Biomarker for Ischemic Stroke Using Metabolome: A Clinician Perspective

por Sidorov, Evgeny, Sanghera, Dharambir K., Vanamala, Jairam K. P.
Publicado 2019

Genetic and Cultural Reconstruction of the Migration of an Ancient Lineage

por Mascarenhas, Desmond D., Raina, Anupuma, Aston, Christopher E., Sanghera, Dharambir K.
Publicado 2015

Frequencies of poor metabolizer alleles of 12 pharmacogenomic actionable genes in Punjabi Sikhs of Indian Origin

por Sanghera, Dharambir K., Bejar, Cynthia, Sapkota, Bishwa, Wander, Gurpreet S., Ralhan, Sarju
Publicado 2018

Ethnic differences in ApoC-III concentration and the risk of cardiovascular disease: No evidence for the cardioprotective role of rare/loss of function APOC3 variants in non-Europe...

por Rout, Madhusmita, Lerner, Megan, Blackett, Piers R., Peyton, Marvin D., Stavrakis, Stavros, Sidorov, Evgeny, Sanghera, Dharambir K.
Publicado 2022

Carriers of a novel frame-shift insertion in WNT16a possess elevated pancreatic expression of TCF7L2

por Howard, Eric W, Been, Latonya F, Lerner, Megan, Brackett, Daniel, Lightfoot, Stan, Bullen, Elizabeth C, Sanghera, Dharambir K
Publicado 2013

Targeting IL-23 for the interception of obesity-associated colorectal cancer

por Madka, Venkateshwar, Chiliveru, Srikanth, Panneerselvam, Janani, Pathuri, Gopal, Zhang, Yuting, Stratton, Nicole, Kumar, Nandini, Sanghera, Dharambir K., Rao, Chinthalapally V.
Publicado 2023

Comparison of Acute and Chronic Stage Ischemic Stroke Metabolome with Controls

por Sidorov, Evgeny V., Rout, Madhusmita, Xu, Chao, Larsen, Jordan, Fields, Evan, Apple, Blair, Smith, Kyle, Gordon, David, Chainakul, Juliane, Sanghera, Dharambir
Publicado 2023

Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: A study of 3,310 subjects from India and the US

por Been, Latonya F, Ralhan, Sarju, Wander, Gurpreet S, Mehra, Narinder K, Singh, JaiRup, Mulvihill, John J, Aston, Christopher E, Sanghera, Dharambir K
Publicado 2011

Genome-Wide Linkage Scan to Identify Loci Associated with Type 2 Diabetes and Blood Lipid Phenotypes in the Sikh Diabetes Study

por Sanghera, Dharambir K., Been, Latonya F., Ralhan, Sarju, Wander, Gurpreet S., Mehra, Narinder K., Singh, Jai Rup, Ferrell, Robert E., Kamboh, Mohammed I., Aston, Christopher E.
Publicado 2011

A Replication Study of GWAS-Derived Lipid Genes in Asian Indians: The Chromosomal Region 11q23.3 Harbors Loci Contributing to Triglycerides

por Braun, Timothy R., Been, Latonya F., Singhal, Akhil, Worsham, Jacob, Ralhan, Sarju, Wander, Gurpreet S., Chambers, John C., Kooner, Jaspal S., Aston, Christopher E., Sanghera, Dharambir K.
Publicado 2012

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk

por Sanghera, Dharambir K, Ortega, Lyda, Han, Shizhong, Singh, Jairup, Ralhan, Sarju K, Wander, Gurpreet S, Mehra, Narinder K, Mulvihill, John J, Ferrell, Robert E, Nath, Swapan K, Kamboh, Mohammed I
Publicado 2008

Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in GCKR promote ectopic fat deposition

por Sanghera, Dharambir K., Hopkins, Ruth, Malone-Perez, Megan W., Bejar, Cynthia, Tan, Chengcheng, Mussa, Huda, Whitby, Paul, Fowler, Ben, Rao, Chinthapally V., Fung, KarMing A., Lightfoot, Stan, Frazer, J. Kimble
Publicado 2019

PhenX RISING: real world implementation and sharing of PhenX measures

por McCarty, Catherine A, Huggins, Wayne, Aiello, Allison E, Bilder, Robert M, Hariri, Ahmad, Jernigan, Terry L, Newman, Erik, Sanghera, Dharambir K, Strauman, Timothy J, Zeng, Yi, Ramos, Erin M, Junkins, Heather A
Publicado 2014

