Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes

por Biddau, Marco, Santha Kumar, T.R., Henrich, Philipp, Laine, Larissa M., Blackburn, Gavin J., Chokkathukalam, Achuthanunni, Li, Tao, Lee Sim, Kim, King, Lewis, Hoffman, Stephen L., Barrett, Michael P., Coombs, Graham H., McFadden, Geoffrey I., Fidock, David A., Müller, Sylke, Sheiner, Lilach
Publicado 2021

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

por LaMonte, Gregory M., Rocamora, Frances, Marapana, Danushka S., Gnädig, Nina F., Ottilie, Sabine, Luth, Madeline R., Worgall, Tilla S., Goldgof, Gregory M., Mohunlal, Roxanne, Santha Kumar, T. R., Thompson, Jennifer K., Vigil, Edgar, Yang, Jennifer, Hutson, Dylan, Johnson, Trevor, Huang, Jianbo, Williams, Roy M., Zou, Bing Yu, Cheung, Andrea L., Kumar, Prianka, Egan, Timothy J., Lee, Marcus C. S., Siegel, Dionicio, Cowman, Alan F., Fidock, David A., Winzeler, Elizabeth A.
Publicado 2020