Redox signaling in cardiac myocytes

por Santos, Celio X.C., Anilkumar, Narayana, Zhang, Min, Brewer, Alison C., Shah, Ajay M.
Publicado 2011

The regulation of cardiac intermediary metabolism by NADPH oxidases

por Nabeebaccus, Adam A, Reumiller, Christina M, Shen, Jie, Zoccarato, Anna, Santos, Celio X C, Shah, Ajay M
Publicado 2022

NADPH Oxidase 2 Mediates Myocardial Oxygen Wasting in Obesity

por Hafstad, Anne D., Hansen, Synne S., Lund, Jim, Santos, Celio X. C., Boardman, Neoma T., Shah, Ajay M., Aasum, Ellen
Publicado 2020

Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2

por A Nabeebaccus, Adam, Verma, Sharwari, Zoccarato, Anna, Emanuelli, Giulia, Santos, Celio XC., Streckfuss-Bömeke, Katrin, Shah, Ajay M.
Publicado 2021

Blood Pressure–Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase

por Prysyazhna, Oleksandra, Wolhuter, Kathryn, Switzer, Christopher, Santos, Celio, Yang, Xiaoping, Lynham, Steven, Shah, Ajay M., Eaton, Philip, Burgoyne, Joseph R.
Publicado 2019

Protein Disulfide Isomerase and Host-Pathogen Interaction

por Stolf, Beatriz S., Smyrnias, Ioannis, Lopes, Lucia R., Vendramin, Alcione, Goto, Hiro, Laurindo, Francisco R. M., Shah, Ajay M., Santos, Celio X. C.
Publicado 2011

Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling

por Mistry, Rajesh K., Murray, Thomas V. A., Prysyazhna, Oleksandra, Martin, Daniel, Burgoyne, Joseph R., Santos, Celio, Eaton, Philip, Shah, Ajay M., Brewer, Alison C.
Publicado 2016

Cell-specific effects of Nox2 on the acute and chronic response to myocardial infarction

por Sirker, Alexander, Murdoch, Colin E., Protti, Andrea, Sawyer, Greta J., Santos, Celio X.C., Martin, Daniel, Zhang, Xiaohong, Brewer, Alison C., Zhang, Min, Shah, Ajay M.
Publicado 2016

Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells

por Harrison, Craig B., Trevelin, Silvia Cellone, Richards, Daniel A., Santos, Celio X.C., Sawyer, Greta, Markovinovic, Andrea, Zhang, Xiaohong, Zhang, Min, Brewer, Alison C., Yin, Xiaoke, Mayr, Manuel, Shah, Ajay M.
Publicado 2020

Contractile Function During Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

por Zhang, Min, Prosser, Benjamin L., Bamboye, Moradeke A., Gondim, Antonio N.S., Santos, Celio X., Martin, Daniel, Ghigo, Alessandra, Perino, Alessia, Brewer, Alison C., Ward, Christopher W., Hirsch, Emilio, Lederer, W. Jonathan, Shah, Ajay M.
Publicado 2015

Nox4 regulates InsP(3) receptor‐dependent Ca(2+) release into mitochondria to promote cell survival

por Beretta, Matteo, Santos, Celio XC, Molenaar, Chris, Hafstad, Anne D, Miller, Chris CJ, Revazian, Aram, Betteridge, Kai, Schröder, Katrin, Streckfuß‐Bömeke, Katrin, Doroshow, James H, Fleck, Roland A, Su, Tsung‐Ping, Belousov, Vsevolod V, Parsons, Maddy, Shah, Ajay M
Publicado 2020

Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction

por Sukumar, Piruthivi, Viswambharan, Hema, Imrie, Helen, Cubbon, Richard M., Yuldasheva, Nadira, Gage, Matthew, Galloway, Stacey, Skromna, Anna, Kandavelu, Parkavi, Santos, Celio X., Gatenby, V. Kate, Smith, Jessica, Beech, David J., Wheatcroft, Stephen B., Channon, Keith M., Shah, Ajay M., Kearney, Mark T.
Publicado 2013

Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure

por Sag, Can Martin, Schnelle, Moritz, Zhang, Juqian, Murdoch, Colin E., Kossmann, Sabine, Protti, Andrea, Santos, Celio X.C., Sawyer, Greta, Zhang, Xiaohong, Mongue-Din, Heloise, Richards, Daniel A., Brewer, Alison C., Prysyazhna, Oleksandra, Maier, Lars S., Wenzel, Philip, Eaton, Philip J., Shah, Ajay M.
Publicado 2017

Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

por Nabeebaccus, Adam A., Zoccarato, Anna, Hafstad, Anne D., Santos, Celio X.C., Aasum, Ellen, Brewer, Alison C., Zhang, Min, Beretta, Matteo, Yin, Xiaoke, West, James A., Schröder, Katrin, Griffin, Julian L., Eykyn, Thomas R., Abel, E. Dale, Mayr, Manuel, Shah, Ajay M.
Publicado 2017

Endothelial Nox2 Limits Systemic Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4

por Trevelin, Silvia Cellone, Sag, Can Martin, Zhang, Min, Alves-Filho, José Carlos, Cunha, Thiago Mattar, dos Santos, Célio Xavier, Sawyer, Greta, Murray, Thomas, Brewer, Alison, Laurindo, Francisco Rafael Martins, Protti, Andrea, Lopes, Lucia Rossetti, Ivetic, Aleksandar, Cunha, Fernando Queiroz, Shah, Ajay M.
Publicado 2021

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients

por Haupt, Luis Peter, Rebs, Sabine, Maurer, Wiebke, Hübscher, Daniela, Tiburcy, Malte, Pabel, Steffen, Maus, Andreas, Köhne, Steffen, Tappu, Rewati, Haas, Jan, Li, Yun, Sasse, Andre, Santos, Celio C. X., Dressel, Ralf, Wojnowski, Leszek, Bunt, Gertrude, Möbius, Wiebke, Shah, Ajay M., Meder, Benjamin, Wollnik, Bernd, Sossalla, Samuel, Hasenfuss, Gerd, Streckfuss-Bömeke, Katrin
Publicado 2022

Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

por Romeo, Sara G., Secco, Ilaria, Schneider, Edoardo, Reumiller, Christina M., Santos, Celio X. C., Zoccarato, Anna, Musale, Vishal, Pooni, Aman, Yin, Xiaoke, Theofilatos, Konstantinos, Trevelin, Silvia Cellone, Zeng, Lingfang, Mann, Giovanni E., Pathak, Varun, Harkin, Kevin, Stitt, Alan W., Medina, Reinhold J., Margariti, Andriana, Mayr, Manuel, Shah, Ajay M., Giacca, Mauro, Zampetaki, Anna
Publicado 2023

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α‐mediated stress signaling

por Santos, Celio XC, Hafstad, Anne D, Beretta, Matteo, Zhang, Min, Molenaar, Chris, Kopec, Jola, Fotinou, Dina, Murray, Thomas V, Cobb, Andrew M, Martin, Daniel, Zeh Silva, Maira, Anilkumar, Narayana, Schröder, Katrin, Shanahan, Catherine M, Brewer, Alison C, Brandes, Ralf P, Blanc, Eric, Parsons, Maddy, Belousov, Vsevelod, Cammack, Richard, Hider, Robert C, Steiner, Roberto A, Shah, Ajay M
Publicado 2016

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

por Trevelin, Silvia Cellone, dos Santos, Célio Xavier, Ferreira, Raphael Gomes, de Sá Lima, Larissa, Silva, Rangel Leal, Scavone, Cristoforo, Curi, Rui, Alves-Filho, José Carlos, Cunha, Thiago Mattar, Roxo-Júnior, Pérsio, Cervi, Maria-Célia, Laurindo, Francisco Rafael Martins, Hothersall, John Stephen, Cobb, Andrew M., Zhang, Min, Ivetic, Aleksandar, Shah, Ajay M., Lopes, Lucia Rossetti, Cunha, Fernando Queiroz
Publicado 2016

EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

por Randzavola, Lyra O, Mortimer, Paige M, Garside, Emma, Dufficy, Elizabeth R, Schejtman, Andrea, Roumelioti, Georgia, Yu, Lu, Pardo, Mercedes, Spirohn, Kerstin, Tolley, Charlotte, Brandt, Cordelia, Harcourt, Katherine, Nichols, Esme, Nahorski, Mike, Woods, Geoff, Williamson, James C, Suresh, Shreehari, Sowerby, John M, Matsumoto, Misaki, Santos, Celio XC, Kiar, Cher Shen, Mukhopadhyay, Subhankar, Rae, William M, Dougan, Gordon J, Grainger, John, Lehner, Paul J, Calderwood, Michael A, Choudhary, Jyoti, Clare, Simon, Speak, Anneliese, Santilli, Giorgia, Bateman, Alex, Smith, Kenneth GC, Magnani, Francesca, Thomas, David C
Publicado 2022