Human iPSCs as Model Systems for BMP-Related Rare Diseases

por Sánchez-Duffhues, Gonzalo, Hiepen, Christian
Publicado 2023

The therapeutic potential of targeting the endothelial-to-mesenchymal transition

por Man, Shirley, Sanchez Duffhues, Gonzalo, ten Dijke, Peter, Baker, David
Publicado 2018

Involvement of inflammation and its related microRNAs in hepatocellular carcinoma

por Jin, Ke, Li, Tong, Sánchez-Duffhues, Gonzalo, Zhou, Fangfang, Zhang, Long
Publicado 2016

TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering

por Ma, Jin, Sanchez-Duffhues, Gonzalo, Goumans, Marie-José, ten Dijke, Peter
Publicado 2020

TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases

por Pardali, Evangelia, Sanchez-Duffhues, Gonzalo, Gomez-Puerto, Maria Catalina, ten Dijke, Peter
Publicado 2017

Sex-biased TGFβ signalling in pulmonary arterial hypertension

por Wits, Marius, Becher, Clarissa, de Man, Frances, Sanchez-Duffhues, Gonzalo, Goumans, Marie-José
Publicado 2023

Bone morphogenetic protein receptor signal transduction in human disease

por Gomez‐Puerto, Maria Catalina, Iyengar, Prasanna Vasudevan, García de Vinuesa, Amaya, ten Dijke, Peter, Sanchez‐Duffhues, Gonzalo
Publicado 2018

Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva

por Ventura, Francesc, Williams, Eleanor, Ikeya, Makoto, Bullock, Alex N., ten Dijke, Peter, Goumans, Marie-José, Sanchez-Duffhues, Gonzalo
Publicado 2021

Activin A and ALK4 Identified as Novel Regulators of Epithelial to Mesenchymal Transition (EMT) in Human Epicardial Cells

por Dronkers, Esther, van Herwaarden, Tessa, van Brakel, Thomas J, Sanchez-Duffhues, Gonzalo, Goumans, Marie-José, Smits, Anke M
Publicado 2021

TGF-Beta Induces Activin A Production in Dermal Fibroblasts Derived from Patients with Fibrodysplasia Ossificans Progressiva

por de Ruiter, Ruben D., Wisse, Lisanne E., Schoenmaker, Ton, Yaqub, Maqsood, Sánchez-Duffhues, Gonzalo, Eekhoff, E. Marelise W., Micha, Dimitra
Publicado 2023

Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors

por Ma, Jin, Ren, Jiang, Thorikay, Midory, van Dinther, Maarten, Sanchez-Duffhues, Gonzalo, Caradec, Josselin, Benderitter, Pascal, Hoflack, Jan, ten Dijke, Peter
Publicado 2021

TGF-β-Induced Endothelial to Mesenchymal Transition Is Determined by a Balance Between SNAIL and ID Factors

por Ma, Jin, van der Zon, Gerard, Gonçalves, Manuel A. F. V., van Dinther, Maarten, Thorikay, Midory, Sanchez-Duffhues, Gonzalo, ten Dijke, Peter
Publicado 2021

Antisense-Oligonucleotide Mediated Exon Skipping in Activin-Receptor-Like Kinase 2: Inhibiting the Receptor That Is Overactive in Fibrodysplasia Ossificans Progressiva

por Shi, SongTing, Cai, Jie, de Gorter, David J. J., Sanchez-Duffhues, Gonzalo, Kemaladewi, Dwi U., Hoogaars, Willem M. H., Aartsma-Rus, Annemieke, ’t Hoen, Peter A. C., ten Dijke, Peter
Publicado 2013

Endothelial Colony Forming Cells as an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve

por van de Pol, Vera, Bons, Lidia R., Lodder, Kirsten, Kurakula, Konda Babu, Sanchez-Duffhues, Gonzalo, Siebelink, Hans-Marc J., Roos-Hesselink, Jolien W., DeRuiter, Marco C., Goumans, Marie-José
Publicado 2019

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

por Garcia de Vinuesa, Amaya, Sanchez‐Duffhues, Gonzalo, Blaney‐Davidson, Esmeralda, van Caam, Arjan, Lodder, Kirsten, Ramos, Yolande, Kloppenburg, Margreet, Meulenbelt, Ingrid, van der Kraan, Peter, Goumans, Marie‐José, ten Dijke, Peter
Publicado 2021

Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

por Sánchez‐Duffhues, Gonzalo, García de Vinuesa, Amaya, van de Pol, Vera, Geerts, Marlieke E, de Vries, Margreet R, Janson, Stef GT, van Dam, Hans, Lindeman, Jan H., Goumans, Marie‐José, ten Dijke, Peter
Publicado 2019

Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells

por Szulcek, Robert, Sanchez-Duffhues, Gonzalo, Rol, Nina, Pan, Xiaoke, Tsonaka, Roula, Dickhoff, Chris, Yung, Lai Ming, Manz, Xue D., Kurakula, Kondababu, Kiełbasa, Szymon M., Mei, Hailiang, Timens, Wim, Yu, Paul B., Bogaard, Harm-Jan, Goumans, Marie-José
Publicado 2020

Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva‐Derived Endothelial Cells

por Sánchez‐Duffhues, Gonzalo, Williams, Eleanor, Benderitter, Pascal, Orlova, Valeria, van Wijhe, Michiel, Garcia de Vinuesa, Amaya, Kerr, Georgina, Caradec, Josselin, Lodder, Kirsten, de Boer, Hetty C., Goumans, Marie‐José, Eekhoff, Elisabeth M W, Morales‐Piga, Antonio, Bachiller‐Corral, Javier, Koolwijk, Pieter, Bullock, Alex N., Hoflack, Jan, ten Dijke, Peter
Publicado 2019

Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

por Fortin, Jerome, Tian, Ruxiao, Zarrabi, Ida, Hill, Graham, Williams, Eleanor, Sanchez-Duffhues, Gonzalo, Thorikay, Midory, Ramachandran, Parameswaran, Siddaway, Robert, Wong, Jong Fu, Wu, Annette, Apuzzo, Lorraine N., Haight, Jillian, You-Ten, Annick, Snow, Bryan E., Wakeham, Andrew, Goldhamer, David J., Schramek, Daniel, Bullock, Alex N., Dijke, Peter ten, Hawkins, Cynthia, Mak, Tak W.
Publicado 2020

Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop

por de Ruiter, Ruben D., Smilde, Bernard J., Pals, Gerard, Bravenboer, Nathalie, Knaus, Petra, Schoenmaker, Ton, Botman, Esmée, Sánchez-Duffhues, Gonzalo, Pacifici, Maurizio, Pignolo, Robert J., Shore, Eileen M., van Egmond, Marjolein, Van Oosterwyck, Hans, Kaplan, Frederick S., Hsiao, Edward C., Yu, Paul B., Bocciardi, Renata, De Cunto, Carmen Laura, Longo Ribeiro Delai, Patricia, de Vries, Teun J., Hilderbrandt, Susanne, Jaspers, Richard T., Keen, Richard, Koolwijk, Peter, Morhart, Rolf, Netelenbos, Jan C., Rustemeyer, Thomas, Scott, Christiaan, Stockklausner, Clemens, ten Dijke, Peter, Triffit, James, Ventura, Francesc, Ravazzolo, Roberto, Micha, Dimitra, Eekhoff, Elisabeth M. W.
Publicado 2021