Next‐Generation Genotoxicology: Using Modern Sequencing Technologies to Assess Somatic Mutagenesis and Cancer Risk

por Salk, Jesse J., Kennedy, Scott R.
Publicado 2019

Response to: ‘when man got his mtDNA deletions?’

por Taylor, Sean D, Salk, Jesse J, Bielas, Jason H
Publicado 2014

Exploring the implications of distinct mutational signatures and mutation rates in aging and cancer

por Fox, Edward J., Salk, Jesse J., Loeb, Lawrence A.
Publicado 2016

Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage

por Kennedy, Scott R., Salk, Jesse J., Schmitt, Michael W., Loeb, Lawrence A.
Publicado 2013

svCapture: efficient and specific detection of very low frequency structural variant junctions by error-minimized capture sequencing

por Wilson, Thomas E, Ahmed, Samreen, Higgins, Jake, Salk, Jesse J, Glover, Thomas W
Publicado 2023

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer

por Ericson, Nolan G., Kulawiec, Mariola, Vermulst, Marc, Sheahan, Kieran, O'Sullivan, Jacintha, Salk, Jesse J., Bielas, Jason H.
Publicado 2012

Two-temperature LATE-PCR endpoint genotyping

por Sanchez, J Aquiles, Abramowitz, Jessica D, Salk, Jesse J, Reis, Arthur H, Rice, John E, Pierce, Kenneth E, Wangh, Lawrence J
Publicado 2006

Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing

por Valentine, Charles C., Young, Robert R., Fielden, Mark R., Kulkarni, Rohan, Williams, Lindsey N., Li, Tan, Minocherhomji, Sheroy, Salk, Jesse J.
Publicado 2020

Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations

por LeBlanc, Danielle P. M., Meier, Matthew, Lo, Fang Yin, Schmidt, Elizabeth, Valentine, Charles, Williams, Andrew, Salk, Jesse J., Yauk, Carole L., Marchetti, Francesco
Publicado 2022

Extensive subclonal mutational diversity in human colorectal cancer and its significance

por Loeb, Lawrence A., Kohrn, Brendan F., Loubet-Senear, Kaitlyn J., Dunn, Yasmin J., Ahn, Eun Hyun, O’Sullivan, Jacintha N., Salk, Jesse J., Bronner, Mary P., Beckman, Robert A.
Publicado 2019

Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS)

por Nachmanson, Daniela, Lian, Shenyi, Schmidt, Elizabeth K., Hipp, Michael J., Baker, Kathryn T., Zhang, Yuezheng, Tretiakova, Maria, Loubet-Senear, Kaitlyn, Kohrn, Brendan F., Salk, Jesse J., Kennedy, Scott R., Risques, Rosa Ana
Publicado 2018

Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride

por Dodge, Annette E., LeBlanc, Danielle P. M., Zhou, Gu, Williams, Andrew, Meier, Matthew J., Van, Phu, Lo, Fang Yin, Valentine III, Charles C., Salk, Jesse J., Yauk, Carole L., Marchetti, Francesco
Publicado 2023

Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing

por Wang, Yiying, Mittelstaedt, Roberta A., Wynne, Rebecca, Chen, Ying, Cao, Xuefei, Muskhelishvili, Levan, Davis, Kelly, Robison, Timothy W., Sun, Wei, Schmidt, Elizabeth K., Smith, Thomas H., Norgaard, Zachary K., Valentine, Charles C., Yaplee, Jeffry, Williams, Lindsey N., Salk, Jesse J., Heflich, Robert H.
Publicado 2021

Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph+ ALL

por Short, Nicholas J., Kantarjian, Hagop, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Ravandi, Farhad, Cortes, Jorge, Konopleva, Marina, Issa, Ghayas C., Kornblau, Steven M., Garcia-Manero, Guillermo, Garris, Rebecca, Higgins, Jake, Pratt, Gabriel, Williams, Lindsey N., Valentine, Charles C., Rivera, Victor M., Pritchard, Justin, Salk, Jesse J., Radich, Jerald, Jabbour, Elias
Publicado 2020