Robust IL-2-dependent antitumor immunotherapy requires targeting the high-affinity IL-2R on tumor-specific CD8(+) T cells

por LaPorte, Kathryn M, Hernandez, Rosmely, Santos Savio, Alicia, Malek, Thomas R
Publicado 2023

High-dose IL-2/CD25 fusion protein amplifies vaccine-induced CD4(+) and CD8(+) neoantigen-specific T cells to promote antitumor immunity

por Hernandez, Rosmely, LaPorte, Kathryn M, Hsiung, Sunnie, Santos Savio, Alicia, Malek, Thomas R
Publicado 2021

Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15

por Rodríguez-Álvarez, Yunier, Batista-Roche, Lino Gerardo, Llopiz-Arzuaga, Alexey, Puente-Pérez, Pedro, Martínez-Castillo, Rafael, Castro-Velazco, Jorge, Santos-Savio, Alicia
Publicado 2021

Differential expression of pro-inflammatory cytokines IL-15Ralpha, IL-15, IL-6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients

por Santos Savio, Alicia, Machado Diaz, Ana Cecilia, Chico Capote, Araceli, Miranda Navarro, Jamilet, Rodríguez Alvarez, Yunier, Bringas Pérez, Ricardo, Estévez del Toro, Miguel, Guillen Nieto, Gerardo E
Publicado 2015

Proinflammatory Soluble Interleukin-15 Receptor Alpha Is Increased in Rheumatoid Arthritis

por Machado Diaz, Ana Cecilia, Chico Capote, Araceli, Arrieta Aguero, Celia Aurora, Rodríguez Alvarez, Yunier, García del Barco Herrera, Diana, Estévez del Toro, Miguel, Guillen Nieto, Gerardo E., Santos Savio, Alicia
Publicado 2012

Active immunization with human interleukin-15 induces neutralizing antibodies in non-human primates

por Rodríguez-Álvarez, Yunier, Morera-Díaz, Yanelys, Gerónimo-Pérez, Haydee, Castro-Velazco, Jorge, Martínez-Castillo, Rafael, Puente-Pérez, Pedro, Besada-Pérez, Vladimir, Hardy-Rando, Eugenio, Chico-Capote, Araceli, Martínez-Cordovez, Klaudia, Santos-Savio, Alicia
Publicado 2016