Identification and Characterization of Mortaparib(Plus)—A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-De...

por Sari, Anissa Nofita, Elwakeel, Ahmed, Dhanjal, Jaspreet Kaur, Kumar, Vipul, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Publicado 2021

Mutant p53(L194F) Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to Mortaparib(Plus), a Multimodal Small Molecule Inhibitor

por Elwakeel, Ahmed, Sari, Anissa Nofita, Dhanjal, Jaspreet Kaur, Meidinna, Hazna Noor, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Publicado 2021

Caffeic acid phenethyl ester (CAPE) confers wild type p53 function in p53(Y220C) mutant: bioinformatics and experimental evidence

por Radhakrishnan, Navaneethan, Dhanjal, Jaspreet Kaur, Sari, Anissa Nofita, Ishida, Yoshiyuki, Terao, Keiji, Kaul, Sunil C., Sundar, Durai, Wadhwa, Renu
Publicado 2021

Comparative computational and experimental analyses of some natural small molecules to restore transcriptional activation function of p53 in cancer cells harbouring wild type and p...

por Shefrin, Seyad, Sari, Anissa Nofita, Kumar, Vipul, Zhang, Huayue, Meidinna, Hazna Noor, Kaul, Sunil C., Wadhwa, Renu, Sundar, Durai
Publicado 2022

Identification of a new member of Mortaparib class of inhibitors that target mortalin and PARP1

por Meidinna, Hazna Noor, Shefrin, Seyad, Sari, Anissa Nofita, Zhang, Huayue, Dhanjal, Jaspreet Kaur, Kaul, Sunil C., Sundar, Durai, Wadhwa, Renu
Publicado 2022

Computational and in vitro experimental analyses of the anti-COVID-19 potential of Mortaparib and Mortaparib(Plus)

por Kumar, Vipul, Sari, Anissa Nofita, Meidinna, Hazna Noor, Dhanjal, Jaspreet Kaur, Subramani, Chandru, Basu, Brohmomoy, Kaul, Sunil C., Vrati, Sudhanshu, Sundar, Durai, Wadhwa, Renu
Publicado 2021

Wild type p53 function in p53(Y220C) mutant harboring cells by treatment with Ashwagandha derived anticancer withanolides: bioinformatics and experimental evidence

por Sundar, Durai, Yu, Yue, Katiyar, Shashank P., Putri, Jayarani F., Dhanjal, Jaspreet Kaur, Wang, Jia, Sari, Anissa Nofita, Kolettas, Evangelos, Kaul, Sunil C., Wadhwa, Renu
Publicado 2019

Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action

por Sari, Anissa Nofita, Bhargava, Priyanshu, Dhanjal, Jaspreet Kaur, Putri, Jayarani F., Radhakrishnan, Navaneethan, Shefrin, Seyad, Ishida, Yoshiyuki, Terao, Keiji, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Publicado 2020

A Low Dose Combination of Withaferin A and Caffeic Acid Phenethyl Ester Possesses Anti-Metastatic Potential In Vitro: Molecular Targets and Mechanisms

por Sari, Anissa Nofita, Dhanjal, Jaspreet Kaur, Elwakeel, Ahmed, Kumar, Vipul, Meidinna, Hazna Noor, Zhang, Huayue, Ishida, Yoshiyuki, Terao, Keiji, Sundar, Durai, Kaul, Sunil C., Wadhwa, Renu
Publicado 2022

Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells

por Wang, Jia, Bhargava, Priyanshu, Yu, Yue, Sari, Anissa Nofita, Zhang, Huayue, Ishii, Noriyuki, Yan, Kangmin, Zhang, Zhenya, Ishida, Yoshiyuki, Terao, Keiji, Kaul, Sunil C., Miyako, Eijiro, Wadhwa, Renu
Publicado 2020