Case Report: Management of an Elderly Patient With Metastatic Radioiodine-Resistant Differentiated Thyroid Cancer in a Rural Community, Remote From Specialist Oncology Services

por Wybrew, Rachael, Loynd, Michael, Wybrew, Maria, Samuel, Leslie
Publicado 2021

Young-onset colorectal cancer in the North East of Scotland: survival, clinico-pathological features and genetics

por Perrott, Sarah, Laurie, Kirsten, Laws, Kirsten, Johnes, Annie, Miedzybrodzka, Zosia, Samuel, Leslie
Publicado 2020

Oral antibiotic use and early-onset colorectal cancer: findings from a case-control study using a national clinical database

por McDowell, Ronald, Perrott, Sarah, Murchie, Peter, Cardwell, Christopher, Hughes, Carmel, Samuel, Leslie
Publicado 2021

Increased Lymph Node Yield in Colorectal Cancer Is Not Necessarily Associated with a Greater Number of Lymph Node Positive Cancers

por O'Shea, Aisling, Aly, Omar, Parnaby, Craig N., Loudon, Malcolm A., Samuel, Leslie M., Murray, Graeme I.
Publicado 2014

Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA)

por Convertino, Matteo, Church, Timothy R, Olsen, Geary W, Liu, Yang, Doyle, Eddie, Elcombe, Clifford R, Barnett, Anna L, Samuel, Leslie M, MacPherson, Iain R, Evans, Thomas R J
Publicado 2018

Developing a community-based intervention to improve quality of life in people with colorectal cancer: a complex intervention development study

por Gray, Nicola M, Allan, Julia L, Murchie, Peter, Browne, Susan, Hall, Susan, Hubbard, Gill, Johnston, Marie, Lee, Amanda J, McKinley, Aileen, Macleod, Una, Presseau, Justin, Samuel, Leslie, Wyke, Sally, Campbell, Neil C
Publicado 2013

Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial

por Adams, Richard, Brown, Ewan, Brown, Louise, Butler, Rachel, Falk, Stephen, Fisher, David, Kaplan, Richard, Quirke, Phil, Richman, Susan, Samuel, Leslie, Seligmann, Jenny, Seymour, Matt, Shiu, Kai Keen, Wasan, Harpreet, Wilson, Richard, Maughan, Tim
Publicado 2017

APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling

por Petty, Russell D, Samuel, Leslie M, Murray, Graeme I, MacDonald, Graham, O'Kelly, Terrence, Loudon, Malcolm, Binnie, Norman, Aly, Emad, McKinlay, Aileen, Wang, Weiguang, Gilbert, Fiona, Semple, Scot, Collie-Duguid, Elaina SR
Publicado 2009

Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

por Brown, Louise C, Graham, Janet, Fisher, David, Adams, Richard, Seligmann, Jenny, Seymour, Matthew, Kaplan, Richard, Yates, Emma, Parmar, Mahesh, Richman, Susan D, Quirke, Philip, Butler, Rachel, Shiu, Kaikeen, Middleton, Gary, Samuel, Leslie, Wilson, Richard H, Maughan, Timothy S
Publicado 2022

Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations

por Gollins, Simon, West, Nick, Sebag-Montefiore, David, Myint, Arthur Sun, Saunders, Mark, Susnerwala, Shabbir, Quirke, Phil, Essapen, Sharadah, Samuel, Leslie, Sizer, Bruce, Worlding, Jane, Southward, Katie, Hemmings, Gemma, Tinkler-Hundal, Emma, Taylor, Morag, Bottomley, Daniel, Chambers, Philip, Lawrie, Emma, Lopes, Andre, Beare, Sandy
Publicado 2017

Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT)

por Hanna, Catherine R., O’Cathail, Sean M., Graham, Janet S., Saunders, Mark, Samuel, Leslie, Harrison, Mark, Devlin, Lynsey, Edwards, Joanne, Gaya, Daniel R., Kelly, Caroline A., Lewsley, Liz-Anne, Maka, Noori, Morrison, Paula, Dinnett, Louise, Dillon, Susan, Gourlay, Jacqueline, Platt, Jonathan J., Thomson, Fiona, Adams, Richard A., Roxburgh, Campbell S. D.
Publicado 2021

Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial

por Adams, Richard A., Fisher, David J., Graham, Janet, Seligmann, Jenny F., Seymour, Matthew, Kaplan, Richard, Yates, Emma, Parmar, Mahesh, Richman, Susan D., Quirke, Philip, Butler, Rachel, Brown, Ewan, Collinson, Fiona, Falk, Stephen, Wasan, Harpreet, Shiu, Kai-Keen, Middleton, Gary, Samuel, Leslie, Wilson, Richard H., Brown, Louise C., Maughan, Timothy S.
Publicado 2021

Correction to: Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT)

por Hanna, Catherine R., O’Cathail, Sean M., Graham, Janet S., Saunders, Mark, Samuel, Leslie, Harrison, Mark, Devlin, Lynsey, Edwards, Joanne, Gaya, Daniel R., Kelly, Caroline A., Lewsley, Liz-Anne, Maka, Noori, Morrison, Paula, Dinnett, Louise, Dillon, Susan, Gourlay, Jacqueline, Platt, Jonathan J., Thomson, Fiona, Adams, Richard A., Roxburgh, Campbell S. D.
Publicado 2021

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

por Sirinukunwattana, Korsuk, Domingo, Enric, Richman, Susan D, Redmond, Keara L, Blake, Andrew, Verrill, Clare, Leedham, Simon J, Chatzipli, Aikaterini, Hardy, Claire, Whalley, Celina M, Wu, Chieh-hsi, Beggs, Andrew D, McDermott, Ultan, Dunne, Philip D, Meade, Angela, Walker, Steven M, Murray, Graeme I, Samuel, Leslie, Seymour, Matthew, Tomlinson, Ian, Quirke, Phil, Maughan, Timothy, Rittscher, Jens, Koelzer, Viktor H
Publicado 2021

The McCAVE Trial: Vanucizumab plus mFOLFOX‐6 Versus Bevacizumab plus mFOLFOX‐6 in Patients with Previously Untreated Metastatic Colorectal Carcinoma (mCRC)

por Bendell, Johanna C., Sauri, Tamara, Gracián, Antonio Cubillo, Alvarez, Rafael, López‐López, Carlos, García‐Alfonso, Pilar, Hussein, Maen, Miron, Maria‐Luisa Limon, Cervantes, Andrés, Montagut, Clara, Vivas, Cristina Santos, Bessudo, Alberto, Plezia, Patricia, Moons, Veerle, Andel, Johannes, Bennouna, Jaafar, van der Westhuizen, Andre, Samuel, Leslie, Rossomanno, Simona, Boetsch, Christophe, Lahr, Angelika, Franjkovic, Izolda, Heil, Florian, Lechner, Katharina, Krieter, Oliver, Hurwitz, Herbert
Publicado 2019

Transcriptional Subtyping and CD8 Immunohistochemistry Identifies Patients With Stage II and III Colorectal Cancer With Poor Prognosis Who Benefit From Adjuvant Chemotherapy

por Allen, Wendy L., Dunne, Philip D., McDade, Simon, Scanlon, Enya, Loughrey, Maurice, Coleman, Helen G., McCann, Christopher, McLaughlin, Kristy, Nemeth, Zsuzsanna, Syed, Najeeb Ashraf, Jithesh, Puthen Veettil, Arthur, Ken, Wilson, Richard, Coyle, Vicky M., McArt, Darragh, Murray, Graeme I., Samuel, Leslie, Nuciforo, Paolo, Jimenez, Jose, Argiles, Guillem, Dienstmann, Rodrigo, Tabernero, Josef, Picariello, Lucia, Messerini, Luca, Nobili, Stefania, Mini, Enrico, Sheahan, Kieran, Ryan, Elizabeth, Johnston, Patrick G., Van Schaeybroeck, Sandra, Lawler, Mark, Longley, Daniel B.
Publicado 2018