Orai1–STIM1 Regulates Increased Ca(2+) Mobilization, Leading to Contractile Duchenne Muscular Dystrophy Phenotypes in Patient-Derived Induced Pluripotent Stem Cells

por Uchimura, Tomoya, Sakurai, Hidetoshi
Publicado 2021

Uniform transgene activation in Tet-On systems depends on sustained rtTA expression

por Otomo, Jun, Woltjen, Knut, Sakurai, Hidetoshi
Publicado 2023

A new immunodeficient Duchenne muscular dystrophy rat model to evaluate engraftment after human cell transplantation

por Sato, Masae, Goto, Megumi, Yamanouchi, Keitaro, Sakurai, Hidetoshi
Publicado 2023

Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9

por Higashioka, Koki, Koizumi, Noriko, Sakurai, Hidetoshi, Sotozono, Chie, Sato, Takahiko
Publicado 2017

A Liver Model of Infantile-Onset Pompe Disease Using Patient-Specific Induced Pluripotent Stem Cells

por Yoshida, Takeshi, Jonouchi, Tatsuya, Osafune, Kenji, Takita, Junko, Sakurai, Hidetoshi
Publicado 2019

A muscle fatigue-like contractile decline was recapitulated using skeletal myotubes from Duchenne muscular dystrophy patient-derived iPSCs

por Uchimura, Tomoya, Asano, Toshifumi, Nakata, Takao, Hotta, Akitsu, Sakurai, Hidetoshi
Publicado 2021

Functional validation and expression analysis of myotubes converted from skin fibroblasts using a simple direct reprogramming strategy

por Horio, Fukuko, Sakurai, Hidetoshi, Ohsawa, Yutaka, Nakano, Shiho, Matsukura, Makoto, Fujii, Isao
Publicado 2016

Identification of Novel Antisense-Mediated Exon Skipping Targets in DYSF for Therapeutic Treatment of Dysferlinopathy

por Lee, Joshua J.A., Maruyama, Rika, Duddy, William, Sakurai, Hidetoshi, Yokota, Toshifumi
Publicado 2018

Transplantation of human iPSC-derived muscle stem cells in the diaphragm of Duchenne muscular dystrophy model mice

por Miura, Yasutomo, Sato, Mase, Kuwahara, Toshie, Ebata, Tomoki, Tabata, Yasuhiko, Sakurai, Hidetoshi
Publicado 2022

Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs

por Kawada, Ryu, Jonouchi, Tatsuya, Kagita, Akihiro, Sato, Masae, Hotta, Akitsu, Sakurai, Hidetoshi
Publicado 2023

Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In Vitro

por Ishii, Kana, Sakurai, Hidetoshi, Suzuki, Nobuharu, Mabuchi, Yo, Sekiya, Ichiro, Sekiguchi, Kiyotoshi, Akazawa, Chihiro
Publicado 2018

Human Skeletal Muscle Cells Derived from the Orbicularis Oculi Have Regenerative Capacity for Duchenne Muscular Dystrophy

por Yamanaka, Yukito, Takenaka, Nana, Sakurai, Hidetoshi, Ueno, Morio, Kinoshita, Shigeru, Sotozono, Chie, Sato, Takahiko
Publicado 2019

Core Transcription Factors Promote Induction of PAX3-Positive Skeletal Muscle Stem Cells

por Sato, Takahiko, Higashioka, Koki, Sakurai, Hidetoshi, Yamamoto, Takuya, Goshima, Naoki, Ueno, Morio, Sotozono, Chie
Publicado 2019

Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells

por Mitsuhashi, Satomi, Nakagawa, So, Sasaki-Honda, Mitsuru, Sakurai, Hidetoshi, Frith, Martin C, Mitsuhashi, Hiroaki
Publicado 2021

Fetal Skeletal Muscle Progenitors Have Regenerative Capacity after Intramuscular Engraftment in Dystrophin Deficient Mice

por Sakai, Hiroshi, Sato, Takahiko, Sakurai, Hidetoshi, Yamamoto, Takuya, Hanaoka, Kazunori, Montarras, Didier, Sehara-Fujisawa, Atsuko
Publicado 2013

Single-cell RNA-seq reveals heterogeneity in hiPSC-derived muscle progenitors and E2F family as a key regulator of proliferation

por Nalbandian, Minas, Zhao, Mingming, Kato, Hiroki, Jonouchi, Tatsuya, Nakajima-Koyama, May, Yamamoto, Takuya, Sakurai, Hidetoshi
Publicado 2022

Mature Myotubes Generated From Human-Induced Pluripotent Stem Cells Without Forced Gene Expression

por Fujiwara, Kei, Yamamoto, Risa, Kubota, Tomoya, Tazumi, Atsutoshi, Sabuta, Tomoka, Takahashi, Masanori P., Sakurai, Hidetoshi
Publicado 2022

A Skeletal Muscle Model of Infantile-onset Pompe Disease with Patient-specific iPS Cells

por Yoshida, Takeshi, Awaya, Tomonari, Jonouchi, Tatsuya, Kimura, Ryo, Kimura, Shigemi, Era, Takumi, Heike, Toshio, Sakurai, Hidetoshi
Publicado 2017

Modeling human somite development and fibrodysplasia ossificans progressiva with induced pluripotent stem cells

por Nakajima, Taiki, Shibata, Mitsuaki, Nishio, Megumi, Nagata, Sanae, Alev, Cantas, Sakurai, Hidetoshi, Toguchida, Junya, Ikeya, Makoto
Publicado 2018

RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs

por Komatsu, Yumiko, Takeuchi, Dan, Tokunaga, Tomoya, Sakurai, Hidetoshi, Makino, Akiko, Honda, Tomoyuki, Ikeda, Yasuhiro, Tomonaga, Keizo
Publicado 2019