Blob-ology and biology of cryo-EM: an interview with Helen Saibil

por Saibil, Helen R.
Publicado 2017

The PDB and protein homeostasis: From chaperones to degradation and disaggregase machines

por Saibil, Helen R.
Publicado 2021

Cryo electron microscopy to determine the structure of macromolecular complexes

por Carroni, Marta, Saibil, Helen R.
Publicado 2016

ATP-Driven Molecular Chaperone Machines

por Clare, Daniel K, Saibil, Helen R
Publicado 2013

Prion aggregate structure in yeast cells is determined by the Hsp104-Hsp110 disaggregase machinery

por O’Driscoll, Jonathan, Clare, Daniel, Saibil, Helen
Publicado 2015

A national facility for biological cryo-electron microscopy

por Saibil, Helen R., Grünewald, Kay, Stuart, David I.
Publicado 2015

Pathogen–host reorganization during Chlamydia invasion revealed by cryo-electron tomography

por Nans, Andrea, Saibil, Helen R, Hayward, Richard D
Publicado 2014

Structure of a bacterial type III secretion system in contact with a host membrane in situ

por Nans, Andrea, Kudryashev, Mikhail, Saibil, Helen R., Hayward, Richard D.
Publicado 2015

Structural basis of ubiquitin‐independent PP1 complex disassembly by p97

por van den Boom, Johannes, Marini, Guendalina, Meyer, Hemmo, Saibil, Helen R
Publicado 2023

Chlamydiae Assemble a Pathogen Synapse to Hijack the Host Endoplasmic Reticulum

por Dumoux, Maud, Clare, Daniel K, Saibil, Helen R, Hayward, Richard D
Publicado 2012

Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor

por Deville, Célia, Franke, Kamila, Mogk, Axel, Bukau, Bernd, Saibil, Helen R.
Publicado 2019

Atypical AAA+ Subunit Packing Creates an Expanded Cavity for Disaggregation by the Protein-Remodeling Factor Hsp104

por Wendler, Petra, Shorter, James, Plisson, Celia, Cashikar, Anil G., Lindquist, Susan, Saibil, Helen R.
Publicado 2007

A two-domain folding intermediate of RuBisCO in complex with the GroEL chaperonin

por Natesh, Ramanathan, Clare, Daniel K., Farr, George W., Horwich, Arthur L., Saibil, Helen R.
Publicado 2018

Motor Mechanism for Protein Threading through Hsp104

por Wendler, Petra, Shorter, James, Snead, David, Plisson, Celia, Clare, Daniel K., Lindquist, Susan, Saibil, Helen R.
Publicado 2009

Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase

por Deville, Célia, Carroni, Marta, Franke, Kamila B., Topf, Maya, Bukau, Bernd, Mogk, Axel, Saibil, Helen R.
Publicado 2017

A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation

por Peskett, Thomas R., Rau, Frédérique, O’Driscoll, Jonathan, Patani, Rickie, Lowe, Alan R., Saibil, Helen R.
Publicado 2018

Topologies of a Substrate Protein Bound to the Chaperonin GroEL

por Elad, Nadav, Farr, George W., Clare, Daniel K., Orlova, Elena V., Horwich, Arthur L., Saibil, Helen R.
Publicado 2007

Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ

por Malet, Hélène, Canellas, Flavia, Sawa, Justyna, Yan, Jun, Thalassinos, Konstantinos, Ehrmann, Michael, Clausen, Tim, Saibil, Helen R
Publicado 2012

The pore conformation of lymphocyte perforin

por Ivanova, Marina E., Lukoyanova, Natalya, Malhotra, Sony, Topf, Maya, Trapani, Joseph A., Voskoboinik, Ilia, Saibil, Helen R.
Publicado 2022

A structural basis for prion strain diversity

por Manka, Szymon W., Wenborn, Adam, Betts, Jemma, Joiner, Susan, Saibil, Helen R., Collinge, John, Wadsworth, Jonathan D. F.
Publicado 2023