Investigation of Genetic Variation Underlying Central Obesity amongst South Asians

por Scott, William R., Zhang, Weihua, Loh, Marie, Tan, Sian-Tsung, Lehne, Benjamin, Afzal, Uzma, Peralta, Juan, Saxena, Richa, Ralhan, Sarju, Wander, Gurpreet S., Bozaoglu, Kiymet, Sanghera, Dharambir K., Elliott, Paul, Scott, James, Chambers, John C., Kooner, Jaspal S.
Publicado 2016

A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans

por Bejar, Cynthia A., Goyal, Shiwali, Afzal, Shoaib, Mangino, Massimo, Zhou, Ang, van der Most, Peter J., Bao, Yanchun, Gupta, Vipin, Smart, Melissa C., Walia, Gagandeep K., Verweij, Niek, Power, Christine, Prabhakaran, Dorairaj, Singh, Jai Rup, Mehra, Narinder K., Wander, Gurpreet S., Ralhan, Sarju, Kinra, Sanjay, Kumari, Meena, de Borst, Martin H., Hyppönen, Elina, Spector, Tim D., Nordestgaard, Børge G., Blackett, Piers R., Sanghera, Dharambir K.
Publicado 2021

APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

por Goyal, Shiwali, Tanigawa, Yosuke, Zhang, Weihua, Chai, Jin-Fang, Almeida, Marcio, Sim, Xueling, Lerner, Megan, Chainakul, Juliane, Ramiu, Jonathan Garcia, Seraphin, Chanel, Apple, Blair, Vaughan, April, Muniu, James, Peralta, Juan, Lehman, Donna M., Ralhan, Sarju, Wander, Gurpreet S., Singh, Jai Rup, Mehra, Narinder K., Sidorov, Evgeny, Peyton, Marvin D., Blackett, Piers R., Curran, Joanne E., Tai, E. Shyong, van Dam, Rob, Cheng, Ching-Yu, Duggirala, Ravindranath, Blangero, John, Chambers, John C., Sabanayagam, Charumathi, Kooner, Jaspal S., Rivas, Manuel A., Aston, Christopher E., Sanghera, Dharambir K.
Publicado 2021

Burden of Type 2 Diabetes and Associated Cardiometabolic Traits and Their Heritability Estimates in Endogamous Ethnic Groups of India: Findings From the INDIGENIUS Consortium

por Venkatesan, Vettriselvi, Lopez-Alvarenga, Juan Carlos, Arya, Rector, Ramu, Deepika, Koshy, Teena, Ravichandran, Umarani, Ponnala, Amaresh Reddy, Sharma, Surendra K., Lodha, Sailesh, Sharma, Krishna K., Shaik, Mahaboob Vali, Resendez, Roy G., Venugopal, Priyanka, R, Parthasarathy, Saju, Noelta, Ezeilo, Juliet A., Bejar, Cynthia, Wander, Gurpreet S., Ralhan, Sarju, Singh, Jai Rup, Mehra, Narinder K., Vadlamudi, Raghavendra Rao, Almeida, Marcio, Mummidi, Srinivas, Natesan, Chidambaram, Blangero, John, Medicherla, Krishna M., Thanikachalam, Sadagopan, Panchatcharam, Thyagarajan Sadras, Kandregula, Dileep Kumar, Gupta, Rajeev, Sanghera, Dharambir K., Duggirala, Ravindranath, Paul, Solomon F. D.
Publicado 2022

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

por Saxena, Richa, Saleheen, Danish, Been, Latonya F., Garavito, Martha L., Braun, Timothy, Bjonnes, Andrew, Young, Robin, Ho, Weang Kee, Rasheed, Asif, Frossard, Philippe, Sim, Xueling, Hassanali, Neelam, Radha, Venkatesan, Chidambaram, Manickam, Liju, Samuel, Rees, Simon D., Ng, Daniel Peng-Keat, Wong, Tien-Yin, Yamauchi, Toshimasa, Hara, Kazuo, Tanaka, Yasushi, Hirose, Hiroshi, McCarthy, Mark I., Morris, Andrew P., Basit, Abdul, Barnett, Anthony H., Katulanda, Prasad, Matthews, David, Mohan, Viswanathan, Wander, Gurpreet S., Singh, Jai Rup, Mehra, Narinder K., Ralhan, Sarju, Kamboh, M. Ilyas, Mulvihill, John J., Maegawa, Hiroshi, Tobe, Kazuyuki, Maeda, Shiro, Cho, Yoon S., Tai, E. Shyong, Kelly, M. Ann, Chambers, John C., Kooner, Jaspal S., Kadowaki, Takashi, Deloukas, Panos, Rader, Daniel J., Danesh, John, Sanghera, Dharambir K.
Publicado 2013

