SoxE group transcription factor Sox8 promotes astrocytic differentiation of neural stem/precursor cells downstream of Nfia

por Takouda, Jun, Katada, Sayako, Imamura, Takuya, Sanosaka, Tsukasa, Nakashima, Kinichi
Publicado 2021

Homologous Recombination-Enhancing Factors Identified by Comparative Transcriptomic Analyses of Pluripotent Stem Cell of Human and Common Marmoset

por Yoshimatsu, Sho, Nakajima, Mayutaka, Qian, Emi, Sanosaka, Tsukasa, Sato, Tsukika, Okano, Hideyuki
Publicado 2022

BMP-induced REST regulates the establishment and maintenance of astrocytic identity

por Kohyama, Jun, Sanosaka, Tsukasa, Tokunaga, Akinori, Takatsuka, Eriko, Tsujimura, Keita, Okano, Hideyuki, Nakashima, Kinichi
Publicado 2010

Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms

por Ideno, Hirosato, Imaizumi, Kent, Shimada, Hiroko, Sanosaka, Tsukasa, Nemoto, Akisa, Kohyama, Jun, Okano, Hideyuki
Publicado 2022

Chromatin remodeler CHD7 targets active enhancer region to regulate cell type-specific gene expression in human neural crest cells

por Sanosaka, Tsukasa, Okuno, Hironobu, Mizota, Noriko, Andoh-Noda, Tomoko, Sato, Miki, Tomooka, Ryo, Banno, Satoe, Kohyama, Jun, Okano, Hideyuki
Publicado 2022

Identification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation

por Ito, Kenji, Sanosaka, Tsukasa, Igarashi, Katsuhide, Ideta-Otsuka, Maky, Aizawa, Akira, Uosaki, Yuichi, Noguchi, Azumi, Arakawa, Hirokazu, Nakashima, Kinichi, Takizawa, Takumi
Publicado 2016

Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb

por Kuwabara, Tomoko, Kagalwala, Mohamedi N, Onuma, Yasuko, Ito, Yuzuru, Warashina, Masaki, Terashima, Kazuyuki, Sanosaka, Tsukasa, Nakashima, Kinichi, Gage, Fred H, Asashima, Makoto
Publicado 2011

Mesenchymal properties of iPSC-derived neural progenitors that generate undesired grafts after transplantation

por Isoda, Miho, Sanosaka, Tsukasa, Tomooka, Ryo, Mabuchi, Yo, Shinozaki, Munehisa, Andoh-Noda, Tomoko, Banno, Satoe, Mizota, Noriko, Yamaguchi, Ryo, Okano, Hideyuki, Kohyama, Jun
Publicado 2023

Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage

por Andoh-Noda, Tomoko, Akamatsu, Wado, Miyake, Kunio, Matsumoto, Takuya, Yamaguchi, Ryo, Sanosaka, Tsukasa, Okada, Yohei, Kobayashi, Tetsuro, Ohyama, Manabu, Nakashima, Kinichi, Kurosawa, Hiroshi, Kubota, Takeo, Okano, Hideyuki
Publicado 2015

Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation

por Someya, Kazue, Nakatsukasa, Hiroko, Ito, Minako, Kondo, Taisuke, Tateda, Kenn-ichi, Akanuma, Takashi, Koya, Ikuko, Sanosaka, Tsukasa, Kohyama, Jun, Tsukada, Yu-ichi, Takamura-Enya, Takeji, Yoshimura, Akihiko
Publicado 2017

Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential

por Lam, Matti, Sanosaka, Tsukasa, Lundin, Anders, Imaizumi, Kent, Etal, Damla, Karlsson, Fredrik H., Clausen, Maryam, Cairns, Jonathan, Hicks, Ryan, Kohyama, Jun, Kele, Malin, Okano, Hideyuki, Falk, Anna
Publicado 2019

