Telomeres and sirtuins: at the end we meet again

por Amano, Hisayuki, Sahin, Ergun
Publicado 2019

Fructose Causes Liver Damage, Polyploidy, and Dysplasia in the Setting of Short Telomeres and p53 Loss

por Chronowski, Christopher, Akhanov, Viktor, Chan, Doug, Catic, Andre, Finegold, Milton, Sahin, Ergün
Publicado 2021

Imaging-Based Screening of Deubiquitinating Proteases Identifies Otubain-1 as a Stabilizer of c-MYC

por Moree, Shannon E., Maneix, Laure, Iakova, Polina, Stossi, Fabio, Sahin, Ergun, Catic, Andre
Publicado 2022

The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes

por Sweeney, Melanie A., Iakova, Polina, Maneix, Laure, Shih, Fu-Yuan, Cho, Hannah E., Sahin, Ergun, Catic, Andre
Publicado 2020

The Mitochondrial Protease LonP1 Promotes Proteasome Inhibitor Resistance in Multiple Myeloma

por Maneix, Laure, Sweeney, Melanie A., Lee, Sukyeong, Iakova, Polina, Moree, Shannon E., Sahin, Ergun, Lulla, Premal, Yellapragada, Sarvari V., Tsai, Francis T. F., Catic, Andre
Publicado 2021

LKB1 regulates quiescence and metabolic homeostasis of hematopoietic stem cells

por Gan, Boyi, Hu, Jian, Jiang, Shan, Liu, Yingchun, Sahin, Ergün, Zhuang, Li, Fletcher-Sananikone, Eliot, Colla, Simona, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Publicado 2010

Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation

por Maneix, Laure, Iakova, Polina, Moree, Shannon E., Hsu, Joanne I., Mistry, Ragini M., Stossi, Fabio, Lulla, Premal, Sun, Zheng, Sahin, Ergun, Yellapragada, Sarvari V., Catic, André
Publicado 2022

Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells

por Freise, Christian, Lee, Hyunho, Chronowski, Christopher, Chan, Doug, Cziomer, Jessica, Rühl, Martin, Dagdelen, Tarkan, Lösekann, Maik, Erben, Ulrike, Catic, Andre, Tegge, Werner, Schuppan, Detlef, Somasundaram, Rajan, Sahin, Ergun
Publicado 2021

Telomerase reactivation reverses tissue degeneration in aged telomerase deficient mice

por Jaskelioff, Mariela, Muller, Florian L., Paik, Ji-Hye, Thomas, Emily, Jiang, Shan, Adams, Andrew, Sahin, Ergun, Kost-Alimova, Maria, Protopopov, Alexei, Cadiñanos, Juan, Horner, James W., Maratos-Flier, Eleftheria, DePinho, Ronald A.
Publicado 2010

DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer

por Matsunuma, Ryoichi, Chan, Doug W., Kim, Beom-Jun, Singh, Purba, Han, Airi, Saltzman, Alexander B., Cheng, Chonghui, Lei, Jonathan T., Wang, Junkai, Roberto da Silva, Leonardo, Sahin, Ergun, Leng, Mei, Fan, Cheng, Perou, Charles M., Malovannaya, Anna, Ellis, Matthew J.
Publicado 2018

A chemical chaperone improves muscle function in mice with a RyR1 mutation

por Lee, Chang Seok, Hanna, Amy D., Wang, Hui, Dagnino-Acosta, Adan, Joshi, Aditya D., Knoblauch, Mark, Xia, Yan, Georgiou, Dimitra K., Xu, Jianjun, Long, Cheng, Amano, Hisayuki, Reynolds, Corey, Dong, Keke, Martin, John C., Lagor, William R., Rodney, George G., Sahin, Ergun, Sewry, Caroline, Hamilton, Susan L.
Publicado 2017

Passenger Deletions Generate Therapeutic Vulnerabilities in Cancer

por Muller, Florian L., Colla, Simona, Aquilanti, Elisa, Manzo, Veronica, Genovese, Giannicola, Lee, Jaclyn, Eisenson, Dan, Narurkar, Rujuta, Deng, Pingna, Nezi, Luigi, Lee, Michelle, Hu, Baoli, Hu, Jian, Sahin, Ergun, Ong, Derrick, Fletcher-Sananikone, Eliot, Ho, Dennis, Kwong, Lawrence, Brennan, Cameron, Wang, Y. Alan, Chin, Lynda, DePinho, Ronald A.
Publicado 2012

Hematopoiesis under telomere attrition at the single-cell resolution

por Thongon, Natthakan, Ma, Feiyang, Santoni, Andrea, Marchesini, Matteo, Fiorini, Elena, Rose, Ashley, Adema, Vera, Ganan-Gomez, Irene, Groarke, Emma M., Gutierrez-Rodrigues, Fernanda, Chen, Shuaitong, Lockyer, Pamela, Schneider, Sarah, Bueso-Ramos, Carlos, Montalban-Bravo, Guillermo, Class, Caleb A., Soltysiak, Kelly A., Pellegrini, Matteo, Sahin, Ergun, Bertuch, Alison A., DiNardo, Courtney D., Garcia-Manero, Guillermo, Young, Neal S., Dwyer, Karen, Colla, Simona
Publicado 2021