Mathematical Model of Metabolism and Electrophysiology of Amino Acid and Glucose Stimulated Insulin Secretion: In Vitro Validation Using a β-Cell Line

por Salvucci, Manuela, Neufeld, Zoltan, Newsholme, Philip
Publicado 2013

The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer

por Fullstone, Gavin, Bauer, Tabea L., Guttà, Cristiano, Salvucci, Manuela, Prehn, Jochen H. M., Rehm, Markus
Publicado 2020

Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)

por Salvucci, Manuela, Crawford, Nyree, Stott, Katie, Bullman, Susan, Longley, Daniel B, Prehn, Jochen H M
Publicado 2022

Effect of TP53 deficiency and KRAS signaling on the bioenergetics of colon cancer cells in response to different substrates: A single cell study

por Kealey, James, Düssmann, Heiko, Llorente-Folch, Irene, Niewidok, Natalia, Salvucci, Manuela, Prehn, Jochen H. M., D’Orsi, Beatrice
Publicado 2022

System-based approaches as prognostic tools for glioblastoma

por Salvucci, Manuela, Zakaria, Zaitun, Carberry, Steven, Tivnan, Amanda, Seifert, Volker, Kögel, Donat, Murphy, Brona M., Prehn, Jochen H. M.
Publicado 2019

TRAIL signaling promotes entosis in colorectal cancer

por Bozkurt, Emir, Düssmann, Heiko, Salvucci, Manuela, Cavanagh, Brenton L., Van Schaeybroeck, Sandra, Longley, Daniel B., Martin, Seamus J., Prehn, Jochen H.M.
Publicado 2021

A Context-Dependent Role for MiR-124-3p on Cell Phenotype, Viability and Chemosensitivity in Neuroblastoma in vitro

por Nolan, John C., Salvucci, Manuela, Carberry, Steven, Barat, Ana, Segura, Miguel F., Fenn, Justine, Prehn, Jochen H. M., Stallings, Raymond L., Piskareva, Olga
Publicado 2020

The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer

por Carberry, Steven, D’Orsi, Beatrice, Monsefi, Naser, Salvucci, Manuela, Bacon, Orna, Fay, Joanna, Rehm, Markus, McNamara, Deborah, Kay, Elaine W., Prehn, Jochen H. M.
Publicado 2018

Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant

por Fichtner, Michael, Bozkurt, Emir, Salvucci, Manuela, McCann, Christopher, McAllister, Katherine A., Halang, Luise, Düssmann, Heiko, Kinsella, Sinéad, Crawford, Nyree, Sessler, Tamas, Longley, Daniel B., Prehn, Jochen H. M.
Publicado 2020

FLINO: a new method for immunofluorescence bioimage normalization

por Graf, John, Cho, Sanghee, McDonough, Elizabeth, Corwin, Alex, Sood, Anup, Lindner, Andreas, Salvucci, Manuela, Stachtea, Xanthi, Van Schaeybroeck, Sandra, Dunne, Philip D, Laurent-Puig, Pierre, Longley, Daniel, Prehn, Jochen H M, Ginty, Fiona
Publicado 2021

Apoptotic and Necroptotic Mediators are Differentially Expressed in Mucinous and Non-Mucinous Colorectal Cancer

por O’Connell, Emer, Reynolds, Ian S., Lindner, Andreas U., Salvucci, Manuela, O’Grady, Tony, Bacon, Orna, Cho, Sanghee, McDonough, Elizabeth, Longley, Daniel, Ginty, Fiona, McNamara, Deborah A., Burke, John P., Prehn, Jochen H. M.
Publicado 2022

Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome

por Duggan, William P., Salvucci, Manuela, Kisakol, Batuhan, Lindner, Andreas U., Reynolds, Ian S., Dussmann, Heiko, Fay, Joanna, O’Grady, Tony, Longley, Daniel B., Ginty, Fiona, Mc Donough, Elizabeth, Slade, Daniel J., Burke, John P., Prehn, Jochen H. M.
Publicado 2023

Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations

por Stachtea, Xanthi, Loughrey, Maurice B., Salvucci, Manuela, Lindner, Andreas U., Cho, Sanghee, McDonough, Elizabeth, Sood, Anup, Graf, John, Santamaria-Pang, Alberto, Corwin, Alex, Laurent-Puig, Pierre, Dasgupta, Sonali, Shia, Jinru, Owens, Jonathan R., Abate, Samantha, Van Schaeybroeck, Sandra, Lawler, Mark, Prehn, Jochen H. M., Ginty, Fiona, Longley, Daniel B.
Publicado 2021

Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells

por Fabro, Federica, Kers, Trisha V., Feller, Kate J., Beerens, Cecile, Ntafoulis, Ioannis, Idbaih, Ahmed, Verreault, Maite, Connor, Kate, Biswas, Archita, Salvucci, Manuela, Prehn, Jochen H. M., Byrne, Annette T., O’Farrell, Alice C., Lambrechts, Diether, Dilcan, Gonca, Lodi, Francesca, Arijs, Ingrid, Kremer, Andreas, Tching Chi Yen, Romain, Chien, Miao-Ping, Lamfers, Martine L. M., Leenstra, Sieger
Publicado 2023

