Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells

por Sajesh, Babu V., McManus, Kirk J.
Publicado 2015

Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells

por Sajesh, Babu V, Lichtensztejn, Zelda, McManus, Kirk J
Publicado 2013

Synthetic Genetic Targeting of Genome Instability in Cancer

por Sajesh, Babu V., Guppy, Brent J., McManus, Kirk J.
Publicado 2013

Synthetic Lethal Targeting of Superoxide Dismutase 1 Selectively Kills RAD54B-Deficient Colorectal Cancer Cells

por Sajesh, Babu V., Bailey, Melanie, Lichtensztejn, Zelda, Hieter, Philip, McManus, Kirk J.
Publicado 2013

SONIC HEDGEHOG (SHH) PROMOTES BLOOD-BRAIN BARRIER (BBB) INTEGRITY IN DIFFUSE MIDLINE GLIOMA OF THE PONS

por Line, Stacey, Sajesh, Babu V, Yathindranath, Vinith, On, Nog H, Miller, Donald W, Vanan, Magimairajan Issai
Publicado 2023

Dysregulation of neuroprotective astrocytes, a spectrum of microglial activation states, and altered hippocampal neurogenesis are revealed by single-cell RNA sequencing in prion di...

por Slota, Jessy A., Sajesh, Babu V., Frost, Kathy F., Medina, Sarah J., Booth, Stephanie A.
Publicado 2022

An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

por van Pel, Derek M., Barrett, Irene J., Shimizu, Yoko, Sajesh, Babu V., Guppy, Brent J., Pfeifer, Tom, McManus, Kirk J., Hieter, Philip
Publicado 2013

Correction: An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

por van Pel, Derek M., Barrett, Irene J., Shimizu, Yoko, Sajesh, Babu V., Guppy, Brent J., Pfeifer, Tom, McManus, Kirk J., Hieter, Philip
Publicado 2013

Spermidine/Spermine N1-Acetyltransferase 1 (SAT1)—A Potential Gene Target for Selective Sensitization of Glioblastoma Cells Using an Ionizable Lipid Nanoparticle to Deliver siRNA

por Yathindranath, Vinith, Safa, Nura, Sajesh, Babu V., Schwinghamer, Kelly, Vanan, Magimairajan Issai, Bux, Rashid, Sitar, Daniel S., Pitz, Marshall, Siahaan, Teruna J., Miller, Donald W.
Publicado 2022

Non-Productive Infection of Glial Cells with SARS-CoV-2 in Hamster Organotypic Cerebellar Slice Cultures

por Lamoureux, Lise, Sajesh, Babu, Slota, Jessy A., Medina, Sarah J., Mayor, Matthew, Frost, Kathy L., Warner, Bryce, Manguiat, Kathy, Wood, Heidi, Kobasa, Darwyn, Booth, Stephanie A.
Publicado 2022

Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors

por Sajesh, Babu V., On, Ngoc H., Omar, Refaat, Alrushaid, Samaa, Kopec, Brian M., Wang, Wei-Guang, Sun, Han-Dong, Lillico, Ryan, Lakowski, Ted M., Siahaan, Teruna J., Davies, Neal M., Puno, Pema-Tenzin, Vanan, Magimairajan Issai, Miller, Donald W.
Publicado 2019

MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus

por Kozak, Robert A., Majer, Anna, Biondi, Mia J., Medina, Sarah J., Goneau, Lee W., Sajesh, Babu V., Slota, Jessy A., Zubach, Vanessa, Severini, Alberto, Safronetz, David, Hiebert, Shannon L., Beniac, Daniel R., Booth, Timothy F., Booth, Stephanie A., Kobinger, Gary P.
Publicado 2017

Single Immunization with Recombinant ACAM2000 Vaccinia Viruses Expressing the Spike and the Nucleocapsid Proteins Protects Hamsters against SARS-CoV-2-Caused Clinical Disease

por Deschambault, Yvon, Lynch, Jessie, Warner, Bryce, Tierney, Kevin, Huynh, Denise, Vendramelli, Robert, Tailor, Nikesh, Frost, Kathy, Sajesh, Babu, LeBlanc, Kyle, Layne, Christine, Lin, Lisa, Tamming, Levi, Beniac, Daniel, Booth, Stephanie, Carpenter, Michael, Safronetz, David, Li, Xuguang, Kobasa, Darwyn, Cao, Jingxin
Publicado 2022