The search for RNA-binding proteins: a technical and interdisciplinary challenge

por Smith, Jeffrey M., Sandow, Jarrod J., Webb, Andrew I.
Publicado 2021

Enzymatic Characterization of Wild-Type and Mutant Janus Kinase 1

por Liau, Nicholas P. D., Laktyushin, Artem, Morris, Rhiannon, Sandow, Jarrod J., Nicola, Nicos A., Kershaw, Nadia J., Babon, Jeffrey J.
Publicado 2019

K‐29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis

por Farooq, Ammara Usman, Gembus, Kelly, Sandow, Jarrod J., Webb, Andrew, Mathivanan, Suresh, Manning, Jantina A., Shah, Sonia S., Foot, Natalie J., Kumar, Sharad
Publicado 2022

Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling

por Meng, Yanxiang, Horne, Christopher R., Samson, Andre L., Dagley, Laura F., Young, Samuel N., Sandow, Jarrod J., Czabotar, Peter E., Murphy, James M.
Publicado 2022

Phosphorylation by Aurora B kinase regulates caspase-2 activity and function

por Lim, Yoon, De Bellis, Dylan, Sandow, Jarrod J., Capalbo, Luisa, D’Avino, Pier Paolo, Murphy, James M., Webb, Andrew I., Dorstyn, Loretta, Kumar, Sharad
Publicado 2020

Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain

por Moecking, Jonas, Laohamonthonkul, Pawat, Meşe, Kubilay, Hagelueken, Gregor, Steiner, Annemarie, Harapas, Cassandra R., Sandow, Jarrod J., Graves, Jonathan D., Masters, Seth L., Geyer, Matthias
Publicado 2022

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

por Stutz, Michael D., Ojaimi, Samar, Allison, Cody, Preston, Simon, Arandjelovic, Philip, Hildebrand, Joanne M., Sandow, Jarrod J., Webb, Andrew I., Silke, John, Alexander, Warren S., Pellegrini, Marc
Publicado 2017

How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

por Xu, Yibin, Kirk, Nicholas S., Venugopal, Hariprasad, Margetts, Mai B., Croll, Tristan I., Sandow, Jarrod J., Webb, Andrew I., Delaine, Carlie A., Forbes, Briony E., Lawrence, Michael C.
Publicado 2020

Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation

por Foot, Natalie J., Gonzalez, Macarena B., Gembus, Kelly, Fonseka, Pamali, Sandow, Jarrod J., Nguyen, Thuy Tien, Tran, Diana, Webb, Andrew I., Mathivanan, Suresh, Robker, Rebecca L., Kumar, Sharad
Publicado 2021

CD98 defines a metabolically flexible, proinflammatory subset of low‐density neutrophils in systemic lupus erythematosus

por Martin, Katherine R., Day, Jessica A., Hansen, Jacinta A., D'Silva, Damian B., Wong, Huon L., Garnham, Alexandra, Sandow, Jarrod J., Nijagal, Brunda, Wilson, Nicholas, Wicks, Ian P.
Publicado 2023

A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma

por Pandey, Kirti, Wang, Stacie S., Mifsud, Nicole A., Faridi, Pouya, Davenport, Alexander J., Webb, Andrew I., Sandow, Jarrod J., Ayala, Rochelle, Monje, Michelle, Cross, Ryan S., Ramarathinam, Sri H., Jenkins, Misty R., Purcell, Anthony W.
Publicado 2023

The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs

por Liang, Lung-Yu, Roy, Michael, Horne, Christopher R., Sandow, Jarrod J., Surudoi, Minglyanna, Dagley, Laura F., Young, Samuel N., Dite, Toby, Babon, Jeffrey J., Janes, Peter W., Patel, Onisha, Murphy, James M., Lucet, Isabelle S.
Publicado 2021

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix

por Oliver, Michael R., Horne, Christopher R., Shrestha, Safal, Keown, Jeremy R., Liang, Lung-Yu, Young, Samuel N., Sandow, Jarrod J., Webb, Andrew I., Goldstone, David C., Lucet, Isabelle S., Kannan, Natarajan, Metcalf, Peter, Murphy, James M.
Publicado 2021

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

por Brumatti, Gabriela, Salmanidis, Marika, Kok, Chung H, Bilardi, Rebecca A, Sandow, Jarrod J, Silke, Natasha, Mason, Kylie, Visser, Jolanda, Jabbour, Anissa M, Glaser, Stefan P, Okamoto, Toru, Bouillet, Philippe, D'Andrea, Richard J, Ekert, Paul G
Publicado 2013

Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis

por Meng, Yanxiang, Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Horne, Christopher R., Luo, Cindy, Garnier, Jean-Marc, Liang, Lung-Yu, Cowan, Angus D., Samson, Andre L., Lessene, Guillaume, Sandow, Jarrod J., Czabotar, Peter E., Murphy, James M.
Publicado 2021

SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia

por Brown, Lauren M., Hediyeh-zadeh, Soroor, Sadras, Teresa, Huckstep, Hannah, Sandow, Jarrod J., Bartolo, Ray C., Kosasih, Hansen J., Davidson, Nadia M., Schmidt, Breon, Bjelosevic, Stefan, Johnstone, Ricky, Webb, Andrew I., Khaw, Seong L., Oshlack, Alicia, Davis, Melissa J., Ekert, Paul G.
Publicado 2022

Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues

por Davies, Katherine A., Fitzgibbon, Cheree, Young, Samuel N., Garnish, Sarah E., Yeung, Wayland, Coursier, Diane, Birkinshaw, Richard W., Sandow, Jarrod J., Lehmann, Wil I. L., Liang, Lung-Yu, Lucet, Isabelle S., Chalmers, James D., Patrick, Wayne M., Kannan, Natarajan, Petrie, Emma J., Czabotar, Peter E., Murphy, James M.
Publicado 2020

Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death

por Liu, Lin, Sandow, Jarrod J., Leslie Pedrioli, Deena M., Samson, Andre L., Silke, Natasha, Kratina, Tobias, Ambrose, Rebecca L., Doerflinger, Marcel, Hu, Zhaoqing, Morrish, Emma, Chau, Diep, Kueh, Andrew J., Fitzibbon, Cheree, Pellegrini, Marc, Pearson, Jaclyn S., Hottiger, Michael O., Webb, Andrew I., Lalaoui, Najoua, Silke, John
Publicado 2022

Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis

por Garnish, Sarah E., Meng, Yanxiang, Koide, Akiko, Sandow, Jarrod J., Denbaum, Eric, Jacobsen, Annette V., Yeung, Wayland, Samson, Andre L., Horne, Christopher R., Fitzgibbon, Cheree, Young, Samuel N., Smith, Phoebe P. C., Webb, Andrew I., Petrie, Emma J., Hildebrand, Joanne M., Kannan, Natarajan, Czabotar, Peter E., Koide, Shohei, Murphy, James M.
Publicado 2021

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

por Petrie, Emma J., Sandow, Jarrod J., Jacobsen, Annette V., Smith, Brian J., Griffin, Michael D. W., Lucet, Isabelle S., Dai, Weiwen, Young, Samuel N., Tanzer, Maria C., Wardak, Ahmad, Liang, Lung-Yu, Cowan, Angus D., Hildebrand, Joanne M., Kersten, Wilhelmus J. A., Lessene, Guillaume, Silke, John, Czabotar, Peter E., Webb, Andrew I., Murphy, James M.
Publicado 2018