A sustained-release drug-delivery system of synthetic prostacyclin agonist, ONO-1301SR: a new reagent to enhance cardiac tissue salvage and/or regeneration in the damaged heart

por Fukushima, Satsuki, Miyagawa, Shigeru, Sakai, Yoshiki, Sawa, Yoshiki
Publicado 2015

Histidine dephosphorylation of the Gβ protein GPB‐1 promotes axon regeneration in C. elegans

por Sakai, Yoshiki, Hanafusa, Hiroshi, Hisamoto, Naoki, Matsumoto, Kunihiro
Publicado 2022

N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans

por Shimizu, Tatsuhiro, Kato, Yuka, Sakai, Yoshiki, Hisamoto, Naoki, Matsumoto, Kunihiro
Publicado 2019

Synthetic Prostacyclin Agonist Attenuates Pressure-Overloaded Cardiac Fibrosis by Inhibiting FMT

por Masada, Kenta, Miyagawa, Shigeru, Sakai, Yoshiki, Harada, Akima, Kanaya, Tomomitsu, Sawa, Yoshiki
Publicado 2020

BRCA1–BARD1 Regulates Axon Regeneration in Concert with the Gqα–DAG Signaling Network

por Sakai, Yoshiki, Hanafusa, Hiroshi, Shimizu, Tatsuhiro, Pastuhov, Strahil I., Hisamoto, Naoki, Matsumoto, Kunihiro
Publicado 2021

Administration of Slow-Release Synthetic Prostacyclin Agonist Promoted Angiogenesis and Skeletal Muscle Regeneration for Limb Ischemia

por Nakagawa, Takaya, Miyagawa, Shigeru, Shibuya, Takashi, Sakai, Yoshiki, Harada, Akima, Watanabe, Kenichi, Sawa, Yoshiki
Publicado 2020

CDK14 Promotes Axon Regeneration by Regulating the Noncanonical Wnt Signaling Pathway in a Kinase-Independent Manner

por Hisamoto, Naoki, Sakai, Yoshiki, Ohta, Kohei, Shimizu, Tatsuhiro, Li, Chun, Hanafusa, Hiroshi, Matsumoto, Kunihiro
Publicado 2021

TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor

por Sakai, Yoshiki, Hanafusa, Hiroshi, Pastuhov, Strahil Iv, Shimizu, Tatsuhiro, Li, Chun, Hisamoto, Naoki, Matsumoto, Kunihiro
Publicado 2019

Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor

por Shimizu, Tatsuhiro, Pastuhov, Strahil I., Hanafusa, Hiroshi, Sakai, Yoshiki, Todoroki, Yasuko, Hisamoto, Naoki, Matsumoto, Kunihiro
Publicado 2021

Sustained-Release Delivery of Prostacyclin Analogue Enhances Bone Marrow-Cell Recruitment and Yields Functional Benefits for Acute Myocardial Infarction in Mice

por Imanishi, Yukiko, Miyagawa, Shigeru, Fukushima, Satsuki, Ishimaru, Kazuhiko, Sougawa, Nagako, Saito, Atsuhiro, Sakai, Yoshiki, Sawa, Yoshiki
Publicado 2013

Enhanced Pulmonary Vascular and Alveolar Development via Prenatal Administration of a Slow-Release Synthetic Prostacyclin Agonist in Rat Fetal Lung Hypoplasia

por Umeda, Satoshi, Miyagawa, Shigeru, Fukushima, Satsuki, Oda, Noriko, Saito, Atsuhiro, Sakai, Yoshiki, Sawa, Yoshiki, Okuyama, Hiroomi
Publicado 2016

The Integrin Signaling Network Promotes Axon Regeneration via the Src–Ephexin–RhoA GTPase Signaling Axis

por Sakai, Yoshiki, Tsunekawa, Mayuka, Ohta, Kohei, Shimizu, Tatsuhiro, Pastuhov, Strahil, Hanafusa, Hiroshi, Hisamoto, Naoki, Matsumoto, Kunihiro
Publicado 2021

Chemical Signaling Regulates Axon Regeneration via the GPCR–Gqα Pathway in Caenorhabditis elegans

por Shimizu, Tatsuhiro, Sugiura, Kayoko, Sakai, Yoshiki, Dar, Abdul R., Butcher, Rebecca A., Matsumoto, Kunihiro, Hisamoto, Naoki
Publicado 2022

Innovative therapeutic strategy using prostaglandin I(2) agonist (ONO1301) combined with nano drug delivery system for pulmonary arterial hypertension

por Kanaya, Tomomitsu, Miyagawa, Shigeru, Kawamura, Takuji, Sakai, Yoshiki, Masada, Kenta, Nawa, Nobutoshi, Ishida, Hidekazu, Narita, Jun, Toda, Koichi, Kuratani, Toru, Sawa, Yoshiki
Publicado 2021

Combined administration of laminin-221 and prostacyclin agonist enhances endogenous cardiac repair in an acute infarct rat heart

por Sougawa, Nagako, Miyagawa, Shigeru, Kawamura, Takuji, Matsuura, Ryohei, Harada, Akima, Sakai, Yoshiki, Mochizuki-Oda, Noriko, Sato-Nishiuchi, Ryoko, Sekiguchi, Kiyotoshi, Sawa, Yoshiki
Publicado 2021

Prostacyclin Analogue–Loaded Nanoparticles Attenuate Myocardial Ischemia/Reperfusion Injury in Rats

por Yajima, Shin, Miyagawa, Shigeru, Fukushima, Satsuki, Sakai, Yoshiki, Iseoka, Hiroko, Harada, Akima, Isohashi, Kayako, Horitsugi, Genki, Mori, Yuki, Shiozaki, Motoko, Ohkawara, Hirotatsu, Sakaniwa, Ryoto, Hatazawa, Jun, Yoshioka, Yoshichika, Sawa, Yoshiki
Publicado 2019

Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis

por Tada, Satoru, Okuno, Tatsusada, Shimizu, Mikito, Sakai, Yoshiki, Sumi-Akamaru, Hisae, Kinoshita, Makoto, Yamashita, Kazuya, Sanda, Eri, Choong, Chi-Jing, Namba, Akiko, Sasaki, Tsutomu, Koda, Toru, Takata, Kazushiro, Miyagawa, Shigeru, Sawa, Yoshiki, Nakatsuji, Yuji, Mochizuki, Hideki
Publicado 2019