Pre-clinical delivery of gene therapy products to the cerebrospinal fluid: challenges and considerations for clinical translation

por Salegio, Ernesto A., Hancock, Kelli, Korszen, Stephanie
Publicado 2023

Macrophage presence is essential for the regeneration of ascending afferent fibres following a conditioning sciatic nerve lesion in adult rats

por Aguilar Salegio, Ernesto A, Pollard, Anthony N, Smith, Malcolm, Zhou, Xin-Fu
Publicado 2011

Automated Segmentation Tool for Brain Infusions

por Rosenbluth, Kathryn Hammond, Gimenez, Francisco, Kells, Adrian P., Salegio, Ernesto A., Mittermeyer, Gabriele M., Modera, Kevin, Kohal, Anmol, Bankiewicz, Krystof S.
Publicado 2013

Axonal transport of adeno-associated viral vectors is serotype-dependent

por Salegio, Ernesto A., Samaranch, Lluis, Kells, Adrian P., Mittermeyer, Gabriele, San Sebastian, Waldy, Zhou, Shangzhen, Beyer, Janine, Forsayeth, John, Bankiewicz, Krystof S.
Publicado 2012

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy

por Salegio, Ernesto A., Streeter, Hillary, Dube, Nikhil, Hadaczek, Piotr, Samaranch, Lluis, Kells, Adrian P., San Sebastian, Waldy, Zhai, Yuying, Bringas, John, Xu, Ting, Forsayeth, John, Bankiewicz, Krystof S.
Publicado 2014

Regulation of axon regeneration by the RNA repair/splicing pathway

por Song, Yuanquan, Sretavan, David, Salegio, Ernesto A, Berg, Jim, Huang, Xi, Cheng, Tong, Xiong, Xin, Meltzer, Shan, Han, Chun, Nguyen, Trong-Tuong, Bresnahan, Jacqueline C., Beattie, Michael S., Jan, Lily Yeh, Jan, Yuh Nung
Publicado 2015

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates

por Ohno, Kousaku, Samaranch, Lluis, Hadaczek, Piotr, Bringas, John R., Allen, Philip C., Sudhakar, Vivek, Stockinger, Diane E., Snieckus, Christopher, Campagna, Michael V., San Sebastian, Waldy, Naidoo, Jerusha, Chen, Haifeng, Forsayeth, John, Salegio, Ernesto A., Hwa, Granger G.C., Bankiewicz, Krystof S.
Publicado 2018

A Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates (Macaca mulatta)

por Salegio, Ernesto A., Bresnahan, Jacqueline C., Sparrey, Carolyn J., Camisa, William, Fischer, Jason, Leasure, Jeremi, Buckley, Jennifer, Nout-Lomas, Yvette S., Rosenzweig, Ephron S., Moseanko, Rod, Strand, Sarah, Hawbecker, Stephanie, Lemoy, Marie-Josee, Haefeli, Jenny, Ma, Xiaokui, Nielson, Jessica L., Edgerton, V.R., Ferguson, Adam R., Tuszynski, Mark H., Beattie, Michael S.
Publicado 2016

A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury

por Delbary-Gossart, Sandrine, Lee, Sangmi, Baroni, Marco, Lamarche, Isabelle, Arnone, Michele, Canolle, Benoit, Lin, Amity, Sacramento, Jeffrey, Salegio, Ernesto A., Castel, Marie-Noelle, Delesque-Touchard, Nathalie, Alam, Antoine, Laboudie, Patricia, Ferzaz, Badia, Savi, Pierre, Herbert, Jean-Marc, Manley, Geoffrey T., Ferguson, Adam R., Bresnahan, Jacqueline C., Bono, Françoise, Beattie, Michael S.
Publicado 2016

Chondroitinase Improves Anatomical and Functional Outcomes After Primate Spinal Cord Injury

por Rosenzweig, Ephron S., Salegio, Ernesto A., Liang, Justine J., Weber, Janet L., Weinholtz, Chase A., Brock, John H., Moseanko, Rod, Hawbecker, Stephanie, Pender, Roger, Cruzen, Christina L., Iaci, Jennifer F., Caggiano, Anthony O., Blight, Andrew R., Haenzi, Barbara, Huie, J. Russell, Havton, Leif A., Nout-Lomas, Yvette S., Fawcett, James W., Ferguson, Adam R., Beattie, Michael S., Bresnahan, Jacqueline C., Tuszynski, Mark H.
Publicado 2019