The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism

por Xu, Yan, Robev, Dorothea, Saha, Nayanendu, Wang, Bingcheng, Dalva, Matthew B., Xu, Kai, Himanen, Juha P., Nikolov, Dimitar B.
Publicado 2021

Inhibitory monoclonal antibody targeting ADAM17 expressed on cancer cells

por Saha, Nayanendu, Xu, Kai, Zhu, Zhongyu, Robev, Dorothea, Kalidindi, Teja, Xu, Yan, Himanen, Juha, de Stanchina, Elisa, Pillarsetty, Naga Vara Kishore, Dimitrov, Dimiter S, Nikolov, Dimitar B
Publicado 2021

Preferential Antibody and Drug Conjugate Targeting of the ADAM10 Metalloprotease in Tumours

por Yan, Hengkang, Vail, Mary E., Hii, Linda, Guo, Nancy, McMurrick, Paul J., Oliva, Karen, Wilkins, Simon, Saha, Nayanendu, Nikolov, Dimitar B., Lee, Fook-Thean, Scott, Andrew M., Janes, Peter W.
Publicado 2022

Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells

por Saha, Nayanendu, Baek, Du-San, Mendoza, Rachelle P., Robev, Dorothea, Xu, Yan, Goldgur, Yehuda, De La Cruz, M. Jason, de Stanchina, Elisa, Janes, Peter W., Xu, Kai, Dimitrov, Dimiter S., Nikolov, Dimitar B.
Publicado 2023

Ephrin-A1 and the sheddase ADAM12 are upregulated in COVID-19

por Mendoza, Rachelle, Saha, Nayanendu, Momeni, Amir, Gabutan, Elmer, Alawad, Mouyed, Dehghani, Amir, Diks, John, Lin, Bo, Wang, Donghai, Alshal, Mohamed, Fyke, William, Wang, Bingcheng, Himanen, Juha P., Premsrirut, Prem, Nikolov, Dimitar B.
Publicado 2021

An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth

por Atapattu, Lakmali, Saha, Nayanendu, Chheang, Chanly, Eissman, Moritz F., Xu, Kai, Vail, Mary E., Hii, Linda, Llerena, Carmen, Liu, Zhanqi, Horvay, Katja, Abud, Helen E., Kusebauch, Ulrike, Moritz, Robert L., Ding, Bi-Sen, Cao, Zhongwei, Rafii, Shahin, Ernst, Matthias, Scott, Andrew M., Nikolov, Dimitar B., Lackmann, Martin, Janes, Peter W.
Publicado 2016