Generation and proof-of-concept for allogeneic CD123 CAR-Delta One T (DOT) cells in acute myeloid leukemia

por Sánchez Martínez, Diego, Tirado, Néstor, Mensurado, Sofia, Martínez-Moreno, Alba, Romecín, Paola, Gutiérrez Agüera, Francisco, Correia, Daniel V, Silva-Santos, Bruno, Menéndez, Pablo
Publicado 2022

Enforced sialyl‐Lewis‐X (sLeX) display in E‐selectin ligands by exofucosylation is dispensable for CD19‐CAR T‐cell activity and bone marrow homing

por Sánchez‐Martínez, Diego, Gutiérrez‐Agüera, Francisco, Romecin, Paola, Vinyoles, Meritxell, Palomo, Marta, Tirado, Néstor, Zanetti, Samanta Romina, Juan, Manel, Carlet, Michela, Jeremias, Irmela, Menéndez, Pablo
Publicado 2021

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

por Núñez, David, Comas, Laura, Lanuza, Pilar M., Sánchez-Martinez, Diego, Pérez-Hernández, Marta, Catalán, Elena, Domingo, María Pilar, Velázquez-Campoy, Adrián, Pardo, Julián, Gálvez, Eva M.
Publicado 2017

CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity

por Bueno, Clara, Velasco-Hernandez, Talia, Gutiérrez-Agüera, Francisco, Zanetti, Samanta Romina, Baroni, Matteo L., Sánchez-Martínez, Diego, Molina, Oscar, Closa, Adria, Agraz-Doblás, Antonio, Marín, Pedro, Eyras, Eduardo, Varela, Ignacio, Menéndez, Pablo
Publicado 2019

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells

por Sánchez-Martínez, Diego, Lanuza, Pilar M., Gómez, Natalia, Muntasell, Aura, Cisneros, Elisa, Moraru, Manuela, Azaceta, Gemma, Anel, Alberto, Martínez-Lostao, Luis, Villalba, Martin, Palomera, Luis, Vilches, Carlos, García Marco, José A., Pardo, Julián
Publicado 2016

Efficient preclinical treatment of cortical T cell acute lymphoblastic leukemia with T lymphocytes secreting anti-CD1a T cell engagers

por Jiménez-Reinoso, Anaïs, Tirado, Néstor, Martinez-Moreno, Alba, Díaz, Víctor M, García-Peydró, Marina, Hangiu, Oana, Díez-Alonso, Laura, Albitre, Ángela, Penela, Petronila, Toribio, Maria L, Menéndez, Pablo, Álvarez-Vallina, Luis, Sánchez Martínez, Diego
Publicado 2022

Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance

por Calvo, Tania, Reina-Ortiz, Chantal, Giraldos, David, Gascón, María, Woods, Daniel, Asenjo, Judit, Marco-Brualla, Joaquín, Azaceta, Gemma, Izquierdo, Isabel, Palomera, Luis, Sánchez-Martínez, Diego, Marzo, Isabel, Naval, Javier, Vilches, Carlos, Villalba, Martín, Anel, Alberto
Publicado 2020

NG2 antigen is a therapeutic target for MLL-rearranged B-cell acute lymphoblastic leukemia

por Lopez-Millan, Belen, Sanchéz-Martínez, Diego, Roca-Ho, Heleia, Gutiérrez-Agüera, Francisco, Molina, Oscar, Diaz de la Guardia, Rafael, Torres-Ruiz, Raúl, Fuster, Jose Luís, Ballerini, Paola, Suessbier, Ute, Nombela-Arrieta, Cesar, Bueno, Clara, Menéndez, Pablo
Publicado 2019

Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope

por Velasco-Hernandez, Talia, Zanetti, Samanta Romina, Roca-Ho, Heleia, Gutierrez-Aguera, Francisco, Petazzi, Paolo, Sánchez-Martínez, Diego, Molina, Oscar, Baroni, Matteo Libero, Fuster, Jose Luis, Ballerini, Paola, Bueno, Clara, Fernandez-Fuentes, Narcis, Engel, Pablo, Menendez, Pablo
Publicado 2020

Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors

por Sanchez-Martinez, Diego, Allende-Vega, Nerea, Orecchioni, Stefania, Talarico, Giovanna, Cornillon, Amelie, Vo, Dang-Nghiem, Rene, Celine, Lu, Zhao-Yang, Krzywinska, Ewelina, Anel, Alberto, Galvez, Eva M., Pardo, Julian, Robert, Bruno, Martineau, Pierre, Hicheri, Yosr, Bertolini, Francesco, Cartron, Guillaume, Villalba, Martin
Publicado 2018

