Enhancing the sensitivity of the thymidine kinase assay by using DNA repair‐deficient human TK6 cells

por Ibrahim, Mahmoud Abdelghany, Yasui, Manabu, Saha, Liton Kumar, Sasanuma, Hiroyuki, Honma, Masamitsu, Takeda, Shunichi
Publicado 2020

Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes

por Saha, Liton Kumar, Saha, Sourav, Yang, Xi, Huang, Shar-yin Naomi, Sun, Yilun, Jo, Ukhyun, Pommier, Yves
Publicado 2023

The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes

por Saha, Sourav, Huang, Shar-yin Naomi, Yang, Xi, Saha, Liton Kumar, Sun, Yilun, Khandagale, Prashant, Jenkins, Lisa M., Pommier, Yves
Publicado 2023

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

por Jo, Ukhyun, Murai, Yasuhisa, Chakka, Sirisha, Chen, Lu, Cheng, Ken, Murai, Junko, Saha, Liton Kumar, Miller Jenkins, Lisa M., Pommier, Yves
Publicado 2021

UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks

por Akagawa, Remi, Trinh, Hai Thanh, Saha, Liton Kumar, Tsuda, Masataka, Hirota, Kouji, Yamada, Shintaro, Shibata, Atsushi, Kanemaki, Masato T., Nakada, Shinichiro, Takeda, Shunichi, Sasanuma, Hiroyuki
Publicado 2020

A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage

por Li, Jianfeng, Beiser, Alison, Dey, Nupur B, Takeda, Shunichi, Saha, Liton Kumar, Hirota, Kouji, Parker, L Lynette, Carter, Mariah, Arrieta, Martha I, Sobol, Robert W
Publicado 2022

Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents

por Jo, Ukhyun, Senatorov, Ilya S., Zimmermann, Astrid, Saha, Liton Kumar, Murai, Yasuhisa, Kim, Se Hyun, Rajapakse, Vinodh N., Elloumi, Fathi, Takahashi, Nobuyuki, Schultz, Christopher W., Thomas, Anish, Zenke, Frank T., Pommier, Yves
Publicado 2021

ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer

por Schultz, Christopher W, Zhang, Yang, Elmeskini, Rajaa, Zimmermann, Astrid, Fu, Haiqing, Murai, Yasuhisa, Wangsa, Darawalee, Kumar, Suresh, Takahashi, Nobuyuki, Atkinson, Devon, Saha, Liton Kumar, Lee, Chien‐Fei, Elenbaas, Brian, Desai, Parth, Sebastian, Robin, Sharma, Ajit Kumar, Abel, Melissa, Schroeder, Brett, Krishnamurthy, Manan, Kumar, Rajesh, Roper, Nitin, Aladjem, Mirit, Zenke, Frank T, Ohler, Zoe Weaver, Pommier, Yves, Thomas, Anish
Publicado 2023