Metabolism of amyloid β peptide and pathogenesis of Alzheimer’s disease

por SAIDO, Takaomi C.
Publicado 2013

Dual roles for autophagy: Degradation and secretion of Alzheimer's disease Aβ peptide

por Nilsson, Per, Saido, Takaomi C
Publicado 2014

Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease

por Hashimoto, Shoko, Saido, Takaomi C.
Publicado 2018

Neuroinflammation in mouse models of Alzheimer's disease

por Saito, Takashi, Saido, Takaomi C.
Publicado 2018

Novel Quantitative Analyses of Spontaneous Synaptic Events in Cortical Pyramidal Cells Reveal Subtle Parvalbumin-Expressing Interneuron Dysfunction in a Knock-In Mouse Model of Alz...

por Chen, Lingxuan, Saito, Takashi, Saido, Takaomi C., Mody, Istvan
Publicado 2018

Analysis of Taste Sensitivities in App Knock-In Mouse Model of Alzheimer’s Disease

por Narukawa, Masataka, Takahashi, Suzuka, Saito, Takashi, Saido, Takaomi C., Misaka, Takumi
Publicado 2020

Distinct functional consequences of ECEL1/DINE missense mutations in the pathogenesis of congenital contracture disorders

por Nagata, Kenichi, Takahashi, Mika, Kiryu-Seo, Sumiko, Kiyama, Hiroshi, Saido, Takaomi C.
Publicado 2017

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

por Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Saido, Takaomi C., Iijima, Koichi M.
Publicado 2018

Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer’s disease

por Sakakibara, Yasufumi, Sekiya, Michiko, Saito, Takashi, Saido, Takaomi C., Iijima, Koichi M.
Publicado 2019

Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer’s disease brains

por Sharoar, Md Golam, Palko, Sarah, Ge, Yingying, Saido, Takaomi C., Yan, Riqiang
Publicado 2021

Microglia and CD206(+) border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease

por Wu, Xiaoting, Saito, Takashi, Saido, Takaomi C, Barron, Anna M, Ruedl, Christiane
Publicado 2021

CRISPR/dCas9-Dnmt3a-mediated targeted DNA methylation of APP rescues brain pathology in a mouse model of Alzheimer’s disease

por Park, Hanseul, Shin, Jaein, Kim, Yunkyung, Saito, Takashi, Saido, Takaomi C., Kim, Jongpil
Publicado 2022

Impaired sharp-wave ripple coordination between the medial entorhinal cortex and hippocampal CA1 of knock-in model of Alzheimer’s disease

por Funane, Tsukasa, Jun, Heechul, Sutoko, Stephanie, Saido, Takaomi C., Kandori, Akihiko, Igarashi, Kei M.
Publicado 2022

The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives

por Yoshimura, Rikuya, Miyasaka, Tomohiro, Funamoto, Satoru, Saito, Takashi, Saido, Takaomi C., Ikegawa, Masaya, Kakuda, Nobuto
Publicado 2023

Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse

por Benskey, Matthew J., Panoushek, Spencer, Saito, Takashi, Saido, Takaomi C., Grabinski, Tessa, Kanaan, Nicholas M.
Publicado 2023

Gene therapy in Alzheimer’s disease – potential for disease modification

por Nilsson, Per, Iwata, Nobuhisa, Muramatsu, Shin-ichi, Tjernberg, Lars O, Winblad, Bengt, Saido, Takaomi C
Publicado 2010

An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain

por Ni, Junjun, Wu, Zhou, Meng, Jie, Saito, Takashi, Saido, Takaomi C., Qing, Hong, Nakanishi, Hiroshi
Publicado 2019

Early Identification of Alzheimer's Disease in Mouse Models: Application of Deep Neural Network Algorithm to Cognitive Behavioral Parameters

por Sutoko, Stephanie, Masuda, Akira, Kandori, Akihiko, Sasaguri, Hiroki, Saito, Takashi, Saido, Takaomi C., Funane, Tsukasa
Publicado 2021

Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged App(NL-G-F/NL-G-F) mice

por Niikura, Ryo, Miyazaki, Tomoyuki, Takase, Kenkichi, Sasaguri, Hiroki, Saito, Takashi, Saido, Takaomi C., Goto, Takahisa
Publicado 2022

Evidence That β3 Integrin-Induced Rac Activation Involves the Calpain-Dependent Formation of Integrin Clusters That Are Distinct from the Focal Complexes and Focal Adhesions That F...

por Bialkowska, Katarzyna, Kulkarni, Sucheta, Du, Xiaoping, Goll, Darrel E., Saido, Takaomi C., Fox, Joan E.B.
Publicado 2000