebecca A., Woodford, Mark R., Backe, Sarah J., Makedon, Alan M., Baker-Williams, Alexander J., DiGregorio, Bryanna T., Loiselle, David R., Haystead, Timothy A., Zachara, Natasha E., Prodromou, Chrisostomos, Bourboulia, Dimitra, Schmidt, Laura S., Linehan, W. Marston, Bratslavsky, Gennady, Mollapour, Mehdi
Publicado 2019