Is Glucagon Receptor Activation the Thermogenic Solution for Treating Obesity?

por Conceição-Furber, Ellen, Coskun, Tamer, Sloop, Kyle W., Samms, Ricardo J.
Publicado 2022

GIPR Function in the Central Nervous System: Implications and Novel Perspectives for GIP-Basedz Therapies in Treating Metabolic Disorders

por Samms, Ricardo J., Sloop, Kyle W., Gribble, Fiona M., Reimann, Frank, Adriaenssens, Alice E.
Publicado 2021

Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster

por Lewis, Jo E., Samms, Ricardo J., Cooper, Scott, Luckett, Jeni C., Perkins, Alan C., Adams, Andrew C., Tsintzas, Kostas, Ebling, Francis J. P.
Publicado 2017

GIP receptor agonism blocks chemotherapy-induced nausea and vomiting

por Borner, Tito, Reiner, Benjamin C., Crist, Richard C., Furst, C. Daniel, Doebley, Sarah A., Halas, Julia G., Ai, Minrong, Samms, Ricardo J., De Jonghe, Bart C., Hayes, Matthew R.
Publicado 2023

The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis

por Antonellis, Patrick J., Droz, Brian A., Cosgrove, Richard, O'Farrell, Libbey S., Coskun, Tamer, Perfield, James W., Bauer, Steven, Wade, Mark, Chouinard, Tara E., Brozinick, Joseph T., Adams, Andrew C., Samms, Ricardo J.
Publicado 2019

Serum FGF21 levels are associated with brown adipose tissue activity in humans

por Hanssen, Mark J.W., Broeders, Evie, Samms, Ricardo J., Vosselman, Maarten J., van der Lans, Anouk A.J.J., Cheng, Christine C., Adams, Andrew C., van Marken Lichtenbelt, Wouter D., Schrauwen, Patrick
Publicado 2015

Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice

por Lewis, Jo E., Samms, Ricardo J., Cooper, Scott, Luckett, Jeni C., Perkins, Alan C., Dunbar, James D., Smith, Dennis P., Emmerson, Paul J., Adams, Andrew C., Ebling, Francis J. P., Tsintzas, Kostas
Publicado 2017

Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster

por Lewis, Jo E., Monnier, Chloe, Marshall, Hayley, Fowler, Maxine, Green, Rebecca, Cooper, Scott, Chiotellis, Aristeidis, Luckett, Jeni, Perkins, Alan C., Coskun, Tamer, Adams, Andrew C., Samms, Ricardo J., Ebling, Francis J.P., Tsintzas, Kostas
Publicado 2019

Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue

por Samms, Ricardo J., Zhang, GuoFang, He, Wentao, Ilkayeva, Olga, Droz, Brian A., Bauer, Steven M., Stutsman, Cynthia, Pirro, Valentina, Collins, Kyla A., Furber, Ellen C., Coskun, Tamer, Sloop, Kyle W., Brozinick, Joseph T., Newgard, Christopher B.
Publicado 2022

GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior

por Samms, Ricardo J., Cosgrove, Richard, Snider, Brandy M., Furber, Ellen C., Droz, Brian A., Briere, Daniel A., Dunbar, James, Dogra, Mridula, Alsina-Fernandez, Jorge, Borner, Tito, De Jonghe, Bart C., Hayes, Matthew R., Coskun, Tamer, Sloop, Kyle W., Emmerson, Paul J., Ai, Minrong
Publicado 2022

Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding

por Adriaenssens, Alice, Broichhagen, Johannes, de Bray, Anne, Ast, Julia, Hasib, Annie, Jones, Ben, Tomas, Alejandra, Burgos, Natalie Figueredo, Woodward, Orla, Lewis, Jo, O’Flaherty, Elisabeth, El, Kimberley, Cui, Canqi, Harada, Norio, Inagaki, Nobuya, Campbell, Jonathan, Brierley, Daniel, Hodson, David J., Samms, Ricardo, Gribble, Fiona, Reimann, Frank
Publicado 2023

GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist–Induced Nausea and Emesis in Preclinical Models

por Borner, Tito, Geisler, Caroline E., Fortin, Samantha M., Cosgrove, Richard, Alsina-Fernandez, Jorge, Dogra, Mridula, Doebley, Sarah, Sanchez-Navarro, Marcos J., Leon, Rosa M., Gaisinsky, Jane, White, Arianna, Bamezai, Ankur, Ghidewon, Misgana Y., Grill, Harvey J., Crist, Richard C., Reiner, Benjamin C., Ai, Minrong, Samms, Ricardo J., De Jonghe, Bart C., Hayes, Matthew R.
Publicado 2021