Forced expression of the DEK-NUP214 fusion protein promotes proliferation dependent on upregulation of mTOR

por Sandén, Carl, Ageberg, Malin, Petersson, Jessica, Lennartsson, Andreas, Gullberg, Urban
Publicado 2013

The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation

por Sandén, Carl, Järvstråt, Linnea, Lennartsson, Andreas, Brattås, Per Ludvik, Nilsson, Björn, Gullberg, Urban
Publicado 2014

Transcriptional profiling demonstrates altered characteristics of CD8 (+) cytotoxic T‐cells and regulatory T‐cells in TP53‐mutated acute myeloid leukemia

por Abolhalaj, Milad, Sincic, Viktor, Lilljebjörn, Henrik, Sandén, Carl, Aab, Alar, Hägerbrand, Karin, Ellmark, Peter, Borrebaeck, Carl A. K., Fioretos, Thoas, Lundberg, Kristina
Publicado 2022

CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting

por Landberg, Niklas, von Palffy, Sofia, Askmyr, Maria, Lilljebjörn, Henrik, Sandén, Carl, Rissler, Marianne, Mustjoki, Satu, Hjorth-Hansen, Henrik, Richter, Johan, Ågerstam, Helena, Järås, Marcus, Fioretos, Thoas
Publicado 2018

Combinatorial molecule screening identified a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells

por Hultmark, Simon, Baudet, Aurélie, Schmiderer, Ludwig, Prabhala, Pavan, Palma-Tortosa, Sara, Sandén, Carl, Fioretos, Thoas, Sasidharan, Rajkumar, Larsson, Christer, Lehmann, Sören, Juliusson, Gunnar, Ek, Fredrik, Magnusson, Mattias
Publicado 2020

Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations

por Subramaniam, Agatheeswaran, Sandén, Carl, Moura-Castro, Larissa, Žemaitis, Kristijonas, Schmiderer, Ludwig, Baudet, Aurelie, Bäckström, Alexandra, Arvidsson, Elin, Hultmark, Simon, Miharada, Natsumi, Magnusson, Mattias, Paulsson, Kajsa, Fioretos, Thoas, Larsson, Jonas
Publicado 2022

Clonal competition within complex evolutionary hierarchies shapes AML over time

por Sandén, Carl, Lilljebjörn, Henrik, Orsmark Pietras, Christina, Henningsson, Rasmus, Saba, Karim H., Landberg, Niklas, Thorsson, Hanna, von Palffy, Sofia, Peña-Martinez, Pablo, Högberg, Carl, Rissler, Marianne, Gisselsson, David, Lazarevic, Vladimir, Juliusson, Gunnar, Ågerstam, Helena, Fioretos, Thoas
Publicado 2020

A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells

por von Palffy, Sofia, Landberg, Niklas, Sandén, Carl, Zacharaki, Dimitra, Shah, Mansi, Nakamichi, Naoto, Hansen, Nils, Askmyr, Maria, Lilljebjörn, Henrik, Rissler, Marianne, Karlsson, Christine, Scheding, Stefan, Richter, Johan, Eaves, Connie J., Bhatia, Ravi, Järås, Marcus, Fioretos, Thoas
Publicado 2020

The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML

por von Palffy, Sofia, Thorsson, Hanna, Peña-Martínez, Pablo, Puente-Moncada, Noelia, Sandén, Carl, Blom, Anna M., Henningsson, Rasmus, Juliusson, Gunnar, King, Ben, Landberg, Niklas, Lazarevic, Vladimir, Orsmark-Pietras, Christina, Rissler, Marianne, Rissler, Vendela, Ågerstam, Helena, Järås, Marcus, Lilljebjörn, Henrik, Fioretos, Thoas
Publicado 2022