PIM kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1

por Mung, Kwan Long, Eccleshall, William B., Santio, Niina M., Rivero-Müller, Adolfo, Koskinen, Päivi J.
Publicado 2021

PIM-Related Kinases Selectively Regulate Olfactory Sensations in Caenorhabditis elegans

por Kalichamy, Karunambigai S., Ikkala, Kaisa, Pörsti, Jonna, Santio, Niina M., Tuomaala, Joel, Jha, Sweta, Holmberg, Carina I., Koskinen, Päivi J.
Publicado 2019

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

por Santio, Niina M., Eerola, Sini K., Paatero, Ilkka, Yli-Kauhaluoma, Jari, Anizon, Fabrice, Moreau, Pascale, Tuomela, Johanna, Härkönen, Pirkko, Koskinen, Päivi J.
Publicado 2015

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

por Santio, Niina M, Vahakoski, Riitta L, Rainio, Eeva-Marja, Sandholm, Jouko A, Virtanen, Sanna S, Prudhomme, Michelle, Anizon, Fabrice, Moreau, Pascale, Koskinen, Päivi J
Publicado 2010

Tricyclic Benzo[cd]azulenes Selectively Inhibit Activities of Pim Kinases and Restrict Growth of Epstein-Barr Virus-Transformed Cells

por Kiriazis, Alexandros, Vahakoski, Riitta L., Santio, Niina M., Arnaudova, Ralica, Eerola, Sini K., Rainio, Eeva-Marja, Aumüller, Ingo B., Yli-Kauhaluoma, Jari, Koskinen, Päivi J.
Publicado 2013

Correction: Tricyclic Benzo[cd]azulenes Selectively Inhibit Activities of Pim Kinases and Restrict Growth of Epstein-Barr Virus-Transformed Cells

por Kiriazis, Alexandros, Vahakoski, Riitta L., Santio, Niina M., Arnaudova, Ralica, Eerola, Sini K., Rainio, Eeva-Marja, Aumüller, Ingo B., Yli-Kauhaluoma, Jari, Koskinen, Päivi J.
Publicado 2013

PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins

por Santio, Niina M., Vainio, Veera, Hoikkala, Tuuli, Mung, Kwan Long, Lång, Mirka, Vahakoski, Riitta, Zdrojewska, Justyna, Coffey, Eleanor T., Kremneva, Elena, Rainio, Eeva-Marja, Koskinen, Päivi J.
Publicado 2020

Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

por Santio, Niina M., Landor, Sebastian K.-J., Vahtera, Laura, Ylä-Pelto, Jani, Paloniemi, Elina, Imanishi, Susumu Y., Corthals, Garry, Varjosalo, Markku, Manoharan, Ganesh Babu, Uri, Asko, Lendahl, Urban, Sahlgren, Cecilia, Koskinen, Päivi J.
Publicado 2016

Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion

por Eerola, Sini K., Santio, Niina M., Rinne, Sanni, Kouvonen, Petri, Corthals, Garry L., Scaravilli, Mauro, Scala, Giovanni, Serra, Angela, Greco, Dario, Ruusuvuori, Pekka, Latonen, Leena, Rainio, Eeva-Marja, Visakorpi, Tapio, Koskinen, Päivi J.
Publicado 2019

PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion

por Landor, Sebastian K.J., Santio, Niina M., Eccleshall, William B., Paramonov, Valeriy M., Gagliani, Ellen K., Hall, Daniel, Jin, Shao-Bo, Dahlström, Käthe M., Salminen, Tiina A., Rivero-Müller, Adolfo, Lendahl, Urban, Kovall, Rhett A., Koskinen, Päivi J., Sahlgren, Cecilia
Publicado 2021