Genomic and Transcriptomic Characterisation of Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

por Toomey, Sinead, Gunther, Jillian, Carr, Aoife, Weksberg, David C., Thomas, Valentina, Salvucci, Manuela, Bacon, Orna, Sherif, El-Masry, Fay, Joanna, Kay, Elaine W., Sheehan, Katherine M., McNamara, Deborah A., Sanders, Keith L, Mathew, Geena, Breathnach, Oscar S., Grogan, Liam, Morris, Patrick G., Foo, Wai C., You, Yi-Qian N., Prehn, Jochen H., O’Neill, Brian, Krishnan, Sunil, Hennessy, Bryan T., Furney, Simon J.
Publicado 2020

An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution

por Lindner, Andreas Ulrich, Salvucci, Manuela, McDonough, Elizabeth, Cho, Sanghee, Stachtea, Xanthi, O’Connell, Emer P., Corwin, Alex D., Santamaria-Pang, Alberto, Carberry, Steven, Fichtner, Michael, Van Schaeybroeck, Sandra, Laurent-Puig, Pierre, Burke, John P., McNamara, Deborah A., Lawler, Mark, Sood, Anup, Graf, John F., Rehm, Markus, Dunne, Philip D., Longley, Daniel B., Ginty, Fiona, Prehn, Jochen H. M.
Publicado 2021

Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers

por Ntafoulis, Ioannis, Kleijn, Anne, Ju, Jie, Jimenez-Cowell, Kevin, Fabro, Federica, Klein, Michelle, Chi Yen, Romain Tching, Balvers, Rutger K., Li, Yunlei, Stubbs, Andrew P., Kers, Trisha V., Kros, Johan M., Lawler, Sean E., Beerepoot, Laurens V., Kremer, Andreas, Idbaih, Ahmed, Verreault, Maite, Byrne, Annette T., O’Farrell, Alice C., Connor, Kate, Biswas, Archita, Salvucci, Manuela, Prehn, Jochen H. M., Lambrechts, Diether, Dilcan, Gonca, Lodi, Francesca, Arijs, Ingrid, van den Bent, Martin J., Dirven, Clemens M. F., Leenstra, Sieger, Lamfers, Martine L. M.
Publicado 2023

Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

por Biswas, Archita, Salvucci, Manuela, Connor, Kate, Düssmann, Heiko, Carberry, Steven, Fichtner, Michael, King, Ellen, Murphy, Brona, O’Farrell, Alice C., Cryan, Jane, Beausang, Alan, Heffernan, Josephine, Cremona, Mattia, Hennessy, Bryan T., Clerkin, James, Sweeney, Kieron J., MacNally, Steve, Brett, Francesca, O’Halloran, Philip, Bacon, Orna, Furney, Simon, Verreault, Maite, Quissac, Emie, Bielle, Franck, Ahmed, Mohammed H., Idbaih, Ahmed, Leenstra, Sieger, Ntafoulis, Ioannis, Fabro, Federica, Lamfers, Martine, Golebiewska, Anna, Hertel, Frank, Niclou, Simone P., Yen, Romain Tching Chi, Kremer, Andreas, Dilcan, Gonca, Lodi, Francesca, Arijs, Ingrid, Lambrechts, Diether, Purushothama, Manasa Kalya, Kel, Alexander, Byrne, Annette T., Prehn, Jochen H.M.
Publicado 2023

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

por Connolly, Niamh M. C., Theurey, Pierre, Adam-Vizi, Vera, Bazan, Nicolas G., Bernardi, Paolo, Bolaños, Juan P., Culmsee, Carsten, Dawson, Valina L., Deshmukh, Mohanish, Duchen, Michael R., Düssmann, Heiko, Fiskum, Gary, Galindo, Maria F., Hardingham, Giles E., Hardwick, J. Marie, Jekabsons, Mika B., Jonas, Elizabeth A., Jordán, Joaquin, Lipton, Stuart A., Manfredi, Giovanni, Mattson, Mark P., McLaughlin, BethAnn, Methner, Axel, Murphy, Anne N., Murphy, Michael P., Nicholls, David G., Polster, Brian M., Pozzan, Tullio, Rizzuto, Rosario, Satrústegui, Jorgina, Slack, Ruth S., Swanson, Raymond A., Swerdlow, Russell H., Will, Yvonne, Ying, Zheng, Joselin, Alvin, Gioran, Anna, Moreira Pinho, Catarina, Watters, Orla, Salvucci, Manuela, Llorente-Folch, Irene, Park, David S., Bano, Daniele, Ankarcrona, Maria, Pizzo, Paola, Prehn, Jochen H. M.
Publicado 2017