Design and Antiproliferative Evaluation of Novel Sulfanilamide Derivatives as Potential Tubulin Polymerization Inhibitors

por Fu, Dong-Jun, Liu, Ji-Feng, Zhao, Ruo-Han, Li, Jia-Huan, Zhang, Sai-Yang, Zhang, Yan-Bing
Publicado 2017

Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5-a]pyrimidine Indole Derivatives against Gastric Cancer Cells MGC-803 via the Suppression of ERK Signaling Pathway

por Yu, Guang-Xi, Hu, Ying, Zhang, Wei-Xin, Tian, Xin-Yi, Zhang, Sai-Yang, Zhang, Yan, Yuan, Shuo, Song, Jian
Publicado 2022

Design, Synthesis and Structure-Activity Relationships of Novel Chalcone-1,2,3-triazole-azole Derivates as Antiproliferative Agents

por Zhang, Sai-Yang, Fu, Dong-Jun, Yue, Xiao-Xin, Liu, Ying-Chao, Song, Jian, Sun, Hui-Hui, Liu, Hong-Min, Zhang, Yan-Bing
Publicado 2016

Zingerone attenuates aortic banding‐induced cardiac remodelling via activating the eNOS/Nrf2 pathway

por Liu, Chen, Wu, Qing-Qing, Cai, Zhu-Lan, Xie, Sai-Yang, Duan, Ming-Xia, Xie, Qing-Wen, Yuan, Yuan, Deng, Wei, Tang, Qi‐Zhu
Publicado 2019

Discovery of Novel Diarylamide N-Containing Heterocyclic Derivatives as New Tubulin Polymerization Inhibitors with Anti-Cancer Activity

por Liu, Xu, Pang, Xiao-Jing, Liu, Yuan, Liu, Wen-Bo, Li, Yin-Ru, Yu, Guang-Xi, Zhang, Yan-Bing, Song, Jian, Zhang, Sai-Yang
Publicado 2021

A Review of the Regulatory Mechanisms of N-Myc on Cell Cycle

por Li, Hong-Li, Dong, Lu-Lu, Jin, Min-Jie, Li, Qian-Yu, Wang, Xiao, Jia, Mei-Qi, Song, Jian, Zhang, Sai-Yang, Yuan, Shuo
Publicado 2023

Discovery of novel arylamide derivatives containing piperazine moiety as inhibitors of tubulin polymerisation with potent liver cancer inhibitory activity

por Shi, Xiao-Yi, Jiao, Huang, Zhang, Jia-Kai, Tian, Xin-Yi, Guo, Dan-Feng, Gao, Jie, Jia, Mei-Qi, Song, Jian, Zhang, Sai-Yang, Fu, Xiang-Jing, Tang, Hong-Wei
Publicado 2023

Drug Discovery Targeting Focal Adhesion Kinase (FAK) as a Promising Cancer Therapy

por Pang, Xiao-Jing, Liu, Xiu-Juan, Liu, Yuan, Liu, Wen-Bo, Li, Yin-Ru, Yu, Guang-Xi, Tian, Xin-Yi, Zhang, Yan-Bing, Song, Jian, Jin, Cheng-Yun, Zhang, Sai-Yang
Publicado 2021

Discovery of N-aryl sulphonamide-quinazoline derivatives as anti-gastric cancer agents in vitro and in vivo via activating the Hippo signalling pathway

por Niu, Jin-Bo, Hua, Chun-Quan, Liu, Yuan, Yu, Guang-Xi, Yang, Jia-Jia, Li, Yin-Ru, Zhang, Yan-Bing, Qi, Ying-Qiu, Song, Jian, Jin, Cheng-Yun, Zhang, Sai-Yang
Publicado 2021

Design, Synthesis, and Anticancer Activity Studies of Novel Quinoline-Chalcone Derivatives

por Guan, Yong-Feng, Liu, Xiu-Juan, Yuan, Xin-Ying, Liu, Wen-Bo, Li, Yin-Ru, Yu, Guang-Xi, Tian, Xin-Yi, Zhang, Yan-Bing, Song, Jian, Li, Wen, Zhang, Sai-Yang
Publicado 2021

Mechanism-Based Pharmacokinetic Model for the Deglycosylation Kinetics of 20(S)-Ginsenosides Rh2

por Ren, Hong-can, Sun, Jian-guo, A, Ji-ye, Gu, Sheng-hua, Shi, Jian, Shao, Feng, Ai, Hua, Zhang, Jing-wei, Peng, Ying, Yan, Bei, Huang, Qing, Liu, Lin-sheng, Sai, Yang, Wang, Guang-ji, Yang, Cheng-guang
Publicado 2022

Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor

por Cai, Yu, Yu, Jun, Ren, Ping, He, Jianlin, Wu, Zhipeng, Xiao, Kun, Jia, Hong, Wang, Jian, Sai, Yang, Dai, Guangxiu, Li, Xiong, Su, Weiguo, Ngo, Karen, Castro, Glenda, Acton, Paul D., Fung‐Leung, Wai‐Ping, Edwards, James P., Venable, Jennifer, Rao, Tadimeti S.
Publicado 2020

Synthesis and Biological Evaluation of Amino Chalcone Derivatives as Antiproliferative Agents

por Lu, Chao-Fan, Wang, Sheng-Hui, Pang, Xiao-Jing, Zhu, Ting, Li, Hong-Li, Li, Qing-Rong, Li, Qian-Yu, Gu, Yu-Fan, Mu, Zhao-Yang, Jin, Min-Jie, Li, Yin-Ru, Hu, Yang-Yang, Zhang, Yan-Bing, Song, Jian, Zhang, Sai-Yang
Publicado 2020

Sulfatinib, a novel kinase inhibitor, in patients with advanced solid tumors: results from a phase I study

por Xu, Jian Ming, Wang, Yan, Chen, Yu Ling, Jia, Ru, Li, Jie, Gong, Ji Fang, Li, Jing, Qi, Chuan, Hua, Ye, Tan, Cui Rong, Wang, Jian, Li, Ke, Sai, Yang, Zhou, Feng, Ren, Yong Xin, Qing, Wei Guo, Jia, Hong, Su, Wei Guo, Shen, Lin
Publicado 2017

Structure-Activity Relationship Studies of β-Lactam-azide Analogues as Orally Active Antitumor Agents Targeting the Tubulin Colchicine Site

por Fu, Dong-Jun, Fu, Ling, Liu, Ying-Chao, Wang, Jun-Wei, Wang, Yu-Qing, Han, Bing-Kai, Li, Xiao-Rui, Zhang, Chuang, Li, Feng, Song, Jian, Zhao, Bing, Mao, Ruo-Wang, Zhao, Ruo-Han, Zhang, Sai-Yang, Zhang, Li, Zhang, Yan-Bing, Liu, Hong-Min
Publicado 2017