Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses

por Santarelli, Roberta, Granato, Marisa, Faggioni, Alberto, Cirone, Mara
Publicado 2015

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future

por Granato, Marisa, Santarelli, Roberta, Gonnella, Roberta, Farina, Antonella, Trivedi, Pankaj, Faggioni, Alberto, Cirone, Mara
Publicado 2015

3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]...

por Santarelli, Roberta, Pompili, Chiara, Gilardini Montani, Maria Saveria, Evangelista, Lorenzo, Gonnella, Roberta, Cirone, Mara
Publicado 2022

HSPs/STAT3 Interplay Sustains DDR and Promotes Cytokine Release by Primary Effusion Lymphoma Cells

por Gonnella, Roberta, Arena, Andrea, Zarrella, Roberta, Gilardini Montani, Maria Saveria, Santarelli, Roberta, Cirone, Mara
Publicado 2023

Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1

por Romeo, Maria Anele, Gilardini Montani, Maria Saveria, Santarelli, Roberta, Benedetti, Rossella, Arena, Andrea, Cirone, Mara
Publicado 2023

Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line

por Gonnella, Roberta, Santarelli, Roberta, Farina, Antonella, Granato, Marisa, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Publicado 2013

Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death

por Granato, Marisa, Gilardini Montani, Maria Saveria, Santarelli, Roberta, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Publicado 2017

IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation

por Gonnella, Roberta, Gilardini Montani, Maria Saveria, Guttieri, Luisa, Romeo, Maria Anele, Santarelli, Roberta, Cirone, Mara
Publicado 2021

Mechanisms of Sensitivity and Resistance of Primary Effusion Lymphoma to Dimethyl Fumarate (DMF)

por Gonnella, Roberta, Zarrella, Roberta, Santarelli, Roberta, Germano, Concetta Anna, Gilardini Montani, Maria Saveria, Cirone, Mara
Publicado 2022

STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway

por Romeo, Maria Anele, Gilardini Montani, Maria Saveria, Benedetti, Rossella, Santarelli, Roberta, D'Orazi, Gabriella, Cirone, Mara
Publicado 2020

The activation of KSHV lytic cycle blocks autophagy in PEL cells

por Granato, Marisa, Santarelli, Roberta, Filardi, Mariarosaria, Gonnella, Roberta, Farina, Antonella, Torrisi, Maria Rosaria, Faggioni, Alberto, Cirone, Mara
Publicado 2015

Viral Infection and Autophagy Dysregulation: The Case of HHV-6, EBV and KSHV

por Romeo, Maria Anele, Santarelli, Roberta, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Benedetti, Rossella, Faggioni, Alberto, Cirone, Mara
Publicado 2020

Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation

por Gonnella, Roberta, Guttieri, Luisa, Gilardini Montani, Maria Saveria, Santarelli, Roberta, Bassetti, Erica, D’Orazi, Gabriella, Cirone, Mara
Publicado 2022

HHV-8 reduces dendritic cell migration through down-regulation of cell-surface CCR6 and CCR7 and cytoskeleton reorganization

por Cirone, Mara, Conte, Valeria, Farina, Antonella, Valia, Sandro, Trivedi, Pankaj, Granato, Marisa, Santarelli, Roberta, Frati, Luigi, Faggioni, Alberto
Publicado 2012

Targeting COX-2/PGE(2) Pathway in HIPK2 Knockdown Cancer Cells: Impact on Dendritic Cell Maturation

por Garufi, Alessia, Pistritto, Giuseppa, Ceci, Claudia, Di Renzo, Livia, Santarelli, Roberta, Faggioni, Alberto, Cirone, Mara, D’Orazi, Gabriella
Publicado 2012

Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross‐talk with p53 to activate p21

por Santarelli, Roberta, Pompili, Chiara, Gilardini Montani, Maria Saveria, Romeo, Maria Anele, Gonnella, Roberta, D'Orazi, Gabriella, Cirone, Mara
Publicado 2021

Role of UPR Sensor Activation in Cell Death–Survival Decision of Colon Cancer Cells Stressed by DPE Treatment

por Benedetti, Rossella, Gilardini Montani, Maria Saveria, Romeo, Maria Anele, Arena, Andrea, Santarelli, Roberta, D’Orazi, Gabriella, Cirone, Mara
Publicado 2021

STAT3 activation by KSHV correlates with IL-10, IL-6 and IL-23 release and an autophagic block in dendritic cells

por Santarelli, Roberta, Gonnella, Roberta, Di Giovenale, Giulia, Cuomo, Laura, Capobianchi, Angela, Granato, Marisa, Gentile, Giuseppe, Faggioni, Alberto, Cirone, Mara
Publicado 2014

Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas

por Benedetti, Rossella, Arena, Andrea, Romeo, Maria Anele, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Santarelli, Roberta, Trivedi, Pankaj, Cirone, Mara
Publicado 2022

NRF2 and STAT3: friends or foes in carcinogenesis?

por Arena, Andrea, Romeo, Maria Anele, Benedetti, Rossella, Gilardini Montani, Maria Saveria, Santarelli, Roberta, Gonnella, Roberta, D’Orazi, Gabriella, Cirone, Mara
Publicado 2023