Genetic risk in chronic pancreatitis: the misfolding-dependent pathway

por Sahin-Tóth, Miklós
Publicado 2017

Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway

por Hegyi, Eszter, Sahin-Tóth, Miklós
Publicado 2017

Trypsinogen isoforms in the ferret pancreas

por Hegyi, Eszter, Sahin-Tóth, Miklós
Publicado 2018

A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation

por Geisz, Andrea, Sahin-Tóth, Miklós
Publicado 2018

Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin B

por Demcsák, Alexandra, Geisz, Andrea, Sahin-Tóth, Miklós
Publicado 2019

Lipotoxicity and Cytokine Storm in Severe Acute Pancreatitis and COVID-19

por Hegyi, Péter, Szakács, Zsolt, Sahin-Tóth, Miklós
Publicado 2020

Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice

por Mosztbacher, Dóra, Jancsó, Zsanett, Sahin-Tóth, Miklós
Publicado 2020

Misfolding-induced chronic pancreatitis in CPA1 N256K mutant mice is unaffected by global deletion of Ddit3/Chop

por Németh, Balázs Csaba, Demcsák, Alexandra, Geisz, Andrea, Sahin-Tóth, Miklós
Publicado 2022

Tyrosine Sulfation of Human Trypsin Steers S2’ Subsite Selectivity towards Basic Amino Acids

por Szabó, András, Salameh, Moh’d A., Ludwig, Maren, Radisky, Evette S., Sahin-Tóth, Miklós
Publicado 2014

Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis

por Szabó, András, Toldi, Vanda, Gazda, Lívia Diána, Demcsák, Alexandra, Tőzsér, József, Sahin-Tóth, Miklós
Publicado 2021

Bicarbonate defective CFTR variants increase risk for chronic pancreatitis: A meta-analysis

por Berke, Gergő, Gede, Noémi, Szadai, Letícia, Ocskay, Klementina, Hegyi, Péter, Sahin-Tóth, Miklós, Hegyi, Eszter
Publicado 2022

Preclinical testing of dabigatran in trypsin-dependent pancreatitis

por Pesei, Zsófia Gabriella, Jancsó, Zsanett, Demcsák, Alexandra, Németh, Balázs Csaba, Vajda, Sandor, Sahin-Tóth, Miklós
Publicado 2022

Novel Pathogenic PRSS1 Variant p.Glu190Lys in a Case of Chronic Pancreatitis

por Jancsó, Zsanett, Oracz, Grzegorz, Kujko, Aleksandra Anna, Kolodziejczyk, Eliwira, Radisky, Evette S., Rygiel, Agnieszka Magdalena, Sahin-Tóth, Miklós
Publicado 2019

The common truncation variant in pancreatic lipase related protein 2 (PNLIPRP2) is expressed poorly and does not alter risk for chronic pancreatitis

por Németh, Balázs Csaba, Pesei, Zsófia Gabriella, Hegyi, Eszter, Szücs, Ákos, Szentesi, Andrea, Hegyi, Péter, Lowe, Mark E., Sahin-Tóth, Miklós
Publicado 2018

Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic...

por Párniczky, Andrea, Hegyi, Eszter, Tóth, Anna Zsófia, Szücs, Ákos, Szentesi, Andrea, Vincze, Áron, Izbéki, Ferenc, Németh, Balázs Csaba, Hegyi, Péter, Sahin-Tóth, Miklós
Publicado 2016

Risk of chronic pancreatitis in carriers of loss-of-function CTRC variants: A meta-analysis

por Takáts, Amanda, Berke, Gergő, Gede, Noémi, Németh, Balázs Csaba, Witt, Heiko, Głuszek, Stanisław, Rygiel, Agnieszka Magdalena, Hegyi, Péter, Sahin-Tóth, Miklós, Hegyi, Eszter
Publicado 2022

Novel p.G250A Mutation Associated with Chronic Pancreatitis Highlights Misfolding-Prone Region in Carboxypeptidase A1 (CPA1)

por Sándor, Máté, Thiel, Franziska G., Schmid, Margit, Demcsák, Alexandra, Morales Granda, Nataly C., Németh, Balázs Csaba, Vajda, Sandor, Hoerning, André, Sahin-Tóth, Miklós
Publicado 2022

Pancreatitis-Associated Genes and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis

por Cazacu, Irina Mihaela, Farkas, Nelli, Garami, András, Balaskó, Márta, Mosdósi, Bernadett, Alizadeh, Hussain, Gyöngyi, Zoltán, Rakonczay, Zoltán, Vigh, Éva, Habon, Tamás, Czopf, László, Lazarescu, Marilena Alina, Erőss, Bálint, Sahin-Tóth, Miklós, Hegyi, Péter
Publicado 2018

Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers

por Mehner, Christine, Oberg, Ann L., Kalli, Kimberly R., Nassar, Aziza, Hockla, Alexandra, Pendlebury, Devon, Cichon, Magdalena A., Goergen, Krista M., Maurer, Matthew J., Goode, Ellen L., Keeney, Gary L., Jatoi, Aminah, Sahin-Tóth, Miklós, Copland, John A., Radisky, Derek C., Radisky, Evette S.
Publicado 2015

Observational longitudinal multicentre investigation of acute pancreatitis (GOULASH PLUS): follow-up of the GOULASH study, protocol

por Mikó, Alexandra, Erőss, Bálint, Sarlós, Patrícia, Hegyi Jr, Péter, Márta, Katalin, Pécsi, Dániel, Vincze, Áron, Bódis, Beáta, Nemes, Orsolya, Faluhelyi, Nándor, Farkas, Orsolya, Papp, Róbert, Kelemen, Dezső, Szentesi, Andrea, Hegyi, Eszter, Papp, Mária, Czakó, László, Izbéki, Ferenc, Gajdán, László, Novák, János, Sahin-Tóth, Miklós, Lerch, Markus M, Neoptolemos, John, Petersen, Ole H, Hegyi, Péter
Publicado 2019