Discovery of N-benzyl hydroxypyridone carboxamides as a novel and potent antiviral chemotype against human cytomegalovirus (HCMV)

por Senaweera, Sameera, Edwards, Tiffany C., Kankanala, Jayakanth, Wang, Yan, Sahani, Rajkumar Lalji, Xie, Jiashu, Geraghty, Robert J., Wang, Zhengqiang
Publicado 2022

Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability

por Wang, Lei, Casey, Mary C., Vernekar, Sanjeev Kumar V., Sahani, Rajkumar Lalji, Kirby, Karen A., Du, Haijuan, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Publicado 2021

Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules

por Vernekar, Sanjeev Kumar V., Sahani, Rajkumar Lalji, Casey, Mary C., Kankanala, Jayakanth, Wang, Lei, Kirby, Karen A., Du, Haijuan, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Publicado 2020

Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74

por Sahani, Rajkumar Lalji, Diana-Rivero, Raquel, Vernekar, Sanjeev Kumar V., Wang, Lei, Du, Haijuan, Zhang, Huanchun, Castaner, Andres Emanuelli, Casey, Mary C., Kirby, Karen A., Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Publicado 2021