Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center

por Saikatendu, Kumar Singh, Zhang, Xuejun, Kinch, Lisa, Leybourne, Matthew, Grishin, Nick V, Zhang, Hong
Publicado 2006

Discovery of Novel and Highly Selective Cyclopropane ALK Inhibitors through a Fragment-Assisted, Structure-Based Drug Design

por Fujimori, Ikuo, Wakabayashi, Takeshi, Murakami, Morio, Okabe, Atsutoshi, Ishii, Tsuyoshi, McGrath, Aaron, Zou, Hua, Saikatendu, Kumar Singh, Imoto, Hiroshi
Publicado 2020

Accelerating antiviral drug discovery: lessons from COVID-19

por von Delft, Annette, Hall, Matthew D., Kwong, Ann D., Purcell, Lisa A., Saikatendu, Kumar Singh, Schmitz, Uli, Tallarico, John A., Lee, Alpha A.
Publicado 2023

Structural Basis of Severe Acute Respiratory Syndrome Coronavirus ADP-Ribose-1″-Phosphate Dephosphorylation by a Conserved Domain of nsP3

por Saikatendu, Kumar Singh, Joseph, Jeremiah S., Subramanian, Vanitha, Clayton, Tom, Griffith, Mark, Moy, Kin, Velasquez, Jeffrey, Neuman, Benjamin W., Buchmeier, Michael J., Stevens, Raymond C., Kuhn, Peter
Publicado 2005

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

por Nakayama, Kazuhide, Szewczyk, Magdalena M., dela Sena, Carlo, Wu, Hong, Dong, Aiping, Zeng, Hong, Li, Fengling, de Freitas, Renato Ferreira, Eram, Mohammad S., Schapira, Matthieu, Baba, Yuji, Kunitomo, Mihoko, Cary, Douglas R., Tawada, Michiko, Ohashi, Akihiro, Imaeda, Yasuhiro, Saikatendu, Kumar Singh, Grimshaw, Charles E., Vedadi, Masoud, Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia, Kiba, Atsushi, Tomita, Daisuke, Brown, Peter J.
Publicado 2018

Target 2035 – an update on private sector contributions

por Ackloo, Suzanne, Antolin, Albert A., Bartolome, Jose Manuel, Beck, Hartmut, Bullock, Alex, Betz, Ulrich A. K., Böttcher, Jark, Brown, Peter J., Chaturvedi, Menorca, Crisp, Alisa, Daniels, Danette, Dreher, Jan, Edfeldt, Kristina, Edwards, Aled M., Egner, Ursula, Elkins, Jon, Fischer, Christian, Glendorf, Tine, Goldberg, Steven, Hartung, Ingo V., Hillisch, Alexander, Homan, Evert, Knapp, Stefan, Köster, Markus, Krämer, Oliver, Llaveria, Josep, Lessel, Uta, Lindemann, Sven, Linderoth, Lars, Matsui, Hisanori, Michel, Maurice, Montel, Florian, Mueller-Fahrnow, Anke, Müller, Susanne, Owen, Dafydd R., Saikatendu, Kumar Singh, Santhakumar, Vijayaratnam, Sanderson, Wendy, Scholten, Cora, Schapira, Matthieu, Sharma, Sujata, Shireman, Brock, Sundström, Michael, Todd, Matthew H., Tredup, Claudia, Venable, Jennifer, Willson, Timothy M., Arrowsmith, Cheryl H.
Publicado 2023

Target 2035 – update on the quest for a probe for every protein

por Müller, Susanne, Ackloo, Suzanne, Al Chawaf, Arij, Al-Lazikani, Bissan, Antolin, Albert, Baell, Jonathan B., Beck, Hartmut, Beedie, Shaunna, Betz, Ulrich A. K., Bezerra, Gustavo Arruda, Brennan, Paul E., Brown, David, Brown, Peter J., Bullock, Alex N., Carter, Adrian J., Chaikuad, Apirat, Chaineau, Mathilde, Ciulli, Alessio, Collins, Ian, Dreher, Jan, Drewry, David, Edfeldt, Kristina, Edwards, Aled M., Egner, Ursula, Frye, Stephen V., Fuchs, Stephen M., Hall, Matthew D., Hartung, Ingo V., Hillisch, Alexander, Hitchcock, Stephen H., Homan, Evert, Kannan, Natarajan, Kiefer, James R., Knapp, Stefan, Kostic, Milka, Kubicek, Stefan, Leach, Andrew R., Lindemann, Sven, Marsden, Brian D., Matsui, Hisanori, Meier, Jordan L., Merk, Daniel, Michel, Maurice, Morgan, Maxwell R., Mueller-Fahrnow, Anke, Owen, Dafydd R., Perry, Benjamin G., Rosenberg, Saul H., Saikatendu, Kumar Singh, Schapira, Matthieu, Scholten, Cora, Sharma, Sujata, Simeonov, Anton, Sundström, Michael, Superti-Furga, Giulio, Todd, Matthew H., Tredup, Claudia, Vedadi, Masoud, von Delft, Frank, Willson, Timothy M., Winter, Georg E., Workman, Paul, Arrowsmith, Cheryl H.
Publicado 2021