Cerebral metabolism in a mouse model of Alzheimer’s disease characterized by two-photon fluorescence lifetime microscopy of intrinsic NADH

por Gómez, Carlos A., Fu, Buyin, Sakadžić, Sava, Yaseen, Mohammad A.
Publicado 2018

Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation

por Li, Baoqiang, Lu, Xuecong, Moeini, Mohammad, Sakadžić, Sava, Thorin, Eric, Lesage, Frederic
Publicado 2019

Microstructural characterization of myocardial infarction with optical coherence tractography and two‐photon microscopy

por Goergen, Craig J., Chen, Howard H., Sakadžić, Sava, Srinivasan, Vivek J., Sosnovik, David E.
Publicado 2016

Interferometric diffuse correlation spectroscopy improves measurements at long source–detector separation and low photon count rate

por Robinson, Mitchell B., Boas, David A., Sakadzic, Sava, Franceschini, Maria Angela, Carp, Stefan A.
Publicado 2020

In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH

por Yaseen, Mohammad A., Sakadžić, Sava, Wu, Weicheng, Becker, Wolfgang, Kasischke, Karl A., Boas, David A.
Publicado 2013

Modeling of Cerebral Oxygen Transport Based on In vivo Microscopic Imaging of Microvascular Network Structure, Blood Flow, and Oxygenation

por Gagnon, Louis, Smith, Amy F., Boas, David A., Devor, Anna, Secomb, Timothy W., Sakadžić, Sava
Publicado 2016

Spatially resolved estimation of metabolic oxygen consumption from optical measurements in cortex

por Sætra, Marte J., Solbrå, Andreas V., Devor, Anna, Sakadžić, Sava, Dale, Anders M., Einevoll, Gaute T.
Publicado 2020

Quantitative cerebral blood flow with Optical Coherence Tomography

por Srinivasan, Vivek J., Sakadžić, Sava, Gorczynska, Iwona, Ruvinskaya, Svetlana, Wu, Weicheng, Fujimoto, James G., Boas, David A.
Publicado 2010

Due to intravascular multiple sequential scattering, Diffuse Correlation Spectroscopy of tissue primarily measures relative red blood cell motion within vessels

por Carp, Stefan A., Roche-Labarbe, Nadàege, Franceschini, Maria-Angela, Srinivasan, Vivek J., Sakadžić, Sava, Boas, David A.
Publicado 2011

Phasor analysis of NADH FLIM identifies pharmacological disruptions to mitochondrial metabolic processes in the rodent cerebral cortex

por Gómez, Carlos A., Sutin, Jason, Wu, Weicheng, Fu, Buyin, Uhlirova, Hana, Devor, Anna, Boas, David A., Sakadžić, Sava, Yaseen, Mohammad A.
Publicado 2018

Differential reductions in the capillary red-blood-cell flux between retina and brain under chronic global hypoperfusion

por Li, Baoqiang, Leng, Ji, Şencan-Eğilmez, Ikbal, Takase, Hajime, Alfadhel, Mohammed Ali H., Fu, Buyin, Shahidi, Mahnaz, Lo, Eng H., Arai, Ken, Sakadžić, Sava
Publicado 2023

Anatomical Modeling of Brain Vasculature in Two-Photon Microscopy by Generalizable Deep Learning

por Tahir, Waleed, Kura, Sreekanth, Zhu, Jiabei, Cheng, Xiaojun, Damseh, Rafat, Tadesse, Fetsum, Seibel, Alex, Lee, Blaire S., Lesage, Frédéric, Sakadžic, Sava, Boas, David A., Tian, Lei
Publicado 2020

Cortical microvascular blood flow velocity mapping by combining dynamic light scattering optical coherence tomography and two-photon microscopy

por Pian, Qi, Alfadhel, Mohammed, Tang, Jianbo, Lee, Grace V., Li, Baoqiang, Fu, Buyin, Ayata, Yagmur, Yaseen, Mohammad Abbas, Boas, David A., Secomb, Timothy W., Sakadzic, Sava
Publicado 2023

Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue

por Sakadžić, Sava, Roussakis, Emmanuel, Yaseen, Mohammad A., Mandeville, Emiri T., Srinivasan, Vivek J., Arai, Ken, Ruvinskaya, Svetlana, Devor, Anna, Lo, Eng H., Vinogradov, Sergei A., Boas, David A.
Publicado 2010

Multiparametric, Longitudinal Optical Coherence Tomography Imaging Reveals Acute Injury and Chronic Recovery in Experimental Ischemic Stroke

por Srinivasan, Vivek J., Mandeville, Emiri T., Can, Anil, Blasi, Francesco, Climov, Mihail, Daneshmand, Ali, Lee, Jeong Hyun, Yu, Esther, Radhakrishnan, Harsha, Lo, Eng H., Sakadžić, Sava, Eikermann-Haerter, Katharina, Ayata, Cenk
Publicado 2013

Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain

por Kisler, Kassandra, Nelson, Amy R., Rege, Sanket V., Ramanathan, Anita, Wang, Yaoming, Ahuja, Ashim, Lazic, Divna, Tsai, Philbert S., Zhao, Zhen, Zhou, Yi, Boas, David A., Sakadžić, Sava, Zlokovic, Berislav V.
Publicado 2017

More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction

por Li, Baoqiang, Esipova, Tatiana V, Sencan, Ikbal, Kılıç, Kıvılcım, Fu, Buyin, Desjardins, Michele, Moeini, Mohammad, Kura, Sreekanth, Yaseen, Mohammad A, Lesage, Frederic, Østergaard, Leif, Devor, Anna, Boas, David A, Vinogradov, Sergei A, Sakadžić, Sava
Publicado 2019

Large arteriolar component of oxygen delivery implies safe margin of oxygen supply to cerebral tissue

por Sakadžić, Sava, Mandeville, Emiri T., Gagnon, Louis, Musacchia, Joseph J., Yaseen, Mohammad A., Yucel, Meryem A, Lefebvre, Joel, Lesage, Frédéric, Dale, Anders M., Eikermann-Haerter, Katharina, Ayata, Cenk, Srinivasan, Vivek J., Lo, Eng H., Devor, Anna, Boas, David A.
Publicado 2014

Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation

por Shin, Paul, Pian, Qi, Ishikawa, Hidehiro, Hamanaka, Gen, Mandeville, Emiri T, Guo, Shuzhen, Fu, Buyin, Alfadhel, Mohammed, Allu, Srinivasa Rao, Şencan-Eğilmez, Ikbal, Li, Baoqiang, Ran, Chongzhao, Vinogradov, Sergei A, Ayata, Cenk, Lo, Eng, Arai, Ken, Devor, Anna, Sakadžić, Sava
Publicado 2023

CADASIL mutations sensitize the brain to ischemia via spreading depolarizations and abnormal extracellular potassium homeostasis

por Oka, Fumiaki, Lee, Jeong Hyun, Yuzawa, Izumi, Li, Mei, von Bornstaedt, Daniel, Eikermann-Haerter, Katharina, Qin, Tao, Chung, David Y., Sadeghian, Homa, Seidel, Jessica L., Imai, Takahiko, Vuralli, Doga, Platt, Rosangela M., Nelson, Mark T., Joutel, Anne, Sakadzic, Sava, Ayata, Cenk
Publicado 2022