Force and Calcium Transients Analysis in Human Engineered Heart Tissues Reveals Positive Force-Frequency Relation at Physiological Frequency

por Saleem, Umber, Mannhardt, Ingra, Braren, Ingke, Denning, Chris, Eschenhagen, Thomas, Hansen, Arne
Publicado 2020

Regulation of I(Ca,L) and force by PDEs in human‐induced pluripotent stem cell‐derived cardiomyocytes

por Saleem, Umber, Ismaili, Djemail, Mannhardt, Ingra, Pinnschmidt, Hans, Schulze, Thomas, Christ, Torsten, Eschenhagen, Thomas, Hansen, Arne
Publicado 2020

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I(bk,Ca))

por Horváth, András, Christ, Torsten, Koivumäki, Jussi T., Prondzynski, Maksymilian, Zech, Antonia T. L., Spohn, Michael, Saleem, Umber, Mannhardt, Ingra, Ulmer, Bärbel, Girdauskas, Evaldas, Meyer, Christian, Hansen, Arne, Eschenhagen, Thomas, Lemoine, Marc D.
Publicado 2020

A biallelic loss-of-function variant in MYZAP is associated with a recessive form of severe dilated cardiomyopathy

por Maver, Aleš, Žigman, Tamara, Rangrez, Ashraf Yusuf, Ćorić, Marijana, Homolak, Jan, Šarić, Dalibor, Škifić, Iva, Udovičić, Mario, Zekušić, Marija, Saleem, Umber, Laufer, Sandra D., Hansen, Arne, Frey, Norbert, Barić, Ivo, Peterlin, Borut
Publicado 2022

Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format

por Mannhardt, Ingra, Saleem, Umber, Mosqueira, Diogo, Loos, Malte F., Ulmer, Bärbel M., Lemoine, Marc D., Larsson, Camilla, Améen, Caroline, de Korte, Tessa, Vlaming, Maria L.H., Harris, Kate, Clements, Peter, Denning, Chris, Hansen, Arne, Eschenhagen, Thomas
Publicado 2020

Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes

por Saleem, Umber, van Meer, Berend J, Katili, Puspita A, Mohd Yusof, Nurul A N, Mannhardt, Ingra, Garcia, Ana Krotenberg, Tertoolen, Leon, de Korte, Tessa, Vlaming, Maria L H, McGlynn, Karen, Nebel, Jessica, Bahinski, Anthony, Harris, Kate, Rossman, Eric, Xu, Xiaoping, Burton, Francis L, Smith, Godfrey L, Clements, Peter, Mummery, Christine L, Eschenhagen, Thomas, Hansen, Arne, Denning, Chris
Publicado 2020

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

por Cuello, Friederike, Knaust, Anika E, Saleem, Umber, Loos, Malte, Raabe, Janice, Mosqueira, Diogo, Laufer, Sandra, Schweizer, Michaela, van der Kraak, Petra, Flenner, Frederik, Ulmer, Bärbel M, Braren, Ingke, Yin, Xiaoke, Theofilatos, Konstantinos, Ruiz‐Orera, Jorge, Patone, Giannino, Klampe, Birgit, Schulze, Thomas, Piasecki, Angelika, Pinto, Yigal, Vink, Aryan, Hübner, Norbert, Harding, Sian, Mayr, Manuel, Denning, Chris, Eschenhagen, Thomas, Hansen, Arne
Publicado 2021

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo

por Sala, Luca, van Meer, Berend J., Tertoolen, Leon G.J., Bakkers, Jeroen, Bellin, Milena, Davis, Richard P., Denning, Chris, Dieben, Michel A.E., Eschenhagen, Thomas, Giacomelli, Elisa, Grandela, Catarina, Hansen, Arne, Holman, Eduard R., Jongbloed, Monique R.M., Kamel, Sarah M., Koopman, Charlotte D., Lachaud, Quentin, Mannhardt, Ingra, Mol, Mervyn P.H., Mosqueira, Diogo, Orlova, Valeria V., Passier, Robert, Ribeiro, Marcelo C., Saleem, Umber, Smith, Godfrey L., Burton, Francis L., Mummery, Christine L.
Publicado 2018