Comparison of the Intracellular Trafficking Itinerary of CTLA-4 Orthologues

por Kaur, Satdip, Qureshi, Omar S., Sansom, David M.
Publicado 2013

Confusing signals: Recent progress in CTLA-4 biology

por Walker, Lucy S.K., Sansom, David M.
Publicado 2015

Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis

por Williams, Cayman, Kennedy, Alan, Robinson, Maximillian A., Lloyd, Christopher, Dovedi, Simon J., Sansom, David M.
Publicado 2022

Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint

por Jeffery, Louisa E., Henley, Peter, Marium, Nefisa, Filer, Andrew, Sansom, David M., Hewison, Martin, Raza, Karim
Publicado 2018

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

por Glinos, Dafni A., Soskic, Blagoje, Williams, Cayman, Kennedy, Alan, Jostins, Luke, Sansom, David M., Trynka, Gosia
Publicado 2020

1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept

por Gardner, David H., Jeffery, Louisa E., Soskic, Blagoje, Briggs, Zoe, Hou, Tie Zheng, Raza, Karim, Sansom, David M.
Publicado 2015

The CTLA‐4 immune checkpoint protein regulates PD‐L1:PD‐1 interaction via transendocytosis of its ligand CD80

por Kennedy, Alan, Robinson, Maximillian A, Hinze, Claudia, Waters, Erin, Williams, Cayman, Halliday, Neil, Dovedi, Simon, Sansom, David M
Publicado 2023

Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function

por Jeffery, Louisa E., Qureshi, Omar S., Gardner, David, Hou, Tie Z., Briggs, Zoe, Soskic, Blagoje, Baker, Jennifer, Raza, Karim, Sansom, David M.
Publicado 2015

Regulation of CTLA‐4 recycling by LRBA and Rab11

por Janman, Daniel, Hinze, Claudia, Kennedy, Alan, Halliday, Neil, Waters, Erin, Williams, Cayman, Rowshanravan, Behzad, Hou, Tie Zheng, Minogue, Shane, Qureshi, Omar S., Sansom, David M.
Publicado 2021

Low-level Hypermutation in T Cell–independent Germinal Centers Compared with High Mutation Rates Associated with T Cell–dependent Germinal Centers

por Toellner, Kai-Michael, Jenkinson, William E., Taylor, Dale R., Khan, Mahmood, Sze, Daniel M.-Y., Sansom, David M., Vinuesa, Carola G., MacLennan, Ian C.M.
Publicado 2002

CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis

por Soskic, Blagoje, Jeffery, Louisa E., Kennedy, Alan, Gardner, David H., Hou, Tie Zheng, Halliday, Neil, Williams, Cayman, Janman, Daniel, Rowshanravan, Behzad, Hirschfield, Gideon M., Sansom, David M.
Publicado 2021

Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation

por Qureshi, Omar S., Kaur, Satdip, Hou, Tie Zheng, Jeffery, Louisa E., Poulter, Natalie S., Briggs, Zoe, Kenefeck, Rupert, Willox, Anna K., Royle, Stephen J., Rappoport, Joshua Z., Sansom, David M.
Publicado 2012

CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4

por Halliday, Neil, Williams, Cayman, Kennedy, Alan, Waters, Erin, Pesenacker, Anne M., Soskic, Blagoje, Hinze, Claudia, Hou, Tie Zheng, Rowshanravan, Behzad, Janman, Daniel, Walker, Lucy S. K., Sansom, David M.
Publicado 2020

Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

por Kennedy, Alan, Waters, Erin, Rowshanravan, Behzad, Hinze, Claudia, Williams, Cayman, Janman, Daniel, Fox, Thomas A., Booth, Claire, Pesenacker, Anne M., Halliday, Neil, Soskic, Blagoje, Kaur, Satdip, Qureshi, Omar S., Morris, Emma C., Ikemizu, Shinji, Paluch, Christopher, Huo, Jiandong, Davis, Simon J., Boucrot, Emmanuel, Walker, Lucy S. K., Sansom, David M.
Publicado 2022

Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS)

por Dancer, Rachel C A, Parekh, Dhruv, Lax, Sian, D'Souza, Vijay, Zheng, Shengxing, Bassford, Chris R, Park, Daniel, Bartis, D G, Mahida, Rahul, Turner, Alice M, Sapey, Elizabeth, Wei, Wenbin, Naidu, Babu, Stewart, Paul M, Fraser, William D, Christopher, Kenneth B, Cooper, Mark S, Gao, Fang, Sansom, David M, Martineau, Adrian R, Perkins, Gavin D, Thickett, David R
Publicado 2015

Thymus transplantation for complete DiGeorge syndrome: European experience

por Davies, E. Graham, Cheung, Melissa, Gilmour, Kimberly, Maimaris, Jesmeen, Curry, Joe, Furmanski, Anna, Sebire, Neil, Halliday, Neil, Mengrelis, Konstantinos, Adams, Stuart, Bernatoniene, Jolanta, Bremner, Ronald, Browning, Michael, Devlin, Blythe, Erichsen, Hans Christian, Gaspar, H. Bobby, Hutchison, Lizzie, Ip, Winnie, Ifversen, Marianne, Leahy, T. Ronan, McCarthy, Elizabeth, Moshous, Despina, Neuling, Kim, Pac, Malgorzata, Papadopol, Alina, Parsley, Kathryn L., Poliani, Luigi, Ricciardelli, Ida, Sansom, David M., Voor, Tiia, Worth, Austen, Crompton, Tessa, Markert, M. Louise, Thrasher, Adrian J.
Publicado 2017

