Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and Function

por Väre, Ville Y. P., Eruysal, Emily R., Narendran, Amithi, Sarachan, Kathryn L., Agris, Paul F.
Publicado 2017

Solution structure of the core SMN–Gemin2 complex

por Sarachan, Kathryn L., Valentine, Kathleen G., Gupta, Kushol, Moorman, Veronica R., Gledhill, John M., Bernens, Matthew, Tommos, Cecilia, Wand, A. Joshua, Van Duyne, Gregory D.
Publicado 2012

Specificity in the biosynthesis of the universal tRNA nucleoside N(6)-threonylcarbamoyl adenosine (t(6)A)—TsaD is the gatekeeper

por Swinehart, William, Deutsch, Christopher, Sarachan, Kathryn L., Luthra, Amit, Bacusmo, Jo Marie, de Crécy-Lagard, Valérie, Swairjo, Manal A., Agris, Paul F., Iwata-Reuyl, Dirk
Publicado 2020

Silencing of the tRNA Modification Enzyme Cdkal1 Effects Functional Insulin Synthesis in NIT-1 Cells: tRNA(Lys3) Lacking ms(2)- (ms(2)t(6)A(37)) is Unable to Establish Sufficient A...

por Narendran, Amithi, Vangaveti, Sweta, Ranganathan, Srivathsan V., Eruysal, Emily, Craft, Miranda, Alrifai, Omar, Chua, Fu Yee, Sarachan, Kathryn, Litwa, Breann, Ramachandran, Sheetal, Agris, Paul F.
Publicado 2021

Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer

por Gupta, Kushol, Wen, Ying, Ninan, Nisha S, Raimer, Amanda C, Sharp, Robert, Spring, Ashlyn M, Sarachan, Kathryn L, Johnson, Meghan C, Van Duyne, Gregory D, Matera, A Gregory
Publicado 2021