Induced Synthesis of O(6)‐Methylguanine‐DNA Methyltransferase in Rat Hepatoma Cells Exposed to DNA‐damaging Agents

por Fukuhara, Masao, Hayakawa, Hiroshi, Sakumi, Kunihiko, Sekiguchi, Mutsuo
Publicado 1992

8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

por Leon, Julio, Sakumi, Kunihiko, Castillo, Erika, Sheng, Zijing, Oka, Sugako, Nakabeppu, Yusaku
Publicado 2016

Corrigendum: 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative con...

por Leon, Julio, Sakumi, Kunihiko, Castillo, Erika, Sheng, Zijing, Oka, Sugako, Nakabeppu, Yusaku
Publicado 2016

A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA

por Ushijima, Yasuhiro, Tominaga, Yohei, Miura, Tomofumi, Tsuchimoto, Daisuke, Sakumi, Kunihiko, Nakabeppu, Yusaku
Publicado 2005

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

por Abolhassani, Nona, Iyama, Teruaki, Tsuchimoto, Daisuke, Sakumi, Kunihiko, Ohno, Mizuki, Behmanesh, Mehrdad, Nakabeppu, Yusaku
Publicado 2010

8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction

por Sampath, Harini, Vartanian, Vladimir, Rollins, M. Rick, Sakumi, Kunihiko, Nakabeppu, Yusaku, Lloyd, R. Stephen
Publicado 2012

Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer’s disease

por Oka, Sugako, Leon, Julio, Sakumi, Kunihiko, Ide, Tomomi, Kang, Dongchon, LaFerla, Frank M., Nakabeppu, Yusaku
Publicado 2016

A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App (NL−F/NL−F) knock‐in mouse model

por Mazzei, Guianfranco, Ikegami, Ryohei, Abolhassani, Nona, Haruyama, Naoki, Sakumi, Kunihiko, Saito, Takashi, Saido, Takaomi C., Nakabeppu, Yusaku
Publicado 2021

Neural stem cell–specific ITPA deficiency causes neural depolarization and epilepsy

por Koga, Yuichiro, Tsuchimoto, Daisuke, Hayashi, Yoshinori, Abolhassani, Nona, Yoneshima, Yasuto, Sakumi, Kunihiko, Nakanishi, Hiroshi, Toyokuni, Shinya, Nakabeppu, Yusaku
Publicado 2020

MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis

por Oka, Sugako, Leon, Julio, Sakumi, Kunihiko, Abolhassani, Nona, Sheng, Zijing, Tsuchimoto, Daisuke, LaFerla, Frank M., Nakabeppu, Yusaku
Publicado 2021

8-oxoguanine causes spontaneous de novo germline mutations in mice

por Ohno, Mizuki, Sakumi, Kunihiko, Fukumura, Ryutaro, Furuichi, Masato, Iwasaki, Yuki, Hokama, Masaaki, Ikemura, Toshimichi, Tsuzuki, Teruhisa, Gondo, Yoichi, Nakabeppu, Yusaku
Publicado 2014

Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells

por Yoneshima, Yasuto, Abolhassani, Nona, Iyama, Teruaki, Sakumi, Kunihiko, Shiomi, Naoko, Mori, Masahiko, Shiomi, Tadahiro, Noda, Tetsuo, Tsuchimoto, Daisuke, Nakabeppu, Yusaku
Publicado 2016

MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease

por Mizuno, Yuri, Abolhassani, Nona, Mazzei, Guianfranco, Sakumi, Kunihiko, Saito, Takashi, Saido, Takaomi C., Ninomiya, Toshiharu, Iwaki, Toru, Yamasaki, Ryo, Kira, Jun-ichi, Nakabeppu, Yusaku
Publicado 2021

Corrigendum to “MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease”

por Mizuno, Yuri, Abolhassani, Nona, Mazzei, Guianfranco, Sakumi, Kunihiko, Saito, Takashi, Saido, Takaomi C., Ninomiya, Toshiharu, Iwaki, Toru, Yamasaki, Ryo, Kira, Jun-ichi, Nakabeppu, Yusaku
Publicado 2023

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease

por Fujita, Kyota, Seike, Toshihiro, Yutsudo, Noriko, Ohno, Mizuki, Yamada, Hidetaka, Yamaguchi, Hiroo, Sakumi, Kunihiko, Yamakawa, Yukiko, Kido, Mizuho A., Takaki, Atsushi, Katafuchi, Toshihiko, Tanaka, Yoshinori, Nakabeppu, Yusaku, Noda, Mami
Publicado 2009

Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

por Castillo, Erika, Leon, Julio, Mazzei, Guianfranco, Abolhassani, Nona, Haruyama, Naoki, Saito, Takashi, Saido, Takaomi, Hokama, Masaaki, Iwaki, Toru, Ohara, Tomoyuki, Ninomiya, Toshiharu, Kiyohara, Yutaka, Sakumi, Kunihiko, LaFerla, Frank M., Nakabeppu, Yusaku
Publicado 2017

Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation...

por Castillo, Erika, Leon, Julio, Mazzei, Guianfranco, Abolhassani, Nona, Haruyama, Naoki, Saito, Takashi, Saido, Takaomi, Hokama, Masaaki, Iwaki, Toru, Ohara, Tomoyuki, Ninomiya, Toshiharu, Kiyohara, Yutaka, Sakumi, Kunihiko, LaFerla, Frank M., Nakabeppu, Yusaku
Publicado 2021