A novel and efficient tandem CD19- and CD22-directed CAR for B cell ALL

por Zanetti, Samanta Romina, Velasco-Hernandez, Talia, Gutierrez-Agüera, Francisco, Díaz, Víctor M., Romecín, Paola Alejandra, Roca-Ho, Heleia, Sánchez-Martínez, Diego, Tirado, Néstor, Baroni, Matteo Libero, Petazzi, Paolo, Torres-Ruiz, Raúl, Molina, Oscar, Bataller, Alex, Fuster, José Luis, Ballerini, Paola, Juan, Manel, Jeremias, Irmela, Bueno, Clara, Menéndez, Pablo
Publicado 2022

41BB-based and CD28-based CD123-redirected T-cells ablate human normal hematopoiesis in vivo

por Baroni, Matteo Libero, Sanchez Martinez, Diego, Gutierrez Aguera, Francisco, Roca Ho, Heleia, Castella, Maria, Zanetti, Samanta Romina, Velasco Hernandez, Talia, Diaz de la Guardia, Rafael, Castaño, Julio, Anguita, Eduardo, Vives, Susana, Nomdedeu, Josep, Lapillone, Helene, Bras, Anne E, van der Velden, Vincent H J, Junca, Jordi, Marin, Pedro, Bataller, Alex, Esteve, Jordi, Vick, Binje, Jeremias, Irmela, Lopez, Angel, Sorigue, Marc, Bueno, Clara, Menendez, Pablo
Publicado 2020

Functional annotation of human long noncoding RNAs via molecular phenotyping

por Ramilowski, Jordan A., Yip, Chi Wai, Agrawal, Saumya, Chang, Jen-Chien, Ciani, Yari, Kulakovskiy, Ivan V., Mendez, Mickaël, Ooi, Jasmine Li Ching, Ouyang, John F., Parkinson, Nick, Petri, Andreas, Roos, Leonie, Severin, Jessica, Yasuzawa, Kayoko, Abugessaisa, Imad, Akalin, Altuna, Antonov, Ivan V., Arner, Erik, Bonetti, Alessandro, Bono, Hidemasa, Borsari, Beatrice, Brombacher, Frank, Cameron, Christopher J.F., Cannistraci, Carlo Vittorio, Cardenas, Ryan, Cardon, Melissa, Chang, Howard, Dostie, Josée, Ducoli, Luca, Favorov, Alexander, Fort, Alexandre, Garrido, Diego, Gil, Noa, Gimenez, Juliette, Guler, Reto, Handoko, Lusy, Harshbarger, Jayson, Hasegawa, Akira, Hasegawa, Yuki, Hashimoto, Kosuke, Hayatsu, Norihito, Heutink, Peter, Hirose, Tetsuro, Imada, Eddie L., Itoh, Masayoshi, Kaczkowski, Bogumil, Kanhere, Aditi, Kawabata, Emily, Kawaji, Hideya, Kawashima, Tsugumi, Kelly, S. Thomas, Kojima, Miki, Kondo, Naoto, Koseki, Haruhiko, Kouno, Tsukasa, Kratz, Anton, Kurowska-Stolarska, Mariola, Kwon, Andrew Tae Jun, Leek, Jeffrey, Lennartsson, Andreas, Lizio, Marina, López-Redondo, Fernando, Luginbühl, Joachim, Maeda, Shiori, Makeev, Vsevolod J., Marchionni, Luigi, Medvedeva, Yulia A., Minoda, Aki, Müller, Ferenc, Muñoz-Aguirre, Manuel, Murata, Mitsuyoshi, Nishiyori, Hiromi, Nitta, Kazuhiro R., Noguchi, Shuhei, Noro, Yukihiko, Nurtdinov, Ramil, Okazaki, Yasushi, Orlando, Valerio, Paquette, Denis, Parr, Callum J.C., Rackham, Owen J.L., Rizzu, Patrizia, Sánchez Martinez, Diego Fernando, Sandelin, Albin, Sanjana, Pillay, Semple, Colin A.M., Shibayama, Youtaro, Sivaraman, Divya M., Suzuki, Takahiro, Szumowski, Suzannah C., Tagami, Michihira, Taylor, Martin S., Terao, Chikashi, Thodberg, Malte, Thongjuea, Supat, Tripathi, Vidisha, Ulitsky, Igor, Verardo, Roberto, Vorontsov, Ilya E., Yamamoto, Chinatsu, Young, Robert S., Baillie, J. Kenneth, Forrest, Alistair R.R., Guigó, Roderic, Hoffman, Michael M., Hon, Chung Chau, Kasukawa, Takeya, Kauppinen, Sakari, Kere, Juha, Lenhard, Boris, Schneider, Claudio, Suzuki, Harukazu, Yagi, Ken, de Hoon, Michiel J.L., Shin, Jay W., Carninci, Piero
Publicado 2020