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

por Imamura, Minako, Takahashi, Atsushi, Yamauchi, Toshimasa, Hara, Kazuo, Yasuda, Kazuki, Grarup, Niels, Zhao, Wei, Wang, Xu, Huerta-Chagoya, Alicia, Hu, Cheng, Moon, Sanghoon, Long, Jirong, Kwak, Soo Heon, Rasheed, Asif, Saxena, Richa, Ma, Ronald C. W., Okada, Yukinori, Iwata, Minoru, Hosoe, Jun, Shojima, Nobuhiro, Iwasaki, Minaka, Fujita, Hayato, Suzuki, Ken, Danesh, John, Jørgensen, Torben, Jørgensen, Marit E., Witte, Daniel R., Brandslund, Ivan, Christensen, Cramer, Hansen, Torben, Mercader, Josep M., Flannick, Jason, Moreno-Macías, Hortensia, Burtt, Noël P., Zhang, Rong, Kim, Young Jin, Zheng, Wei, Singh, Jai Rup, Tam, Claudia H. T., Hirose, Hiroshi, Maegawa, Hiroshi, Ito, Chikako, Kaku, Kohei, Watada, Hirotaka, Tanaka, Yasushi, Tobe, Kazuyuki, Kawamori, Ryuzo, Kubo, Michiaki, Cho, Yoon Shin, Chan, Juliana C. N., Sanghera, Dharambir, Frossard, Philippe, Park, Kyong Soo, Shu, Xiao-Ou, Kim, Bong-Jo, Florez, Jose C., Tusié-Luna, Teresa, Jia, Weiping, Tai, E Shyong, Pedersen, Oluf, Saleheen, Danish, Maeda, Shiro, Kadowaki, Takashi
Publicado 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

por Loley, Christina, Alver, Maris, Assimes, Themistocles L., Bjonnes, Andrew, Goel, Anuj, Gustafsson, Stefan, Hernesniemi, Jussi, Hopewell, Jemma C., Kanoni, Stavroula, Kleber, Marcus E., Lau, King Wai, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Nelson, Christopher P., Nikpay, Majid, Qu, Liming, Salfati, Elias, Scholz, Markus, Tukiainen, Taru, Willenborg, Christina, Won, Hong-Hee, Zeng, Lingyao, Zhang, Weihua, Anand, Sonia S., Beutner, Frank, Bottinger, Erwin P., Clarke, Robert, Dedoussis, George, Do, Ron, Esko, Tõnu, Eskola, Markku, Farrall, Martin, Gauguier, Dominique, Giedraitis, Vilmantas, Granger, Christopher B., Hall, Alistair S., Hamsten, Anders, Hazen, Stanley L., Huang, Jie, Kähönen, Mika, Kyriakou, Theodosios, Laaksonen, Reijo, Lind, Lars, Lindgren, Cecilia, Magnusson, Patrik K. E., Marouli, Eirini, Mihailov, Evelin, Morris, Andrew P., Nikus, Kjell, Pedersen, Nancy, Rallidis, Loukianos, Salomaa, Veikko, Shah, Svati H., Stewart, Alexandre F. R., Thompson, John R., Zalloua, Pierre A., Chambers, John C., Collins, Rory, Ingelsson, Erik, Iribarren, Carlos, Karhunen, Pekka J., Kooner, Jaspal S., Lehtimäki, Terho, Loos, Ruth J. F., März, Winfried, McPherson, Ruth, Metspalu, Andres, Reilly, Muredach P., Ripatti, Samuli, Sanghera, Dharambir K., Thiery, Joachim, Watkins, Hugh, Deloukas, Panos, Kathiresan, Sekar, Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, König, Inke R.
Publicado 2016