Reduced Adult Hippocampal Neurogenesis and Cognitive Impairments following Prenatal Treatment of the Antiepileptic Drug Valproic Acid

por Juliandi, Berry, Tanemura, Kentaro, Igarashi, Katsuhide, Tominaga, Takashi, Furukawa, Yusuke, Otsuka, Maky, Moriyama, Noriko, Ikegami, Daigo, Abematsu, Masahiko, Sanosaka, Tsukasa, Tsujimura, Keita, Narita, Minoru, Kanno, Jun, Nakashima, Kinichi
Publicado 2015

CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations

por Okuno, Hironobu, Renault Mihara, Francois, Ohta, Shigeki, Fukuda, Kimiko, Kurosawa, Kenji, Akamatsu, Wado, Sanosaka, Tsukasa, Kohyama, Jun, Hayashi, Kanehiro, Nakajima, Kazunori, Takahashi, Takao, Wysocka, Joanna, Kosaki, Kenjiro, Okano, Hideyuki
Publicado 2017

Coupling of angiogenesis and odontogenesis orchestrates tooth mineralization in mice

por Matsubara, Tomoko, Iga, Takahito, Sugiura, Yuki, Kusumoto, Dai, Sanosaka, Tsukasa, Tai-Nagara, Ikue, Takeda, Norihiko, Fong, Guo-Hua, Ito, Kosei, Ema, Masatsugu, Okano, Hideyuki, Kohyama, Jun, Suematsu, Makoto, Kubota, Yoshiaki
Publicado 2022

Generation of a tyrosine hydroxylase-2A-Cre knockin non-human primate model by homology-directed-repair-biased CRISPR genome editing

por Yoshimatsu, Sho, Okahara, Junko, Yoshie, Junko, Igarashi, Yoko, Nakajima, Ryusuke, Sanosaka, Tsukasa, Qian, Emi, Sato, Tsukika, Kobayashi, Hiroya, Morimoto, Satoru, Kishi, Noriyuki, Pillis, Devin M., Malik, Punam, Noce, Toshiaki, Okano, Hideyuki
Publicado 2023

Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors

por Chai, MuhChyi, Sanosaka, Tsukasa, Okuno, Hironobu, Zhou, Zhi, Koya, Ikuko, Banno, Satoe, Andoh-Noda, Tomoko, Tabata, Yoshikuni, Shimamura, Rieko, Hayashi, Tetsutaro, Ebisawa, Masashi, Sasagawa, Yohei, Nikaido, Itoshi, Okano, Hideyuki, Kohyama, Jun
Publicado 2018

A robust culture system to generate neural progenitors with gliogenic competence from clinically relevant induced pluripotent stem cells for treatment of spinal cord injury

por Kamata, Yasuhiro, Isoda, Miho, Sanosaka, Tsukasa, Shibata, Reo, Ito, Shuhei, Okubo, Toshiki, Shinozaki, Munehisa, Inoue, Mitsuhiro, Koya, Ikuko, Shibata, Shinsuke, Shindo, Tomoko, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki, Nagoshi, Narihito, Kohyama, Jun
Publicado 2020

Non-viral Induction of Transgene-free iPSCs from Somatic Fibroblasts of Multiple Mammalian Species

por Yoshimatsu, Sho, Nakajima, Mayutaka, Iguchi, Aozora, Sanosaka, Tsukasa, Sato, Tsukika, Nakamura, Mari, Nakajima, Ryusuke, Arai, Eri, Ishikawa, Mitsuru, Imaizumi, Kent, Watanabe, Hirotaka, Okahara, Junko, Noce, Toshiaki, Takeda, Yuta, Sasaki, Erika, Behr, Rüdiger, Edamura, Kazuya, Shiozawa, Seiji, Okano, Hideyuki
Publicado 2021

Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis

por Iga, Takahito, Kobayashi, Hiroshi, Kusumoto, Dai, Sanosaka, Tsukasa, Fujita, Nobuyuki, Tai-Nagara, Ikue, Ando, Tomofumi, Takahashi, Tomoko, Matsuo, Koichi, Hozumi, Katsuto, Ito, Kosei, Ema, Masatsugu, Miyamoto, Takeshi, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki, Shibata, Shinsuke, Kohyama, Jun, Kim, Kevin K., Takubo, Keiyo, Kubota, Yoshiaki
Publicado 2023