Structural inspection and protein motions modelling of a fungal glycoside hydrolase family 18 chitinase by crystallography depicts a dynamic enzymatic mechanism

por Jiménez-Ortega, Elena, Kidibule, Peter Elias, Fernández-Lobato, María, Sanz-Aparicio, Julia
Publicado 2021

Structure–Function Insights into the Fungal Endo-Chitinase Chit33 Depict its Mechanism on Chitinous Material

por Jiménez-Ortega, Elena, Kidibule, Peter Elias, Fernández-Lobato, María, Sanz-Aparicio, Julia
Publicado 2022

Phylogenetic, functional and structural characterization of a GH10 xylanase active at extreme conditions of temperature and alkalinity

por Talens-Perales, David, Jiménez-Ortega, Elena, Sánchez-Torres, Paloma, Sanz-Aparicio, Julia, Polaina, Julio
Publicado 2021

The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function

por Franco-Echevarría, Elsa, Sanz-Aparicio, Julia, Brearley, Charles A., González-Rubio, Juana M., González, Beatriz
Publicado 2017

Insights into the Structure of the Highly Glycosylated Ffase from Rhodotorula dairenensis Enhance Its Biotechnological Potential

por Jiménez-Ortega, Elena, Narmontaite, Egle, González-Pérez, Beatriz, Plou, Francisco J., Fernández-Lobato, María, Sanz-Aparicio, Julia
Publicado 2022

Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase

por Cea-Rama, Isabel, Coscolín, Cristina, Katsonis, Panagiotis, Bargiela, Rafael, Golyshin, Peter N., Lichtarge, Olivier, Ferrer, Manuel, Sanz-Aparicio, Julia
Publicado 2021

Increased Thermostability of an Engineered Flavin-Containing Monooxygenase to Remediate Trimethylamine in Fish Protein Hydrolysates

por Goris, Marianne, Cea-Rama, Isabel, Puntervoll, Pål, Ree, Rasmus, Almendral, David, Sanz-Aparicio, Julia, Ferrer, Manuel, Bjerga, Gro Elin Kjæreng
Publicado 2023

Deciphering the molecular specificity of phenolic compounds as inhibitors or glycosyl acceptors of β-fructofuranosidase from Xanthophyllomyces dendrorhous

por Ramirez-Escudero, Mercedes, Miguez, Noa, Gimeno-Perez, Maria, Ballesteros, Antonio O., Fernandez-Lobato, Maria, Plou, Francisco J., Sanz-Aparicio, Julia
Publicado 2019

The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome

por Distaso, Marco, Cea-Rama, Isabel, Coscolín, Cristina, Chernikova, Tatyana N., Tran, Hai, Ferrer, Manuel, Sanz-Aparicio, Julia, Golyshin, Peter N.
Publicado 2023

Crystal structure and functional insights into uracil-DNA glycosylase inhibition by phage ϕ29 DNA mimic protein p56

por Baños-Sanz, José Ignacio, Mojardín, Laura, Sanz-Aparicio, Julia, Lázaro, José M., Villar, Laurentino, Serrano-Heras, Gemma, González, Beatriz, Salas, Margarita
Publicado 2013

Crystal structure of a family VIII β‐lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope

por Cea‐Rama, Isabel, Coscolín, Cristina, Gonzalez‐Alfonso, Jose L., Raj, Jog, Vasiljević, Marko, Plou, Francisco J., Ferrer, Manuel, Sanz‐Aparicio, Julia
Publicado 2022

Structural and Functional Characterization of a Ruminal β-Glycosidase Defines a Novel Subfamily of Glycoside Hydrolase Family 3 with Permuted Domain Topology

por Ramírez-Escudero, Mercedes, del Pozo, Mercedes V., Marín-Navarro, Julia, González, Beatriz, Golyshin, Peter N., Polaina, Julio, Ferrer, Manuel, Sanz-Aparicio, Julia
Publicado 2016

New insights into the molecular mechanism behind mannitol and erythritol fructosylation by β-fructofuranosidase from Schwanniomyces occidentalis

por Rodrigo-Frutos, David, Jiménez-Ortega, Elena, Piedrabuena, David, Ramírez-Escudero, Mercedes, Míguez, Noa, Plou, Francisco J., Sanz-Aparicio, Julia, Fernández-Lobato, María
Publicado 2021

NADP(+) Binding to the Regulatory Subunit of Methionine Adenosyltransferase II Increases Intersubunit Binding Affinity in the Hetero-Trimer

por González, Beatriz, Garrido, Francisco, Ortega, Rebeca, Martínez-Júlvez, Marta, Revilla-Guarinos, Ainhoa, Pérez-Pertejo, Yolanda, Velázquez-Campoy, Adrián, Sanz-Aparicio, Julia, Pajares, María A.
Publicado 2012

Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping

por Márquez-Moñino, María Ángeles, Ortega-García, Raquel, Shipton, Megan L., Franco-Echevarría, Elsa, Riley, Andrew M., Sanz-Aparicio, Julia, Potter, Barry V. L., González, Beatriz
Publicado 2021

Use of chitin and chitosan to produce new chitooligosaccharides by chitinase Chit42: enzymatic activity and structural basis of protein specificity

por Kidibule, Peter Elias, Santos-Moriano, Paloma, Jiménez-Ortega, Elena, Ramírez-Escudero, Mercedes, Limón, M. Carmen, Remacha, Miguel, Plou, Francisco José, Sanz-Aparicio, Julia, Fernández-Lobato, María
Publicado 2018

The bone-degrading enzyme machinery: From multi-component understanding to the treatment of residues from the meat industry

por Fernandez-Lopez, Laura, Sanchez-Carrillo, Sergio, García-Moyano, Antonio, Borchert, Erik, Almendral, David, Alonso, Sandra, Cea-Rama, Isabel, Miguez, Noa, Larsen, Øivind, Werner, Johannes, Makarova, Kira S., Plou, Francisco J., Dahlgren, Thomas G., Sanz-Aparicio, Julia, Hentschel, Ute, Bjerga, Gro Elin Kjæreng, Ferrer, Manuel
Publicado 2021