Mechanistic analysis of the enhanced RNAi activity by 6-mCEPh-purine at the 5′ end of the siRNA guide strand

por Brechin, Vincent, Shinohara, Fumikazu, Saito, Jun-ichi, Seitz, Hervé, Tomari, Yukihide
Publicado 2021

Structural insight into an anti-BRIL Fab as a G-protein-coupled receptor crystallization chaperone

por Miyagi, Hikaru, Suzuki, Michihiko, Yasunaga, Mai, Asada, Hidetsugu, Iwata, So, Saito, Jun-ichi
Publicado 2023

Structure-guided screening strategy combining surface plasmon resonance with nuclear magnetic resonance for identification of small-molecule Argonaute 2 inhibitors

por Harumoto, Toshimasa, Sato, Atsuko, Takayama, Yuki, Miyagi, Hikaru, Saito, Jun-ichi, Shinohara, Fumikazu
Publicado 2020

The discovery of a new antibody for BRIL-fused GPCR structure determination

por Miyagi, Hikaru, Asada, Hidetsugu, Suzuki, Michihiko, Takahashi, Yuichi, Yasunaga, Mai, Suno, Chiyo, Iwata, So, Saito, Jun-ichi
Publicado 2020

Radio-sensitization effect of an mTOR inhibitor, temsirolimus, on lung adenocarcinoma A549 cells under normoxic and hypoxic conditions

por Ushijima, Hiroki, Suzuki, Yoshiyuki, Oike, Takahiro, Komachi, Mayumi, Yoshimoto, Yuya, Ando, Ken, Okonogi, Noriyuki, Sato, Hiro, Noda, Shin-ei, Saito, Jun-ichi, Nakano, Takashi
Publicado 2015

siRNA potency enhancement via chemical modifications of nucleotide bases at the 5′-end of the siRNA guide strand

por Shinohara, Fumikazu, Oashi, Taiji, Harumoto, Toshimasa, Nishikawa, Tomoyuki, Takayama, Yuki, Miyagi, Hikaru, Takahashi, Yuichi, Nakajima, Takahiro, Sawada, Takashi, Koda, Yasuo, Makino, Asana, Sato, Atsuko, Hamaguchi, Kaori, Suzuki, Michihiko, Yamamoto, Junichiro, Tomari, Yukihide, Saito, Jun-Ichi
Publicado 2021