The Structural Binding Mode of the Four Autotaxin Inhibitor Types that Differentially Affect Catalytic and Non-Catalytic Functions

por Salgado-Polo, Fernando, Perrakis, Anastassis
Publicado 2019

Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity

por Borza, Razvan, Salgado-Polo, Fernando, Moolenaar, Wouter H., Perrakis, Anastassis
Publicado 2021

A type IV Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis

por Booijink, Richell, Salgado‐Polo, Fernando, Jamieson, Craig, Perrakis, Anastassis, Bansal, Ruchi
Publicado 2022

Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators

por Clark, Jennifer M., Salgado-Polo, Fernando, Macdonald, Simon J. F., Barrett, Tim N., Perrakis, Anastassis, Jamieson, Craig
Publicado 2022

LAHMA: structure analysis through local annotation of homology-matched amino acids

por van Beusekom, Bart, Damaskos, George, Hekkelman, Maarten L., Salgado-Polo, Fernando, Hiruma, Yoshitaka, Perrakis, Anastassis, Joosten, Robbie P.
Publicado 2021

Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation

por Salgado-Polo, Fernando, van Veen, Michiel, van den Broek, Bram, Jalink, Kees, Leyton-Puig, Daniela, Perrakis, Anastassis, Moolenaar, Wouter H., Matas-Rico, Elisa
Publicado 2020

Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8(+) T cells

por Matas-Rico, Elisa, Frijlink, Elselien, van der Haar Àvila, Irene, Menegakis, Apostolos, van Zon, Maaike, Morris, Andrew J., Koster, Jan, Salgado-Polo, Fernando, de Kivit, Sander, Lança, Telma, Mazzocca, Antonio, Johnson, Zoë, Haanen, John, Schumacher, Ton N., Perrakis, Anastassis, Verbrugge, Inge, van den Berg, Joost H., Borst, Jannie, Moolenaar, Wouter H.
Publicado 2021