Anti-angiogenic Targets: Angiopoietin and Angiopoietin Receptors

por Kiss, Elina A., Saharinen, Pipsa
Publicado 2019

Angiopoietin–Tie signalling in the cardiovascular and lymphatic systems

por Eklund, Lauri, Kangas, Jaakko, Saharinen, Pipsa
Publicado 2016

The TIE Receptor Family

por Saharinen, Pipsa, Jeltsch, Michael, Santoyo, Mayte M., Leppänen, Veli-Matti, Alitalo, Kari
Publicado 2015

VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption

por Nurmi, Harri, Saharinen, Pipsa, Zarkada, Georgia, Zheng, Wei, Robciuc, Marius R, Alitalo, Kari
Publicado 2015

Association of Angiopoietin-2 and Ki-67 Expression with Vascular Density and Sunitinib Response in Metastatic Renal Cell Carcinoma

por Rautiola, Juhana, Lampinen, Anita, Mirtti, Tuomas, Ristimäki, Ari, Joensuu, Heikki, Bono, Petri, Saharinen, Pipsa
Publicado 2016

The possible dual role of Ang-2 in the prognosis of pancreatic cancer

por Roos-Mattila, Matilda, Kaprio, Tuomas, Mustonen, Harri, Hagström, Jaana, Saharinen, Pipsa, Haglund, Caj, Seppänen, Hanna
Publicado 2023

The Janus kinases (Jaks)

por Yamaoka, Kunihiro, Saharinen, Pipsa, Pesu, Marko, Holt, Vance ET, Silvennoinen, Olli, O'Shea, John J
Publicado 2004

Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity

por Gjini, Evisa, Hekking, Liesbeth H., Küchler, Axel, Saharinen, Pipsa, Wienholds, Erno, Post, Jan-Andries, Alitalo, Kari, Schulte-Merker, Stefan
Publicado 2011

Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2

por Saharinen, Pipsa, Kerkelä, Katja, Ekman, Niklas, Marron, Marie, Brindle, Nicholas, Lee, Gyun Min, Augustin, Hellmut, Koh, Gou Young, Alitalo, Kari
Publicado 2005

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi’s sarcoma studies

por Tuohinto, Krista, DiMaio, Terri A., Kiss, Elina A., Laakkonen, Pirjo, Saharinen, Pipsa, Karnezis, Tara, Lagunoff, Michael, Ojala, Päivi M.
Publicado 2023

Endothelial destabilization by angiopoietin-2 via integrin β1 activation

por Hakanpaa, Laura, Sipila, Tuomas, Leppanen, Veli-Matti, Gautam, Prson, Nurmi, Harri, Jacquemet, Guillaume, Eklund, Lauri, Ivaska, Johanna, Alitalo, Kari, Saharinen, Pipsa
Publicado 2015

Targeting β1-integrin inhibits vascular leakage in endotoxemia

por Hakanpaa, Laura, Kiss, Elina A., Jacquemet, Guillaume, Miinalainen, Ilkka, Lerche, Martina, Guzmán, Camilo, Mervaala, Eero, Eklund, Lauri, Ivaska, Johanna, Saharinen, Pipsa
Publicado 2018

Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis

por Holopainen, Tanja, Saharinen, Pipsa, D’Amico, Gabriela, Lampinen, Anita, Eklund, Lauri, Sormunen, Raija, Anisimov, Andrey, Zarkada, Georgia, Lohela, Marja, Heloterä, Hanna, Tammela, Tuomas, Benjamin, Laura E., Ylä-Herttuala, Seppo, Leow, Ching Ching, Koh, Gou Young, Alitalo, Kari
Publicado 2012

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation

por Pekkonen, Pirita, Alve, Sanni, Balistreri, Giuseppe, Gramolelli, Silvia, Tatti-Bugaeva, Olga, Paatero, Ilkka, Niiranen, Otso, Tuohinto, Krista, Perälä, Nina, Taiwo, Adewale, Zinovkina, Nadezhda, Repo, Pauliina, Icay, Katherine, Ivaska, Johanna, Saharinen, Pipsa, Hautaniemi, Sampsa, Lehti, Kaisa, Ojala, Päivi M
Publicado 2018

Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression

por Korhonen, Emilia A., Murtomäki, Aino, Jha, Sawan Kumar, Anisimov, Andrey, Pink, Anne, Zhang, Yan, Stritt, Simon, Liaqat, Inam, Stanczuk, Lukas, Alderfer, Laura, Sun, Zhiliang, Kapiainen, Emmi, Singh, Abhishek, Sultan, Ibrahim, Lantta, Anni, Leppänen, Veli-Matti, Eklund, Lauri, He, Yulong, Augustin, Hellmut G., Vaahtomeri, Kari, Saharinen, Pipsa, Mäkinen, Taija, Alitalo, Kari
Publicado 2022