Time-lapse 3-D measurements of a glucose biosensor in multicellular spheroids by light sheet fluorescence microscopy in commercial 96-well plates

por Maioli, Vincent, Chennell, George, Sparks, Hugh, Lana, Tobia, Kumar, Sunil, Carling, David, Sardini, Alessandro, Dunsby, Chris
Publicado 2016

Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM

por Chennell, George, Willows, Robin J. W., Warren, Sean C., Carling, David, French, Paul M. W., Dunsby, Chris, Sardini, Alessandro
Publicado 2016

Fluorescence Lifetime Readouts of Troponin-C-Based Calcium FRET Sensors: A Quantitative Comparison of CFP and mTFP1 as Donor Fluorophores

por Laine, Romain, Stuckey, Daniel W., Manning, Hugh, Warren, Sean C., Kennedy, Gordon, Carling, David, Dunsby, Chris, Sardini, Alessandro, French, Paul M. W.
Publicado 2012

Drug-induced loss of imprinting revealed using bioluminescent reporters of Cdkn1c

por Dimond, Andrew, Van de Pette, Mathew, Taylor-Bateman, Victoria, Brown, Karen, Sardini, Alessandro, Whilding, Chad, Feytout, Amelie, Prinjha, Rab K., Merkenschlager, Matthias, Fisher, Amanda G.
Publicado 2023

Type I interferons affect the metabolic fitness of CD8(+) T cells from patients with systemic lupus erythematosus

por Buang, Norzawani, Tapeng, Lunnathaya, Gray, Victor, Sardini, Alessandro, Whilding, Chad, Lightstone, Liz, Cairns, Thomas D., Pickering, Matthew C., Behmoaras, Jacques, Ling, Guang Sheng, Botto, Marina
Publicado 2021

In vivo fluorescence lifetime tomography of a FRET probe expressed in mouse

por McGinty, James, Stuckey, Daniel W., Soloviev, Vadim Y., Laine, Romain, Wylezinska-Arridge, Marzena, Wells, Dominic J., Arridge, Simon R., French, Paul M. W., Hajnal, Joseph V., Sardini, Alessandro
Publicado 2011

Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition

por Gleneadie, Hannah J., Fernandez-Ruiz, Beatriz, Sardini, Alessandro, Van de Pette, Mathew, Dimond, Andrew, Prinjha, Rab K., McGinty, James, French, Paul M. W., Bagci, Hakan, Merkenschlager, Matthias, Fisher, Amanda G.
Publicado 2023

Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease

por Jobbins, Andrew M, Haberman, Nejc, Artigas, Natalia, Amourda, Christopher, Paterson, Helen A B, Yu, Sijia, Blackford, Samuel J I, Montoya, Alex, Dore, Marian, Wang, Yi-Fang, Sardini, Alessandro, Cebola, Inês, Zuber, Johannes, Rashid, Sheikh Tamir, Lenhard, Boris, Vernia, Santiago
Publicado 2022

Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States

por Viskaitis, Paulius, Irvine, Elaine E., Smith, Mark A., Choudhury, Agharul I., Alvarez-Curto, Elisa, Glegola, Justyna A., Hardy, Darran G., Pedroni, Silvia M.A., Paiva Pessoa, Maria R., Fernando, Anushka B.P., Katsouri, Loukia, Sardini, Alessandro, Ungless, Mark A., Milligan, Graeme, Withers, Dominic J.
Publicado 2017

Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss

por Hope, David C.D., Hinds, Charlotte E., Lopes, Tatiana, Vincent, Matthew L., Shrewsbury, Jed V., Yu, Arthur T.C., Davies, Iona, Scott, Rebecca, Jones, Ben, Murphy, Kevin G., Minnion, James S., Sardini, Alessandro, Carling, David, Lutz, Thomas A., Bloom, Stephen R., Tan, Tricia M.M., Owen, Bryn M.
Publicado 2022

Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults

por Van de Pette, Mathew, Abbas, Allifia, Feytout, Amelie, McNamara, Gráinne, Bruno, Ludovica, To, Wilson K., Dimond, Andrew, Sardini, Alessandro, Webster, Zoe, McGinty, James, Paul, Eleanor J., Ungless, Mark A., French, Paul M.W., Withers, Dominic J., Uren, Anthony, Ferguson-Smith, Anne C., Merkenschlager, Matthias, John, Rosalind M., Fisher, Amanda G.
Publicado 2017

AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

por Pollard, Alice E., Martins, Luís, Muckett, Phillip J., Khadayate, Sanjay, Bornot, Aurélie, Clausen, Maryam, Admyre, Therese, Bjursell, Mikael, Fiadeiro, Rebeca, Wilson, Laura, Whilding, Chad, Kotiadis, Vassilios N., Duchen, Michael R., Sutton, Daniel, Penfold, Lucy, Sardini, Alessandro, Bohlooly-Y, Mohammad, Smith, David M., Read, Jon A., Snowden, Michael A., Woods, Angela, Carling, David
Publicado 2019

Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice

por Van de Pette, Mathew, Dimond, Andrew, Galvão, António M., Millership, Steven J., To, Wilson, Prodani, Chiara, McNamara, Gráinne, Bruno, Ludovica, Sardini, Alessandro, Webster, Zoe, McGinty, James, French, Paul M. W., Uren, Anthony G., Castillo-Fernandez, Juan, Watkinson, William, Ferguson-Smith, Anne C., Merkenschlager, Matthias, John, Rosalind M., Kelsey, Gavin, Fisher, Amanda G.
Publicado 2022

FLIM FRET Technology for Drug Discovery: Automated Multiwell-Plate High-Content Analysis, Multiplexed Readouts and Application in Situ**

por Kumar, Sunil, Alibhai, Dominic, Margineanu, Anca, Laine, Romain, Kennedy, Gordon, McGinty, James, Warren, Sean, Kelly, Douglas, Alexandrov, Yuriy, Munro, Ian, Talbot, Clifford, Stuckey, Daniel W, Kimberly, Christopher, Viellerobe, Bertrand, Lacombe, Francois, Lam, Eric W-F, Taylor, Harriet, Dallman, Margaret J, Stamp, Gordon, Murray, Edward J, Stuhmeier, Frank, Sardini, Alessandro, Katan, Matilda, Elson, Daniel S, Neil, Mark A A, Dunsby, Chris, French, Paul M W
Publicado 2011