Role of Telomeres and Telomerase in Cancer and Aging

por Saretzki, Gabriele
Publicado 2023

Telomerase and neurons: an unusual relationship

por Saretzki, Gabriele
Publicado 2022

Telomerase and mTOR in the brain: the mitochondria connection

por Miwa, Satomi, Saretzki, Gabriele
Publicado 2017

Telomerase in Brain: The New Kid on the Block and Its Role in Neurodegenerative Diseases

por Saretzki, Gabriele, Wan, Tengfei
Publicado 2021

CRISPR/Cas: A New Tool in the Research of Telomeres and Telomerase as Well as a Novel Form of Cancer Therapy

por Porika, Mahendar, Tippani, Radhika, Saretzki, Gabriele Christine
Publicado 2022

DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?

por Passos, João F., Saretzki, Gabriele, von Zglinicki, Thomas
Publicado 2007

Telomerase Does Not Improve DNA Repair in Mitochondria upon Stress but Increases MnSOD Protein under Serum-Free Conditions

por Martens, Alexander, Schmid, Bianca, Akintola, Olasubomi, Saretzki, Gabriele
Publicado 2019

Telomerase Activity is Downregulated Early During Human Brain Development

por Ishaq, Abbas, Hanson, Peter S., Morris, Christopher M., Saretzki, Gabriele
Publicado 2016

Dietary Restriction Ameliorates Age-Related Increase in DNA Damage, Senescence and Inflammation in Mouse Adipose Tissuey

por Ishaq, A., Schröder, J., Edwards, N., von Zglinicki, T., Saretzki, Gabriele
Publicado 2017

Palmitate induces DNA damage and senescence in human adipocytes in vitro that can be alleviated by oleic acid but not inorganic nitrate

por Ishaq, Abbas, Tchkonia, Tamara, Kirkland, James L., Siervo, Mario, Saretzki, Gabriele
Publicado 2022

Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis

por Singhapol, Chatchawan, Pal, Deepali, Czapiewski, Rafal, Porika, Mahendar, Nelson, Glyn, Saretzki, Gabriele C.
Publicado 2013

Telomerase and Telomeres in Endometrial Cancer

por Alnafakh, Rafah A. A., Adishesh, Meera, Button, Lucy, Saretzki, Gabriele, Hapangama, Dharani K.
Publicado 2019

The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome

por Chan, Danny, Martin-Ruiz, Carmen, Saretzki, Gabriele, Neely, Dermot, Qiu, Weiliang, Kunadian, Vijay
Publicado 2020

Endometriosis Is Associated with a Significant Increase in hTERC and Altered Telomere/Telomerase Associated Genes in the Eutopic Endometrium, an Ex-Vivo and In Silico Study

por Alnafakh, Rafah, Choi, Fiona, Bradfield, Alice, Adishesh, Meera, Saretzki, Gabriele, Hapangama, Dharani K.
Publicado 2020

Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson’s disease associated with enhanced autophagy

por Wan, Tengfei, Weir, Emma J., Johnson, Mary, Korolchuk, Viktor I., Saretzki, Gabriele C.
Publicado 2021

A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

por Lawless, Conor, Jurk, Diana, Gillespie, Colin S., Shanley, Daryl, Saretzki, Gabriele, von Zglinicki, Thomas, Passos, João F.
Publicado 2012

Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria

por Miwa, Satomi, Czapiewski, Rafal, Wan, Tengfei, Bell, Amy, Hill, Kirsten N., von Zglinicki, Thomas, Saretzki, Gabriele
Publicado 2016

Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

por Miwa, Satomi, Jow, Howsun, Baty, Karen, Johnson, Amy, Czapiewski, Rafal, Saretzki, Gabriele, Treumann, Achim, von Zglinicki, Thomas
Publicado 2014

Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation

por Chichagova, Valeria, Hallam, Dean, Collin, Joseph, Buskin, Adriana, Saretzki, Gabriele, Armstrong, Lyle, Yu-Wai-Man, Patrick, Lako, Majlinda, Steel, David H.
Publicado 2017

Adult-onset, short-term dietary restriction reduces cell senescence in mice

por Wang, Chunfang, Maddick, Mandy, Miwa, Satomi, Jurk, Diana, Czapiewski, Rafal, Saretzki, Gabriele, Langie, Sabine A.S., Godschalk, Roger W.L., Cameron, Kerry, von Zglinicki, Thomas
Publicado 2010