The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo

por Booth, Laurence, Roberts, Jane L., Sander, Cindy, Lee, John, Kirkwood, John M., Poklepovic, Andrew, Dent, Paul
Publicado 2017

Predicting Metastasis in Melanoma by Enumerating Circulating Tumor Cells Using Photoacoustic Flow Cytometry

por Edgar, Robert H., Tarhini, Ahmad, Sander, Cindy, Sanders, Martin E., Cook, Justin L., Viator, John A.
Publicado 2020

Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma

por Tarhini, Ahmad A., Zahoor, Haris, Lin, Yan, Malhotra, Usha, Sander, Cindy, Butterfield, Lisa H., Kirkwood, John M.
Publicado 2015

High-dose interleukin-2 (HD IL-2) for advanced melanoma: a single center experience from the University of Pittsburgh Cancer Institute

por Davar, Diwakar, Ding, Fei, Saul, Melissa, Sander, Cindy, Tarhini, Ahmad A., Kirkwood, John M., Tawbi, Hussein A.
Publicado 2017

A four-marker signature of TNF-RII, TGF-α, TIMP-1 and CRP is prognostic of worse survival in high-risk surgically resected melanoma

por Tarhini, Ahmad A, Lin, Yan, Yeku, Oladapo, LaFramboise, William A, Ashraf, Madeeha, Sander, Cindy, Kirkwood, John M, Lee, Sandra
Publicado 2014

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8(+) T cell dysfunction in melanoma patients

por Fourcade, Julien, Sun, Zhaojun, Benallaoua, Mourad, Guillaume, Philippe, Luescher, Immanuel F., Sander, Cindy, Kirkwood, John M., Kuchroo, Vijay, Zarour, Hassane M.
Publicado 2010

The levels of mutant K-RAS and mutant N-RAS are rapidly reduced in a Beclin1 / ATG5 -dependent fashion by the irreversible ERBB1/2/4 inhibitor neratinib

por Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Kirkwood, John, Sander, Cindy, Avogadri-Connors, Francesca, Cutler Jr, Richard E., Lalani, Alshad S., Dent, Paul
Publicado 2017

Multiple primary melanoma in association with other personal and familial cancers

por Yang, Xi, Karapetyan, Lilit, Huang, Ziyu, Knight, Andrew D., Rajendran, Sneha, Sander, Cindy, Minnier, Christopher P., Wilson, Melissa J., Kirkwood, John M.
Publicado 2022

Tumor associated PD-L1 expression pattern in microscopically tumor positive sentinel lymph nodes in patients with melanoma

por Tarhini, Ahmad A., Zahoor, Haris, Yearley, Jennifer H., Gibson, Christopher, Rahman, Zahra, Dubner, Rachel, Rao, Uma N. M., Sander, Cindy, Kirkwood, John M.
Publicado 2015

Pro-Inflammatory Cytokines Predict Relapse-Free Survival after One Month of Interferon-α but Not Observation in Intermediate Risk Melanoma Patients

por Tarhini, Ahmad A., Lin, Yan, Zahoor, Haris, Shuai, Yongli, Butterfield, Lisa H., Ringquist, Steven, Gogas, Helen, Sander, Cindy, Lee, Sandra, Agarwala, Sanjiv S., Kirwood, John M.
Publicado 2015

Immune Monitoring of the Circulation and the Tumor Microenvironment in Patients with Regionally Advanced Melanoma Receiving Neoadjuvant Ipilimumab

por Tarhini, Ahmad A., Edington, Howard, Butterfield, Lisa H., Lin, Yan, Shuai, Yongli, Tawbi, Hussein, Sander, Cindy, Yin, Yan, Holtzman, Matthew, Johnson, Jonas, Rao, Uma N. M., Kirkwood, John M.
Publicado 2014

CD56(dim) CD16(−) Natural Killer Cell Profiling in Melanoma Patients Receiving a Cancer Vaccine and Interferon-α

por Vujanovic, Lazar, Chuckran, Christopher, Lin, Yan, Ding, Fei, Sander, Cindy A., Santos, Patricia M., Lohr, Joel, Mashadi-Hossein, Afshin, Warren, Sarah, White, Andy, Huang, Alan, Kirkwood, John M., Butterfield, Lisa H.
Publicado 2019

Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study

por Augustin, Ryan C., Huang, Ziyu, Ding, Fei, Zhai, Shuyan, McArdle, Jennifer, Santisi, Anthony, Davis, Michael, Sander, Cindy, Davar, Diwakar, Kirkwood, John M., Delgoffe, Greg M., Warner, Allison Betof, Najjar, Yana G.
Publicado 2023

Sentinel Lymph Node Gene Expression Signature Predicts Recurrence-Free Survival in Cutaneous Melanoma

por Karapetyan, Lilit, Gooding, William, Li, Aofei, Yang, Xi, Knight, Andrew, Abushukair, Hassan M., Vargas De Stefano, Danielle, Sander, Cindy, Karunamurthy, Arivarasan, Panelli, Monica, Storkus, Walter J., Tarhini, Ahmad A., Kirkwood, John M.
Publicado 2022

Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors

por Sander, Cindy A., Rush, Elizabeth A., Shi, Jian, Arantes, Lidia M. R. B., Tesi, Raymond J., Ross, Mark A., Calderon, Michael J., Watkins, Simon C., Kirkwood, John M., Ferris, Robert L., Butterfield, Lisa H., Vujanovic, Lazar
Publicado 2022

Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma

por Augustin, Ryan C, Newman, Sarah, Li, Aofei, Joy, Marion, Lyons, Maureen, Pham, Mary P, Lucas, Peter, Smith, Katelyn, Sander, Cindy, Isett, Brian, Davar, Diwakar, Najjar, Yana G, Zarour, Hassane M, Kirkwood, John M, Luke, Jason John, Bao, Riyue
Publicado 2023

Development and Narrow Validation of Computer Vision Approach to Facilitate Assessment of Change in Pigmented Cutaneous Lesions

por Maguire, William F., Haley, Paul H., Dietz, Catherine M., Hoffelder, Mike, Brandt, Clara S., Joyce, Robin, Fitzgerald, Georgia, Minnier, Christopher, Sander, Cindy, Ferris, Laura K., Paragh, Gyorgy, Arbesman, Joshua, Wang, Hong, Mitchell, Kevin J., Hughes, Ellen K., Kirkwood, John M.
Publicado 2023

Mitochondrial Respiration - An Important Therapeutic Target in Melanoma

por Barbi de Moura, Michelle, Vincent, Garret, Fayewicz, Shelley L., Bateman, Nicholas W., Hood, Brian L., Sun, Mai, Suhan, Joseph, Duensing, Stefan, Yin, Yan, Sander, Cindy, Kirkwood, John M., Becker, Dorothea, Conrads, Thomas P., Van Houten, Bennett, Moschos, Stergios J.
Publicado 2012

Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy

por Lau, Eric, Sedy, John, Sander, Cindy, Shaw, Misa Austin, Feng, Yongmei, Scortegagna, Marzia, Claps, Giuseppina, Robinson, Steven, Cheng, Phil, Srivas, Rohith, Soonthornvacharin, Stephen, Ideker, Trey, Bosenberg, Marcus, Gonzalez, Réné, Robinson, William, Chanda, Sumit, Ware, Carl, Dummer, Reinhard, Hoon, Dave, Kirkwood, John M., Ronai, Ze'ev A
Publicado 2015

Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes

por Karapetyan, Lilit, AbuShukair, Hassan M., Li, Aofei, Knight, Andrew, Al Bzour, Ayah Nedal, MacFawn, Ian P., Thompson, Zachary J., Chen, Ann, Yang, Xi, Dadey, Rebekah, Karunamurthy, Arivarasan, De Stefano, Danielle Vargas, Sander, Cindy, Kunning, Sheryl R., Najjar, Yana G., Davar, Diwakar, Luke, Jason J., Gooding, William, Bruno, Tullia C., Kirkwood, John M., Storkus, Walter J.
Publicado 2023