Autosomal-dominant immune dysregulation syndrome in humans with CTLA4 mutations

por Schubert, Desirée, Bode, Claudia, Kenefeck, Rupert, Hou, Tie Zheng, Wing, James B., Kennedy, Alan, Bulashevska, Alla, Petersen, Britt-Sabina, Schäffer, Alejandro A., Grüning, Björn A., Unger, Susanne, Frede, Natalie, Baumann, Ulrich, Witte, Torsten, Schmidt, Reinhold E., Dueckers, Gregor, Niehues, Tim, Seneviratne, Suranjith, Kanariou, Maria, Speckmann, Carsten, Ehl, Stephan, Rensing-Ehl, Anne, Warnatz, Klaus, Rakhmanov, Mirzokhid, Thimme, Robert, Hasselblatt, Peter, Emmerich, Florian, Cathomen, Toni, Backofen, Rolf, Fisch, Paul, Seidl, Maximilian, May, Annette, Schmitt-Graeff, Annette, Ikemizu, Shinji, Salzer, Ulrich, Franke, Andre, Sakaguchi, Shimon, Walker, Lucy S.K., Sansom, David M., Grimbacher, Bodo
Publicado 2014

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

por Serwas, Nina K., Hoeger, Birgit, Ardy, Rico C., Stulz, Sigrun V., Sui, Zhenhua, Memaran, Nima, Meeths, Marie, Krolo, Ana, Yüce Petronczki, Özlem, Pfajfer, Laurène, Hou, Tie Z., Halliday, Neil, Santos-Valente, Elisangela, Kalinichenko, Artem, Kennedy, Alan, Mace, Emily M., Mukherjee, Malini, Tesi, Bianca, Schrempf, Anna, Pickl, Winfried F., Loizou, Joanna I., Kain, Renate, Bidmon-Fliegenschnee, Bettina, Schickel, Jean-Nicolas, Glauzy, Salomé, Huemer, Jakob, Garncarz, Wojciech, Salzer, Elisabeth, Pierides, Iro, Bilic, Ivan, Thiel, Jens, Priftakis, Peter, Banerjee, Pinaki P., Förster-Waldl, Elisabeth, Medgyesi, David, Huber, Wolf-Dietrich, Orange, Jordan S., Meffre, Eric, Sansom, David M., Bryceson, Yenan T., Altman, Amnon, Boztug, Kaan
Publicado 2019

Publisher Correction: Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

por Serwas, Nina K., Hoeger, Birgit, Ardy, Rico C., Stulz, Sigrun V., Sui, Zhenhua, Memaran, Nima, Meeths, Marie, Krolo, Ana, Petronczki, Özlem Yüce, Pfajfer, Laurène, Hou, Tie Z., Halliday, Neil, Santos-Valente, Elisangela, Kalinichenko, Artem, Kennedy, Alan, Mace, Emily M., Mukherjee, Malini, Tesi, Bianca, Schrempf, Anna, Pickl, Winfried F., Loizou, Joanna I., Kain, Renate, Bidmon-Fliegenschnee, Bettina, Schickel, Jean-Nicolas, Glauzy, Salomé, Huemer, Jakob, Garncarz, Wojciech, Salzer, Elisabeth, Pierides, Iro, Bilic, Ivan, Thiel, Jens, Priftakis, Peter, Banerjee, Pinaki P., Förster-Waldl, Elisabeth, Medgyesi, David, Huber, Wolf-Dietrich, Orange, Jordan S., Meffre, Eric, Sansom, David M., Bryceson, Yenan T., Altman, Amnon, Boztug, Kaan
Publicado 2019

Whole genome sequencing of a sporadic primary immunodeficiency cohort

por Thaventhiran, James E. D., Allen, Hana Lango, Burren, Oliver S., Rae, William, Greene, Daniel, Staples, Emily, Zhang, Zinan, Farmery, James H. R., Simeoni, Ilenia, Rivers, Elizabeth, Maimaris, Jesmeen, Penkett, Christopher J, Stephens, Jonathan, Deevi, Sri V.V., Sanchis-Juan, Alba, Gleadall, Nicholas S, Thomas, Moira J., Sargur, Ravishankar B., Gordins, Pavels, Baxendale, Helen E., Brown, Matthew, Tuijnenburg, Paul, Worth, Austen, Hanson, Steven, Linger, Rachel, Buckland, Matthew S., Rayner-Matthews, Paula J., Gilmour, Kimberly C., Samarghitean, Crina, Seneviratne, Suranjith L., Sansom, David M., Lynch, Andy G., Megy, Karyn, Ellinghaus, Eva, Ellinghaus, David, Jorgensen, Silje F., Karlsen, Tom H, Stirrups, Kathleen E., Cutler, Antony J., Kumararatne, Dinakantha S., Chandra, Anita, Edgar, J. David M., Herwadkar, Archana, Cooper, Nichola, Grigoriadou, Sofia, Huissoon, Aarnoud, Goddard, Sarah, Jolles, Stephen, Schuetz, Catharina, Boschann, Felix, Lyons, Paul A., Hurles, Matthew E., Savic, Sinisa, Burns, Siobhan O., Kuijpers, Taco W., Turro, Ernest, Ouwehand, Willem H., Thrasher, Adrian J., Smith, Kenneth G. C.
Publicado 2020