KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution

por Otsuka, Kai, Sakashita, Akihiko, Maezawa, So, Schultz, Richard M., Namekawa, Satoshi H.
Publicado 2023

Suppression of endogenous retroviral enhancers in mouse embryos derived from somatic cell nuclear transfer

por Shikata, Daiki, Matoba, Shogo, Hada, Masashi, Sakashita, Akihiko, Inoue, Kimiko, Ogura, Atsuo
Publicado 2022

Transcription of MERVL retrotransposons is required for preimplantation embryo development

por Sakashita, Akihiko, Kitano, Tomohiro, Ishizu, Hirotsugu, Guo, Youjia, Masuda, Harumi, Ariura, Masaru, Murano, Kensaku, Siomi, Haruhiko
Publicado 2023

Sex Specification and Heterogeneity of Primordial Germ Cells in Mice

por Sakashita, Akihiko, Kawabata, Yukiko, Jincho, Yuko, Tajima, Shiun, Kumamoto, Soichiro, Kobayashi, Hisato, Matsui, Yasuhisa, Kono, Tomohiro
Publicado 2015

Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development

por Alavattam, Kris G., Maezawa, So, Sakashita, Akihiko, Khoury, Haia, Barski, Artem, Kaplan, Noam, Namekawa, Satoshi H.
Publicado 2019

Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin

por Sakashita, Akihiko, Ooga, Masatoshi, Otsuka, Kai, Maezawa, So, Takeuchi, Chikara, Wakayama, Sayaka, Wakayama, Teruhiko, Namekawa, Satoshi H
Publicado 2023

XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage()

por Sakashita, Akihiko, Wakai, Takuya, Kawabata, Yukiko, Nishimura, Chiaki, Sotomaru, Yusuke, Alavattam, Kris G, Namekawa, Satoshi H, Kono, Tomohiro
Publicado 2019

Epigenetic and transcriptional features of the novel human imprinted lncRNA GPR1AS suggest it is a functional ortholog to mouse Zdbf2linc

por Kobayashi, Hisato, Yanagisawa, Eikichi, Sakashita, Akihiko, Sugawara, Naoko, Kumakura, Shiori, Ogawa, Hidehiko, Akutsu, Hidenori, Hata, Kenichiro, Nakabayashi, Kazuhiko, Kono, Tomohiro
Publicado 2013

Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition

por Maezawa, So, Sakashita, Akihiko, Yukawa, Masashi, Chen, Xiaoting, Takahashi, Kazuki, Alavattam, Kris G., Nakata, Ippo, Weirauch, Matthew T., Barski, Artem, Namekawa, Satoshi H.
Publicado 2020

Polycomb directs timely activation of germline genes in spermatogenesis

por Maezawa, So, Hasegawa, Kazuteru, Yukawa, Masashi, Sakashita, Akihiko, Alavattam, Kris G., Andreassen, Paul R., Vidal, Miguel, Koseki, Haruhiko, Barski, Artem, Namekawa, Satoshi H.
Publicado 2017

High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

por Kobayashi, Hisato, Sakurai, Takayuki, Miura, Fumihito, Imai, Misaki, Mochiduki, Kentaro, Yanagisawa, Eikichi, Sakashita, Akihiko, Wakai, Takuya, Suzuki, Yutaka, Ito, Takashi, Matsui, Yasuhisa, Kono, Tomohiro
Publicado 2013

Amplification-free whole-genome shotgun bisulfite sequencing of mouse primordial germ cells

por Kobayashi, Hisato, Sakurai, Takayuki, Miura, Fumihito, Imai, Misaki, Mochiduki, Kentaro, Yanagisawa, Eikichi, Sakashita, Akihiko, Wakai, Takuya, Suzuki, Yutaka, lto, Takashi, Matsui, Yasuhisa, Kono, Tomohiro
Publicado 2013

PRC1-mediated epigenetic programming is required to generate the ovarian reserve

por Hu, Mengwen, Yeh, Yu-Han, Munakata, Yasuhisa, Abe, Hironori, Sakashita, Akihiko, Maezawa, So, Vidal, Miguel, Koseki, Haruhiko, Hunter, Neil, Schultz, Richard M., Namekawa, Satoshi H.
Publicado 2022

PRC1 suppresses a female gene regulatory network to ensure testicular differentiation

por Maezawa, So, Yukawa, Masashi, Hasegawa, Kazuteru, Sugiyama, Ryo, Iizuka, Mizuho, Hu, Mengwen, Sakashita, Akihiko, Vidal, Miguel, Koseki, Haruhiko, Barski, Artem, DeFalco, Tony, Namekawa, Satoshi H.
Publicado 2023

Endogenous retroviruses drive species-specific germline transcriptomes in mammals

por Sakashita, Akihiko, Maezawa, So, Takahashi, Kazuki, Alavattam, Kris G., Yukawa, Masashi, Hu, Yueh-Chiang, Kojima, Shohei, Parrish, Nicholas F., Barski, Artem, Pavlicev, Mihaela, Namekawa, Satoshi H.
Publicado 2020

LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation

por Brind’Amour, Julie, Kobayashi, Hisato, Richard Albert, Julien, Shirane, Kenjiro, Sakashita, Akihiko, Kamio, Asuka, Bogutz, Aaron, Koike, Tasuku, Karimi, Mohammad M., Lefebvre, Louis, Kono, Tomohiro, Lorincz, Matthew C.
Publicado 2018

The EZH2–PRC2–H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasion

por Fukui, Yamato, Hirota, Yasushi, Aikawa, Shizu, Sakashita, Akihiko, Shimizu-Hirota, Ryoko, Takeda, Norihiko, Ishizawa, Chihiro, Iida, Rei, Kaku, Tetsuaki, Hirata, Tomoyuki, Hiraoka, Takehiro, Akaeda, Shun, Matsuo, Mitsunori, Osuga, Yutaka
Publicado 2023

UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells

por Dong, Juan, Wang, Xiaoli, Cao, Congcong, Wen, Yujiao, Sakashita, Akihiko, Chen, Si, Zhang, Jin, Zhang, Yue, Zhou, Liquan, Luo, Mengcheng, Liu, Mingxi, Liao, Aihua, Namekawa, Satoshi H., Yuan, Shuiqiao
Publicado 2019

RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes

por Adams, Shannel R., Maezawa, So, Alavattam, Kris G., Abe, Hironori, Sakashita, Akihiko, Shroder, Megan, Broering, Tyler J., Sroga Rios, Julie, Thomas, Michael A., Lin, Xinhua, Price, Carolyn M., Barski, Artem, Andreassen, Paul R., Namekawa, Satoshi H.
Publicado 2018

Highly rigid H3.1/H3.2–H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells

por Hada, Masashi, Miura, Hisashi, Tanigawa, Akie, Matoba, Shogo, Inoue, Kimiko, Ogonuki, Narumi, Hirose, Michiko, Watanabe, Naomi, Nakato, Ryuichiro, Fujiki, Katsunori, Hasegawa, Ayumi, Sakashita, Akihiko, Okae, Hiroaki, Miura, Kento, Shikata, Daiki, Arima, Takahiro, Shirahige, Katsuhiko, Hiratani, Ichiro, Ogura, Atsuo
Publicado 2022